Papers published in PubMed in last 60 days
(Data retrieved on Thu Jun 11 17:00:24 IST 2015
)
- Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole.
- The phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERalpha expression and enhances hormonal therapy for breast cancer.
- Epigenetics in acute kidney injury.
- Histone Deacetylase Inhibition Rescues Maternal Deprivation-Induced GABAergic Metaplasticity through Restoration of AKAP Signaling.
- Epigenetics of obesity: beyond the genome sequence.
- You are what you eat: O-linked N-acetylglucosamine in disease, development and epigenetics.
- Beneficial effects of sodium butyrate in 6-OHDA induced neurotoxicity and behavioral abnormalities: Modulation of histone deacetylase activity.
- Optimization of histone deacetylase inhibitor activity in non-secosteroidal vitamin D-receptor agonist hybrids.
- Epigenetics. Exceptional epigenetics in the brain.
- Tissue-specific epigenetics in gene neighborhoods: Myogenic transcription factor genes.
- Epigenetics of Notch1 regulation in pulmonary microvascular rarefaction following extrauterine growth restriction.
- The Mitochondrial Side of Epigenetics.
- Histone deacetylase inhibitor entinostat inhibits tumor-initiating cells in triple negative breast cancer cells.
- [Antiapoptotic gene bcl-2 prevents cellular senescence program reactivation induced by histone deacetylase inhibitor sodium butyrate in E1A and cHa-ras transformed rat fibroblasts].
- Depletion of histone deacetylase 1 inhibits metastatic abilities of gastric cancer cells by regulating the miR-34a/CD44 pathway.
- Activation of latent human immunodeficiency virus by the histone deacetylase inhibitor panobinostat: a pilot study to assess effects on the central nervous system.
- Anticancer potential of the histone deacetylase inhibitor-like effects of flavones, a subclass of polyphenolic compounds: a review.
- Histone Deacetylase Inhibitors Resensitize EGFR/EGFRvIII-Overexpressing, Erlotinib-Resistant Glioblastoma Cells to Tyrosine Kinase Inhibition.
- Class I and II histone deacetylase expression in human chronic periodontitis gingival tissue.
- Epigenetics in autoimmune diseases: Pathogenesis and prospects for therapy.
- Epigenetics, Darwin and Lamarck.
- Histone Deacetylase (HDAC) Inhibitors: Current Evidence for Therapeutic Activities in Pancreatic Cancer.
- Contribution of epigenetics in diabetic retinopathy. with diabetes becoming at a risk of developing retinopathy, diabetic retinopathy
- Histone deacetylase HDAC1 downregulates transcription of the serotonin transporter (5-HTT) gene in tumor cells.
- [Histone deacetylase inhibitors cause the TP53-dependent induction of p21/Waf1 in tumor cells carrying mutations in TP53].
- A miniaturized readout strategy for endogenous histone deacetylase activity. characterize due to their poor accessibility. We have developed a miniaturized
- DECIDER: prospective randomized multicenter phase II trial of low-dose decitabine (DAC) administered alone or in combination with the histone deacetylase inhibitor valproic acid (VPA) and all-trans retinoic acid (ATRA) in patients >60 years with
- Reproductive endocrinology: Epigenetics in pregnancy.
- Discovery of a new class of histone deacetylase inhibitors with a novel zinc binding group.
- Antitumour activity of AMG 900 alone or in combination with histone deacetylase inhibitor SaHa on medulloblastoma cell lines.
- Histone deacetylase inhibitors: a review on class-I specific inhibition.
- Recent developments in epigenetics of acute and chronic kidney diseases.
- Novel Bioactive Hybrid Compound Dual Targeting Estrogen Receptor and Histone Deacetylase for the Treatment of Breast Cancer.
- EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells.
- A lazy learning-based QSAR classification study for screening potential histone deacetylase 8 (HDAC8) inhibitors.
- Introduction to progress and promise of epigenetics for diagnosis and therapy in cancer.
- Epigenetics of Posttraumatic Stress Disorder: Current Evidence, Challenges, and Future Directions.
- The role of epigenetics in the endothelial cell shear stress response and atherosclerosis.
- Rational combination treatment with histone deacetylase inhibitors and immunomodulatory drugs in multiple myeloma.
- The diagnostic and clinical impact of genetics and epigenetics in acute myeloid leukemia.
- Inhibiting histone deacetylase 6 partly protects cultured rat cortical neurons from oxygenglucose deprivationinduced necroptosis.
- Emerging Interplay of Genetics and Epigenetics in Gliomas: A New Hope for Targeted Therapy.
- Structural diversity of the epigenetics pocketome.
- Histone deacetylase 3 inhibits new tumor suppressor gene DTWD1 in gastric cancer.
- Treatment of chronic kidney diseases with histone deacetylase inhibitors.
- GLAST But Not Least-Distribution, Function, Genetics and Epigenetics of L-Glutamate Transport in Brain-Focus on GLAST/EAAT1.
- Discovery of bicyclic pyrazoles as class III histone deacetylase SIRT1 and SIRT2 inhibitors.
- Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors.
- Stroke Induces Nuclear Shuttling of Histone Deacetylase 4.
- Building up and knocking down: An emerging role for epigenetics and proteasomal degradation in systems consolidation.
- Epigenetics and pharmacology.
- Epigenetics Meets Immune Checkpoints.
- The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells.
- Quantification of histone deacetylase isoforms in human frontal cortex, human retina, and mouse brain.
- Epigenetics and miRNA as predictive markers and targets for lung cancer chemotherapy.
- The role of AP-1 and epigenetics in ALCL.
- Epigenetics and Osteoarthritis.
- Neuroscience, epigenetics and the intergenerational transmission of social life: exploring expectations and engagements.
- A novel class I histone deacetylase inhibitor, I-7ab, induces apoptosis and arrests cell cycle progression in human colorectal cancer cells.
- The histone deacetylase sirtuin 2 is a new player in the regulation of platelet function.
- [Epigenetics and drug addiction: a focus on MeCP2 and on histone acetylation].
- Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation.
- Correction: Histone Deacetylase Inhibition Enhances Tissue Plasminogen Activator Release Capacity in Atherosclerotic Man.
- Epigenetics. Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing.
- Discovery, bioactivity and docking simulation of Vorinostat analogues containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors and antitumor agents.
- A role for epigenetics in the formation of chromosome translocations in acute leukemia.
- The role of epigenetics in personalized medicine: challenges and opportunities.
- Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells.
- Heart failure: advanced development in genetics and epigenetics.
- HDACiDB: a database for histone deacetylase inhibitors.
- Analysis of class I and II histone deacetylase gene expression in human leukemia.
- Role of chromatin structure modulation by the histone deacetylase inhibitor trichostatin A on the radio-sensitivity of ataxia telangiectasia.
- Barcelona conference on epigenetics and cancer: 50 years of histone acetylation.
- The Histone Deacetylase Inhibitor Valproic Acid Sensitizes Gemcitabine-Induced Cytotoxicity in Gemcitabine-Resistant Pancreatic Cancer Cells Possibly Through Inhibition of the DNA Repair Protein Gamma-H2AX.
- [Cigarette smoke extract induces senescence of murine skeletal muscle cells by oxidative stress-induced down-regulation of histone deacetylase 2].
- In reply-Epigenetics and Childhood Obesity.
- Epigenetics and childhood obesity.
- Epigenetics in the wild.
- Epigenetics in lung cancer diagnosis and therapy. initiation and progression of lung cancer is the result of the interaction
- Protective Effects of Valproic Acid, a Histone Deacetylase Inhibitor, against Hyperoxic Lung Injury in a Neonatal Rat Model.
- Murine hematopoietic stem cell dormancy controlled by induction of a novel short form of PSF1 by histone deacetylase inhibitors.
- Editorial: Genetics and epigenetics of fetal alcohol spectrum disorders.
- (P039) outcomes of patients with glioblastoma receiving concurrent radiation treatment and antiepileptic agents with histone deacetylase inhibitor activity.
- [Histone deacetylase 6: structure, functions and development of selective inhibitors].
- Regulation of flowering time by the histone deacetylase HDA5 in Arabidopsis.
- The Mechanism and Function of Epigenetics in Uterine Leiomyoma Development.
- Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways.
- Environmental Epigenetics and a Unified Theory of the Molecular Aspects of Evolution: A Neo-Lamarckian Concept that Facilitates Neo-Darwinian Evolution.
- Epigenetics of aging.
- The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.
- Electrocardiographic effects of class 1 selective histone deacetylase inhibitor romidepsin.
- Manipulation of B-cell responses with histone deacetylase inhibitors.
- The genetics of loneliness: linking evolutionary theory to genome-wide genetics, epigenetics, and social science.
- Design, synthesis, and antitumor evaluation of novel histone deacetylase inhibitors equipped with a phenylsulfonylfuroxan module as a nitric oxide donor.
- Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells.
- Diverse involvement of EZH2 in cancer epigenetics.
- Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids.
- Histone Deacetylase Inhibitor Romidepsin Inhibits de novo HIV-1 Infections.
- Emerging approaches for histone deacetylase inhibitor drug discovery.
- Hydroxamate-Based Histone Deacetylase Inhibitors Can Protect Neurons from Oxidative Stress via a Histone Deacetylase-Independent Catalase-Like Mechanism.
- Epigenetics, society, and bio-objects.
- Mitochondrial epigenetics: an overlooked layer of regulation?
- Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells.
- Inhibition of breast cancer progression by a novel histone deacetylase inhibitor, LW479, through down-regulating EGFR expression.
- A phosphorescent rhenium(i) histone deacetylase inhibitor: mitochondrial targeting and paraptosis induction.
- Hybrids from Farnesylthiosalicylic Acid and Hydroxamic Acid as Dual Ras-Related Signaling and Histone Deacetylase (HDAC) Inhibitors: Design, Synthesis and Biological Evaluation.
- Epigenetics in Cystic Fibrosis: Epigenetic Targeting of a Genetic Disease. digestive system. A mutation in the CF transmembrane conductance regulator (CFTR)
- Marine Actinomycetes as potential source for histone deacetylase inhibitors and epigenetic modulation.
- Restoring histone deacetylase activity by waste product release. A view from molecular mechanics simulations with mammalian HDAC8.
- Correction: autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors.
- The epigenetics of multiple sclerosis and other related disorders.
- Epigenetics: An Emerging Framework for Advanced Practice Psychiatric Nursing.
- Histone deacetylase inhibitors: potent anti-leukemic agents.
- Deletion of Histone Deacetylase 7 in Osteoclasts Decreases Bone Mass in Mice by Interactions with MITF.
- Epigenetics: Characterizing enhancers with dCas9.
- Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors.
- Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement.
- [The histone deacetylase sirtuins modulate cell autophagy in cardiovascular diseases].
- The histone deacetylase inhibitor panobinostat lowers biomarkers of cardiovascular risk and inflammation in HIV patients.
- Is There a Link Between Expression Levels of Histone Deacetylase/Acetyltransferase in Mouse Sperm and Subsequent Blastocyst Development?
- Chemical tools for probing histone deacetylase (HDAC) activity.
- The relationship of CD133, histone deacetylase 1 and thrombospondin-1 in gastric cancer.