A Database of Epigenetic Modifiers
We are thankful to the authors and developers of following tools and databases used in dbEM.
| Name of Resource/Database/Software | Publication |
|---|---|
| COSMIC:Catalogue of Somatic Mutation in Cancer is the vast collection of mutations in large number of sample from where we took mutation reported in epigenetics proteins | PMID: 22460902 |
| CCLE: From CCLE, we took mutational, gene expression and copynumber variation data of epigeneticsi proteins. | PMID: 22460905 |
| BLAST: BLAST algorithm was used to search user defined in set of epigenetics proteins. | PMID:2231712 |
| HHblits: HHblit suite was used to search the best template(s) for the structure prediction. | PMID:22198341 |
| Jalview: Jalview was used for visualization of sequence alignnment and dendrogram of mutants. | PMID:19151095 |
| Jmol: JmolApplet was implemented for the visualization of predicted tertiary structure. | Jmol |
| MODELLER: MODELLER software has been used for the prediction of tertiary structure of epigenetics proteins. | PMID:18428767 |
| COLT-cancer Database: From this database, we took the gene essentiality profile of epigenetics genes. | PMC3245009 |