dbEM

Protein: KAT6A

Mutation Data (+)

# Cell Line/Tumor sample Tissue of Origin cDNA change Protein change Source FATHMM Prediction PolyPhen2 Prediction

*NP: Not Predicted
Copy number variation and expression profile (+)

Expression and CNV data is not present for KAT6A!!
Gene Essentiality Data (+)

Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.

Gene essentiality data is not present in COLT database!!
Tertiary structure (+)

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Modelled Structure Structures available in PDB

1M36, 2LN0, 2OZU, 2RC4, 3V43, 4LJN, 4LK9, 4LKA, 4LLB,
Structure Domains (+)

1. PFAM Domains:

Domain ID Domain Name Start Site End Site E-value
PB019382 Pfam-B_19382 1 84 3.7e-50
PF00628 PHD 265 312 2.6e-10
PF01853 MOZ_SAS 562 746 2e-89
PB006470 Pfam-B_6470 1487 1600 1.5e-45

2. Superfamily Domains:

Domain ID Start Site End Site E-value
0053259 508 776 6.07e-112
0050474 251 322 1.20e-17
0051371 92 175 4.63e-07
0050474 195 263 2.66e-05

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1. Sequence alignment with 1000 genome variations:

Click on button to get Sequence alignment with Coverage, Consensus and Quality

2. Mutants are not present in CCLE!!

4. Mutants are not present in COSMIC!!

4. Sequence alignment with homologus proteins:

Click on button to get Sequence alignment with Coverage, Consensus and Quality

Modelled Structure	Structures available in PDB
	1M36, 2LN0, 2OZU, 2RC4, 3V43, 4LJN, 4LK9, 4LKA, 4LLB,