Mutation Browse Page of dbEM

Browse by cancer mutants and normal variants sources

This page allow users to browse dbEM proteins by the source of cancer mutants i.e. CCLE and COSMIC and source of normal variants, 1000 genome. Following table contains the count of cancer mutants in CCLE and COSMIC and normal variants in 1000 Genome. Last column, Sum/1000 Genome depicts the ratio of mutation count in between cancer (CCLE and COSMIC) with normal variants (1000 Genome). Higher ratio indicates the more predisposition of mutations in cancer and vice versa. Please click here for help.

Protein	CCLE	COSMIC	Sum (CCLE+COSMIC)	1000 Genome	Sum/1000 Genome
ACTL6A	0	43	43	31	1.39
ACTL6B	0	46	46	14	3.29
ACTR5	0	44	44	28	1.57
ACTR8	0	37	37	24	1.54
ARID1A	172	821	993	87	11.41
ARID1B	0	170	170	88	1.93
ASH1L	0	277	277	84	3.30
CARM1	29	46	75	16	4.69
CDYL	0	71	71	58	1.22
CHD3	0	166	166	128	1.30
CHD4	0	134	134	45	2.98
CHRAC1	0	7	7	5	1.40
CREBBP	138	542	680	154	4.42
DNMT1	31	145	176	116	1.52
DNMT3A	8	1663	1671	82	20.38
DNMT3B	56	103	159	210	0.76
DOT1L	0	118	118	48	2.46
EHMT1	0	109	109	55	1.98
EHMT2	0	44	44	78	0.56
ELP3	0	36	36	75	0.48
EP300	148	359	507	99	5.12
EZH1	0	61	61	0	0.00
EZH2	46	608	654	102	6.41
FBXO10	0	75	75	30	2.50
GTF3C4	0	53	53	24	2.21
HAT1	0	39	39	13	3.00
HDAC1	22	43	65	11	5.91
HDAC10	0	26	26	84	0.31
HDAC11	0	39	39	23	1.70
HDAC2	60	49	109	6	18.17
HDAC3	29	39	68	7	9.71
HDAC4	47	126	173	62	2.79
HDAC5	0	67	67	0	0.00
HDAC6	35	111	146	22	6.64
HDAC7	0	60	60	0	0.00
HDAC8	12	18	30	0	0.00
HDAC9	0	200	200	198	1.01
HIF1AN	0	40	40	0	0.00
HINFP	0	48	48	0	0.00
HR	45	73	118	157	0.75
HSPBAP1	0	31	31	24	1.29
ING1	23	36	59	0	0.00
ING2	0	20	20	6	3.33
ING3	0	34	34	13	2.62
ING4	0	29	29	56	0.52
ING5	0	13	13	15	0.87
INO80	0	119	119	44	2.70
INO80B	0	22	22	9	2.44
INO80C	0	18	18	24	0.75
INO80D	0	66	66	30	2.20
INO80E	0	25	25	11	2.27
JARID2	39	135	174	120	1.45
JMJD1C	0	178	178	0	0.00
JMJD4	0	28	28	76	0.37
JMJD6	0	33	33	0	0.00
JMJD7	0	74	74	192	0.39
JMJD8	0	5	5	15	0.33
KAT2A	0	52	52	19	2.74
KAT2B	0	71	71	21	3.38
KAT5	0	36	36	0	0.00
KAT6A	0	0	0	201	0.00
KAT8	0	0	0	27	0.00
KDM1A	0	49	49	20	2.45
KDM1B	0	54	54	31	1.74
KDM2A	0	80	80	0	0.00
KDM2B	0	64	64	0	0.00
KDM3A	0	93	93	96	0.97
KDM3B	0	174	174	43	4.05
KDM4A	0	71	71	38	1.87
KDM4B	0	88	88	42	2.10
KDM4C	0	110	110	198	0.56
KDM4D	0	54	54	0	0.00
KDM5A	86	153	239	50	4.78
KDM5B	0	6	6	42	0.14
KDM5C	0	158	158	39	4.05
KDM5D	0	35	35	0	0.00
KDM6A	60	246	306	17	18.00
KDM6B	0	92	92	77	1.19
KDM7A	0	0	0	26	0.00
KDM8	0	0	0	45	0.00
KMT2C	0	0	0	175	0.00
KMT2E	0	0	0	102	0.00
MBD1	0	70	70	0	0.00
MBD2	0	23	23	0	0.00
MBD3	0	21	21	25	0.84
MBD4	0	53	53	131	0.40
MCRS1	0	40	40	0	0.00
MECP2	0	41	41	0	0.00
MGEA5	0	51	51	0	0.00
MINA	0	38	38	108	0.35
MTA1	0	59	59	0	0.00
MTA2	0	53	53	0	0.00
MTA3	0	39	39	53	0.74
NAT10	0	77	77	0	0.00
NCOA1	57	107	164	127	1.29
NCOA3	383	155	538	0	0.00
NFRKB	0	96	96	0	0.00
NSD1	76	212	288	146	1.97
PHF2	0	111	111	46	2.41
PHF8	0	88	88	57	1.54
PRDM2	0	144	144	266	0.54
PRDM9	0	333	333	33	10.09
PRMT1	0	30	30	0	0.00
PRMT2	0	34	34	0	0.00
PRMT3	0	50	50	75	0.67
PRMT5	0	53	53	46	1.15
PRMT6	0	32	32	4	8.00
PRMT7	0	49	49	0	0.00
PRMT8	0	80	80	32	2.50
PRMT9	0	0	0	43	0.00
RBBP4	0	36	36	27	1.33
RBBP7	0	58	58	9	6.44
RING1	0	38	38	8	4.75
RUVBL1	0	38	38	10	3.80
RUVBL2	0	2	2	0	0.00
SETD1A	0	139	139	69	2.01
SETD1B	0	31	31	0	0.00
SETD2	0	327	327	78	4.19
SETD3	0	56	56	0	0.00
SETD4	0	37	37	76	0.49
SETD5	0	106	106	41	2.59
SETD6	0	27	27	0	0.00
SETD7	0	35	35	12	2.92
SETD8	0	34	34	0	0.00
SETD9	0	0	0	30	0.00
SETDB1	45	91	136	82	1.66
SETDB2	0	47	47	48	0.98
SETMAR	0	30	30	75	0.40
SIRT1	25	37	62	0	0.00
SIRT2	0	27	27	0	0.00
SIRT3	0	28	28	46	0.61
SIRT4	0	27	27	0	0.00
SIRT5	0	24	24	64	0.38
SIRT6	0	16	16	40	0.40
SIRT7	0	35	35	0	0.00
SMARCA1	0	125	125	0	0.00
SMARCA4	97	312	409	429	0.95
SMARCA5	0	73	73	23	3.17
SMARCC1	0	82	82	35	2.34
SMARCC2	0	108	108	0	0.00
SMARCD1	0	36	36	0	0.00
SMARCD2	0	29	29	0	0.00
SMARCD3	0	52	52	40	1.30
SMYD1	0	92	92	35	2.63
SMYD2	0	40	40	12	3.33
SMYD3	0	41	41	43	0.95
SMYD4	0	50	50	45	1.11
SMYD5	0	23	23	16	1.44
SUV39H1	0	36	36	10	3.60
SUV39H2	0	40	40	0	0.00
SUV420H1	0	125	125	0	0.00
SUV420H2	0	20	20	0	0.00
TAF1	68	250	318	0	0.00
TET1	75	21	96	0	0.00
TET2	34	1608	1642	115	14.28
TFPT	20	17	37	0	0.00
UCHL5	0	40	40	31	1.29
UTY	0	22	22	0	0.00
WHSC1	80	137	217	220	0.99
WHSC1L1	47	43	90	49	1.84
YY1	0	18	18	0	0.00

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