dbEM

Protein: KDM7A

Mutation Data (+)

# Cell Line/Tumor sample Tissue of Origin cDNA change Protein change Source FATHMM Prediction PolyPhen2 Prediction

*NP: Not Predicted
Copy number variation and expression profile (+)

Expression and CNV data is not present for KDM7A!!
Gene Essentiality Data (+)

Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.

Gene essentiality data is not present in COLT database!!
Tertiary structure (+)

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Modelled Structure Structures available in PDB

3KV5, 3KV6, 3KV9, 3KVA, 3KVB, 3U78,
Structure Domains (+)

1. PFAM Domains:

Domain ID Domain Name Start Site End Site E-value
PB003779 Pfam-B_3779 37 66 7.8e-08
PF00628 PHD 39 86 1e-08
PF02373 JmjC 269 369 3.2e-10
PB018122 Pfam-B_18122 381 539 9e-104
PB013686 Pfam-B_13686 541 639 2.2e-45

2. Superfamily Domains:

Domain ID Start Site End Site E-value
0047105 140 408 5.49e-59
0050470 32 101 2.88e-19

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1. Sequence alignment with 1000 genome variations:

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2. Mutants are not present in CCLE!!

4. Mutants are not present in COSMIC!!

4. Sequence alignment with homologus proteins:

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Modelled Structure	Structures available in PDB
	3KV5, 3KV6, 3KV9, 3KVA, 3KVB, 3U78,