dbEM
A Database of Epigenetic Modifiers
Cite: Nanda JS, Kumar R, Raghava GP. (2016) dbEM: A database of epigenetic modifiers curated from cancerous and normal genomes. Sci Rep. 6:19340.
Protein: DNMT3A |
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Mutation Data (+)
# Cell Line/Tumor sample Tissue of Origin cDNA change Protein change Source FATHMM Prediction PolyPhen2 Prediction 1 GP2D LARGE INTESTINE c.248A>G p.D83G CCLE NP Benign 2 JHUEM2 ENDOMETRIUM c.891C>A p.S297S CCLE NP NP 3 KP4 PANCREAS c.445C>T p.R149W CCLE NP NP 4 NCIH82 LUNG c.846G>A p.L282L CCLE NP NP 5 NIHOVCAR3 OVARY c.341G>A p.R114K CCLE NP NP 6 ONCODG1 OVARY c.341G>A p.R114K CCLE NP NP 7 REH HAEMATOPOIETIC AND LYMPHOID TISSUE c.328G>A p.G110R CCLE NP NP 8 SNU886 LIVER c.410C>G p.T137R CCLE NP NP 9 001 KIDNEY c.168G>T p.K56N COSMIC PASSENGER/OTHER Possibly Damaging 10 100831 LUNG c.113G>A p.R38H COSMIC PASSENGER/OTHER Probably Damaging 11 101286 LUNG c.2687C>T p.P896L COSMIC CANCER Probably Damaging 12 112140 LUNG c.652G>C p.A218P COSMIC PASSENGER/OTHER Benign 13 1174 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 14 1436364 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 15 1462520 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 16 1462528 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 17 1462530 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 18 1462534 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1768_1768delG p.G590fs*61 COSMIC NP NP 19 1462534 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1_2739 p.0 COSMIC NP NP 20 1462538 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 21 1462546 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 22 1462547 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 23 1462565 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 24 1462568 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 25 1462583 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 26 1462588 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 27 1462591 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 28 1462601 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 29 1462608 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 30 1462615 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 31 1462624 HAEMATOPOIETIC AND LYMPHOID TISSUE c.943_943delA p.M315fs*1 COSMIC NP NP 32 1462649 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 33 1462650 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 34 1462653 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 35 1462655 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1846_1846delG p.E616fs*35 COSMIC NP NP 36 1462657 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 37 1462658 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 38 1462666 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 39 1462670 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 40 1462671 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 41 1462682 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 42 1462688 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2168_2168delT p.L723fs*56 COSMIC NP NP 43 1462689 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 44 1462697 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 45 1462698 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 46 1465804 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 47 1465807 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 48 1465810 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 49 1465830 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2481_2481delC p.F827fs*4 COSMIC NP NP 50 1465835 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 51 1465839 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 52 1465844 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 53 1465845 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 54 1465846 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2196_2197insT p.E733fs*1 COSMIC NP NP 55 1465866 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 56 1500311 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 57 1500312 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 58 1500313 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 59 1500314 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 60 1500315 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 61 1500316 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 62 1500317 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 63 1500318 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 64 1500319 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1432C>T p.R478W COSMIC PASSENGER/OTHER Probably Damaging 65 1500319 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 66 1500320 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 67 1500321 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 68 1500322 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 69 1500323 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 70 1500324 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 71 1500325 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 72 1500326 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 73 1500327 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 74 1500328 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 75 1500329 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 76 1500330 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 77 1500331 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 78 1500332 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1627G>T p.G543C COSMIC PASSENGER/OTHER Probably Damaging 79 1500420 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 80 1500421 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 81 1500422 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 82 1500423 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 83 1500424 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2711C>T p.P904L COSMIC CANCER Probably Damaging 84 1500425 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2210T>G p.L737R COSMIC PASSENGER/OTHER Probably Damaging 85 1500425 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2711C>T p.P904L COSMIC CANCER Probably Damaging 86 1500426 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2312G>T p.R771L COSMIC PASSENGER/OTHER Probably Damaging 87 1500427 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2309C>G p.S770W COSMIC PASSENGER/OTHER Probably Damaging 88 1500428 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 89 1500429 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1903C>T p.R635W COSMIC PASSENGER/OTHER Probably Damaging 90 1500430 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1264_1265ins22 p.L422fs*6 COSMIC NP NP 91 1500431 HAEMATOPOIETIC AND LYMPHOID TISSUE c.709C>T p.Q237* COSMIC NP NP 92 1521819 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 93 1521820 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2621A>G p.Y874C COSMIC CANCER Probably Damaging 94 1521821 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 95 1521822 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 96 1521823 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 97 1521824 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 98 1521825 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 99 1537289 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 100 1537290 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 101 1549705 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2446C>T p.Q816* COSMIC NP NP 102 1549706 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 103 1549721 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 104 1549722 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2096G>A p.G699D COSMIC PASSENGER/OTHER Probably Damaging 105 1549723 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 106 1549724 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 107 1549732 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2191_2193delTTC p.F731del COSMIC NP NP 108 1557461 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 109 1560883 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2638A>G p.M880V COSMIC CANCER Possibly Damaging 110 1560884 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2638A>G p.M880V COSMIC CANCER Possibly Damaging 111 1560885 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 112 1560886 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 113 1560887 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 114 1560888 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 115 1560889 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 116 1588668 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1906G>A p.V636M COSMIC PASSENGER/OTHER Probably Damaging 117 1588672 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2204A>G p.Y735C COSMIC PASSENGER/OTHER Probably Damaging 118 1588673 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1743G>T p.W581C COSMIC CANCER Probably Damaging 119 1588674 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2261T>G p.L754R COSMIC PASSENGER/OTHER Probably Damaging 120 1588675 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1055G>A p.S352N COSMIC PASSENGER/OTHER Benign 121 1588676 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2546C>G p.P849R COSMIC CANCER Probably Damaging 122 1588677 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2254T>C p.F752L COSMIC PASSENGER/OTHER Probably Damaging 123 1588678 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2254T>C p.F752L COSMIC PASSENGER/OTHER Probably Damaging 124 1588685 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2192T>G p.F731C COSMIC PASSENGER/OTHER Probably Damaging 125 1588685 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2666T>C p.L889P COSMIC CANCER Probably Damaging 126 1588686 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2257T>G p.W753G COSMIC PASSENGER/OTHER Probably Damaging 127 1588687 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2385G>C p.W795C COSMIC CANCER Probably Damaging 128 1588688 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2385G>C p.W795C COSMIC CANCER Probably Damaging 129 1588689 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1964T>A p.I655N COSMIC PASSENGER/OTHER Probably Damaging 130 1588691 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2729C>T p.A910V COSMIC CANCER Probably Damaging 131 1593995 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 132 15D HAEMATOPOIETIC AND LYMPHOID TISSUE c.2053G>A p.G685R COSMIC PASSENGER/OTHER Probably Damaging 133 1604488 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 134 1604489 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 135 1604490 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 136 1604491 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 137 1604492 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 138 1604493 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 139 1604494 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 140 1604495 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 141 1604496 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 142 1604497 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 143 1604498 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 144 1604499 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 145 1604500 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 146 1604501 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 147 1604502 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 148 1604503 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 149 1606638 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 150 1606639 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 151 1606640 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 152 1606641 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 153 1606642 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 154 1606643 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 155 1606644 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 156 1606645 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 157 1606646 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 158 1606647 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2120_2120delG p.G707fs*72 COSMIC NP NP 159 1606648 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 160 1606649 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 161 1606650 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 162 1606651 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1865_1866insGT p.Y623fs*29 COSMIC NP NP 163 1606652 HAEMATOPOIETIC AND LYMPHOID TISSUE c.890G>A p.W297* COSMIC NP NP 164 1606653 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 165 1606654 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 166 1606655 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 167 1606656 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2606_2606delG p.G869fs*12 COSMIC NP NP 168 1606657 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2389A>T p.N797Y COSMIC CANCER Probably Damaging 169 1606658 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 170 1606659 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 171 1606660 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1477_1477delA p.I493fs*158 COSMIC NP NP 172 1606661 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 173 1606662 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 174 1606663 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2246_2249delGCCC p.R749fs*29 COSMIC NP NP 175 1606664 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 176 1606665 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 177 1606666 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2113A>T p.I705F COSMIC PASSENGER/OTHER Probably Damaging 178 1606667 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 179 1606668 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 180 1606669 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 181 1606670 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 182 1606671 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 183 1606672 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 184 1606673 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 185 1606674 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 186 1606675 HAEMATOPOIETIC AND LYMPHOID TISSUE c.958C>T p.R320* COSMIC NP NP 187 1606676 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1816C>T p.Q606* COSMIC NP NP 188 1606677 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2255_2257delTCT p.F752del COSMIC NP NP 189 1606678 HAEMATOPOIETIC AND LYMPHOID TISSUE c.958C>T p.R320* COSMIC NP NP 190 1606679 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 191 1606680 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1572T>A p.C524* COSMIC NP NP 192 1606680 HAEMATOPOIETIC AND LYMPHOID TISSUE c.315C>A p.S105R COSMIC PASSENGER/OTHER Probably Damaging 193 1606681 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 194 1606682 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 195 1606683 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 196 1606684 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 197 1606685 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1001_1001delG p.G334fs*11 COSMIC NP NP 198 1606686 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 199 1606687 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 200 1606688 HAEMATOPOIETIC AND LYMPHOID TISSUE c.767_770delCCAC p.P256fs*59 COSMIC NP NP 201 1606689 HAEMATOPOIETIC AND LYMPHOID TISSUE c.327_328insG p.Q110fs*14 COSMIC NP NP 202 1606690 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 203 1606691 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 204 1606692 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 205 1606693 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 206 1606694 HAEMATOPOIETIC AND LYMPHOID TISSUE c.866_866delG p.G289fs*27 COSMIC NP NP 207 1606695 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 208 1606696 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 209 1606697 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2510C>G p.S837* COSMIC NP NP 210 1606698 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 211 1606699 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2312G>A p.R771Q COSMIC PASSENGER/OTHER Probably Damaging 212 1606700 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 213 1606701 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2182G>C p.G728R COSMIC PASSENGER/OTHER Probably Damaging 214 1606701 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2191T>C p.F731L COSMIC PASSENGER/OTHER Probably Damaging 215 1606702 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2207G>A p.R736H COSMIC PASSENGER/OTHER Probably Damaging 216 1606702 HAEMATOPOIETIC AND LYMPHOID TISSUE c.941G>A p.W314* COSMIC NP NP 217 1606703 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2207G>A p.R736H COSMIC PASSENGER/OTHER Probably Damaging 218 1606704 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1792C>T p.R598* COSMIC NP NP 219 1606705 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2032C>T p.Q678* COSMIC NP NP 220 1606705 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2210T>A p.L737H COSMIC PASSENGER/OTHER Probably Damaging 221 1606706 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1903C>T p.R635W COSMIC PASSENGER/OTHER Probably Damaging 222 1606707 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2207G>A p.R736H COSMIC PASSENGER/OTHER Probably Damaging 223 1636693 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1869C>A p.Y623* COSMIC NP NP 224 1636694 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 225 1636695 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 226 1636696 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2191_2193delTTC p.F731del COSMIC NP NP 227 1636697 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2191_2193delTTC p.F731del COSMIC NP NP 228 1636698 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2191_2193delTTC p.F731del COSMIC NP NP 229 1636699 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2191_2193delTTC p.F731del COSMIC NP NP 230 1636700 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2191_2193delTTC p.F731del COSMIC NP NP 231 1636701 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2191_2193delTTC p.F731del COSMIC NP NP 232 1636702 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1604_1605ins21 p.S535>YDDDGYQS COSMIC NP NP 233 1636703 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1604_1605ins21 p.S535>YDDDGYQS COSMIC NP NP 234 1636704 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2058_2064delCGTCCGC p.D686fs*17 COSMIC NP NP 235 1636705 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2058_2064delCGTCCGC p.D686fs*17 COSMIC NP NP 236 1636706 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2667_2668delGG p.G890fs*24 COSMIC NP NP 237 1636707 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 238 1636708 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1118T>C p.L373P COSMIC PASSENGER/OTHER Probably Damaging 239 1636709 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1118T>C p.L373P COSMIC PASSENGER/OTHER Probably Damaging 240 1636710 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 241 1636711 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 242 1636713 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2284_2285insCCATGG p.G762>AMG COSMIC NP NP 243 1636714 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2284_2285insCCATGG p.G762>AMG COSMIC NP NP 244 1636715 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2284_2285insCCATGG p.G762>AMG COSMIC NP NP 245 1636716 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2284_2285insCCATGG p.G762>AMG COSMIC NP NP 246 1639301 HAEMATOPOIETIC AND LYMPHOID TISSUE c.(1516_1518)delC p.(H506_L508)fs*(143-145) COSMIC NP NP 247 1639304 HAEMATOPOIETIC AND LYMPHOID TISSUE c.(1740_1743)insC p.W581fs*31 COSMIC NP NP 248 1639307 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1852_1852delG p.D618fs*33 COSMIC NP NP 249 1639315 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2333_2333delT p.V778fs*2 COSMIC NP NP 250 1639991 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 251 1639992 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 252 1639993 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 253 1639994 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 254 1639995 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 255 1639996 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 256 1639997 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1729A>T p.K577* COSMIC NP NP 257 1673522 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 258 1673523 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 259 1673524 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 260 1673525 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 261 1673526 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 262 1673527 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 263 1673528 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 264 1673529 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 265 1673530 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 266 1673531 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 267 1673532 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 268 1673533 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 269 1673534 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 270 1673535 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 271 1673536 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 272 1673537 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 273 1673538 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 274 1673539 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 275 1673540 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 276 1673541 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 277 1673542 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 278 1673543 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1903C>T p.R635W COSMIC PASSENGER/OTHER Probably Damaging 279 1673543 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 280 1673544 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2506A>T p.R836W COSMIC CANCER Probably Damaging 281 1673544 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 282 1673545 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 283 1673546 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 284 1673547 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 285 1673548 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 286 1673549 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 287 1673550 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 288 1673551 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 289 1673552 HAEMATOPOIETIC AND LYMPHOID TISSUE c.859_859delG p.G287fs*29 COSMIC NP NP 290 1673553 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2246_2246delG p.R749fs*30 COSMIC NP NP 291 1673554 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2485A>T p.K829* COSMIC NP NP 292 1673555 HAEMATOPOIETIC AND LYMPHOID TISSUE c.920C>G p.P307R COSMIC CANCER Probably Damaging 293 1673556 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2345C>A p.A782D COSMIC CANCER Probably Damaging 294 1673557 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2678G>C p.W893S COSMIC CANCER Probably Damaging 295 1696473 HAEMATOPOIETIC AND LYMPHOID TISSUE c.917G>A p.W306* COSMIC NP NP 296 1696474 HAEMATOPOIETIC AND LYMPHOID TISSUE c.990G>A p.W330* COSMIC NP NP 297 1696475 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1220T>G p.I407S COSMIC PASSENGER/OTHER Probably Damaging 298 1696476 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1220T>C p.I407T COSMIC PASSENGER/OTHER Probably Damaging 299 1696477 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1748G>A p.C583Y COSMIC CANCER Probably Damaging 300 1696479 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2128T>A p.C710S COSMIC CANCER Probably Damaging 301 1696480 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2151C>T p.N717N COSMIC NP NP 302 1696481 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 303 1696482 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 304 1696483 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 305 1696484 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 306 1696485 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 307 1696486 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 308 1696487 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 309 1696488 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 310 1696489 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 311 1696490 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 312 1696491 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 313 1696492 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2677T>A p.W893R COSMIC CANCER Probably Damaging 314 1697573 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2711C>T p.P904L COSMIC CANCER Probably Damaging 315 1697584 HAEMATOPOIETIC AND LYMPHOID TISSUE c.993_994insC p.G332fs*11 COSMIC NP NP 316 1697590 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 317 1722998 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 318 1722999 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 319 1723000 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 320 1723001 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 321 1735171 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1628G>C p.G543A COSMIC PASSENGER/OTHER Probably Damaging 322 1735172 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 323 1735178 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 324 1735182 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2396C>G p.P799R COSMIC CANCER Probably Damaging 325 1735184 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 326 1735185 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1792C>T p.R598* COSMIC NP NP 327 1735186 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1648G>A p.G550R COSMIC PASSENGER/OTHER Probably Damaging 328 1735188 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 329 1735189 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 330 1735191 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 331 1735195 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 332 1735197 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1979A>G p.Y660C COSMIC PASSENGER/OTHER Probably Damaging 333 1735197 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2409_2478del70 p.R803fs*5 COSMIC NP NP 334 1735199 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 335 1735203 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 336 1735205 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 337 1735207 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 338 1735208 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1740_1741insC p.W581fs*31 COSMIC NP NP 339 1735210 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 340 1735212 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2323_2408del86 p.S775fs*8 COSMIC NP NP 341 1735213 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 342 1735214 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1516_1516delC p.H506fs*145 COSMIC NP NP 343 1735215 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 344 1735225 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 345 1735226 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1928_1929insT p.A644fs*24 COSMIC NP NP 346 1735226 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2669G>A p.G890D COSMIC CANCER Probably Damaging 347 1735228 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 348 1735229 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 349 1735230 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1507A>G p.T503A COSMIC PASSENGER/OTHER Benign 350 1735237 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 351 1735241 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 352 1735242 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 353 1735245 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1990G>A p.E664K COSMIC PASSENGER/OTHER Probably Damaging 354 1735245 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2409_2478del70 p.R803fs*5 COSMIC NP NP 355 1735247 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 356 1747 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 357 1751604 HAEMATOPOIETIC AND LYMPHOID TISSUE c.89A>C p.E30A COSMIC PASSENGER/OTHER Possibly Damaging 358 1751605 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 359 1751614 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2312G>A p.R771Q COSMIC PASSENGER/OTHER Probably Damaging 360 1762573 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2026C>T p.R676W COSMIC PASSENGER/OTHER Probably Damaging 361 1766 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 362 1768270 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 363 1768273 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 364 1769079 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 365 1769080 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 366 1769096 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1741T>C p.W581R COSMIC CANCER Probably Damaging 367 1769097 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 368 1769098 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 369 1769100 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2204A>G p.Y735C COSMIC PASSENGER/OTHER Probably Damaging 370 1796122 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 371 1796123 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 372 1796124 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 373 1796125 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 374 1796126 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 375 1796127 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 376 1796128 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 377 1796129 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 378 1796130 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 379 1796131 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2704_2706delTTC p.F902del COSMIC NP NP 380 1796132 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 381 1796133 LUNG c.2704_2706delTTC p.F902del COSMIC NP NP 382 1796134 LUNG c.2731T>C p.C911R COSMIC PASSENGER/OTHER Probably Damaging 383 1796135 LUNG c.2370G>T p.R790S COSMIC CANCER Probably Damaging 384 1856822 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 385 1856823 HAEMATOPOIETIC AND LYMPHOID TISSUE c.914G>A p.W305* COSMIC NP NP 386 1856824 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 387 1856825 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2096G>A p.G699D COSMIC PASSENGER/OTHER Probably Damaging 388 1856826 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2502_2531del30 p.T835_K844del COSMIC NP NP 389 1856827 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2501C>T p.T834I COSMIC CANCER Probably Damaging 390 1856828 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2501C>T p.T834I COSMIC CANCER Probably Damaging 391 1856829 HAEMATOPOIETIC AND LYMPHOID TISSUE c.55C>T p.R19W COSMIC PASSENGER/OTHER Probably Damaging 392 1856830 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2202C>A p.F734L COSMIC PASSENGER/OTHER Probably Damaging 393 1856831 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 394 1856832 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 395 1856833 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1906G>A p.V636M COSMIC PASSENGER/OTHER Probably Damaging 396 1856833 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2191T>C p.F731L COSMIC PASSENGER/OTHER Probably Damaging 397 1856834 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 398 1856835 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1792C>T p.R598* COSMIC NP NP 399 1856835 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2375G>A p.R792H COSMIC CANCER Probably Damaging 400 1857010 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2242G>A p.D748N COSMIC PASSENGER/OTHER Benign 401 1857011 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 402 1857012 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 403 1857013 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 404 1857014 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2688A>G p.P896P COSMIC NP NP 405 1950485 HAEMATOPOIETIC AND LYMPHOID TISSUE c.317C>G p.P106R COSMIC PASSENGER/OTHER Benign 406 1950486 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1339_1339delG p.A447fs*204 COSMIC NP NP 407 1950487 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1429G>T p.E477* COSMIC NP NP 408 1950488 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1341_1342insC p.Y448fs*25 COSMIC NP NP 409 1950489 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1304_1305insT p.Y436fs*9 COSMIC NP NP 410 1950490 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1453_1453delC p.Q485fs*166 COSMIC NP NP 411 1950491 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1430_1433delAGCG p.E477fs*173 COSMIC NP NP 412 1950493 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1502A>G p.N501S COSMIC PASSENGER/OTHER Benign 413 1950494 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1489T>G p.C497G COSMIC PASSENGER/OTHER Probably Damaging 414 1950495 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1526_1535del10 p.F509fs*1 COSMIC NP NP 415 1950496 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1534G>A p.G512R COSMIC PASSENGER/OTHER Probably Damaging 416 1950497 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1506_1506delT p.T503fs*148 COSMIC NP NP 417 1950498 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1481G>A p.C494Y COSMIC PASSENGER/OTHER Probably Damaging 418 1950499 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1490G>A p.C497Y COSMIC PASSENGER/OTHER Probably Damaging 419 1950500 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1502A>G p.N501S COSMIC PASSENGER/OTHER Benign 420 1950501 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1512_1512delG p.E505fs*146 COSMIC NP NP 421 1950502 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1531G>A p.G511R COSMIC PASSENGER/OTHER Probably Damaging 422 1950503 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1502A>C p.N501T COSMIC PASSENGER/OTHER Possibly Damaging 423 1950504 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1628G>C p.G543A COSMIC PASSENGER/OTHER Probably Damaging 424 1950505 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1640T>C p.L547P COSMIC PASSENGER/OTHER Possibly Damaging 425 1950506 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1628_1628delG p.G543fs*108 COSMIC NP NP 426 1950507 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1665C>A p.C555* COSMIC NP NP 427 1950508 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1627G>T p.G543C COSMIC PASSENGER/OTHER Probably Damaging 428 1950509 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1581G>C p.Q527H COSMIC PASSENGER/OTHER Benign 429 1950510 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1640T>A p.L547H COSMIC PASSENGER/OTHER Probably Damaging 430 1950511 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1627G>T p.G543C COSMIC PASSENGER/OTHER Probably Damaging 431 1950512 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1627G>T p.G543C COSMIC PASSENGER/OTHER Probably Damaging 432 1950513 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1627G>T p.G543C COSMIC PASSENGER/OTHER Probably Damaging 433 1950514 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1648G>A p.G550R COSMIC PASSENGER/OTHER Probably Damaging 434 1950515 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1628G>T p.G543V COSMIC PASSENGER/OTHER Probably Damaging 435 1950516 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1609T>G p.C537G COSMIC PASSENGER/OTHER Probably Damaging 436 1950517 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1609T>G p.C537G COSMIC PASSENGER/OTHER Probably Damaging 437 1950518 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1591G>A p.D531N COSMIC PASSENGER/OTHER Probably Damaging 438 1950519 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1583_1585delACG p.D529del COSMIC NP NP 439 1950520 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1743G>A p.W581* COSMIC NP NP 440 1950521 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1648G>A p.G550R COSMIC PASSENGER/OTHER Probably Damaging 441 1950522 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1698_1700delGGT p.V567del COSMIC NP NP 442 1950523 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1779_1779delG p.L594fs*57 COSMIC NP NP 443 1950524 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1741T>G p.W581G COSMIC CANCER Probably Damaging 444 1950525 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1840G>A p.D614N COSMIC PASSENGER/OTHER Benign 445 1950526 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1792C>T p.R598* COSMIC NP NP 446 1950527 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1669T>C p.C557R COSMIC PASSENGER/OTHER Possibly Damaging 447 1950528 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1705_1716del12 p.P569_A572del COSMIC NP NP 448 1950529 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1687G>A p.V563M COSMIC PASSENGER/OTHER Possibly Damaging 449 1950530 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1741T>A p.W581R COSMIC CANCER Probably Damaging 450 1950531 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1920_1920delT p.F640fs*11 COSMIC NP NP 451 1950532 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1903C>T p.R635W COSMIC PASSENGER/OTHER Probably Damaging 452 1950533 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1904G>A p.R635Q COSMIC PASSENGER/OTHER Probably Damaging 453 1950534 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1896_1896delG p.K632fs*19 COSMIC NP NP 454 1950536 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2069T>G p.V690G COSMIC PASSENGER/OTHER Probably Damaging 455 1950537 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2062C>A p.R688S COSMIC PASSENGER/OTHER Probably Damaging 456 1950538 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1965_1965delT p.Q656fs*49 COSMIC NP NP 457 1950539 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1998_1998delT p.C666fs*39 COSMIC NP NP 458 1950540 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2043_2043delC p.M682fs*23 COSMIC NP NP 459 1950541 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2056G>T p.D686Y COSMIC CANCER Probably Damaging 460 1950542 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 461 1950543 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2172_2173insA p.E725fs*9 COSMIC NP NP 462 1950544 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2095G>A p.G699S COSMIC PASSENGER/OTHER Probably Damaging 463 1950545 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2147T>A p.V716D COSMIC PASSENGER/OTHER Probably Damaging 464 1950547 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2113A>T p.I705F COSMIC PASSENGER/OTHER Probably Damaging 465 1950548 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2150A>G p.N717S COSMIC PASSENGER/OTHER Probably Damaging 466 1950549 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2129G>C p.C710S COSMIC CANCER Probably Damaging 467 1950550 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2086_2086delC p.Q696fs*9 COSMIC NP NP 468 1950551 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 469 1950552 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2150A>G p.N717S COSMIC PASSENGER/OTHER Probably Damaging 470 1950553 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2114T>C p.I705T COSMIC PASSENGER/OTHER Probably Damaging 471 1950554 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2147T>A p.V716D COSMIC PASSENGER/OTHER Probably Damaging 472 1950555 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 473 1950556 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2150A>G p.N717S COSMIC PASSENGER/OTHER Probably Damaging 474 1950557 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 475 1950558 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 476 1950559 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2120G>T p.G707V COSMIC CANCER Probably Damaging 477 1950560 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2311C>G p.R771G COSMIC PASSENGER/OTHER Probably Damaging 478 1950561 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2309C>T p.S770L COSMIC PASSENGER/OTHER Probably Damaging 479 1950562 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2206C>T p.R736C COSMIC PASSENGER/OTHER Probably Damaging 480 1950563 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2309C>A p.S770* COSMIC NP NP 481 1950564 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2317C>A p.L773I COSMIC PASSENGER/OTHER Probably Damaging 482 1950566 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2318T>G p.L773R COSMIC PASSENGER/OTHER Probably Damaging 483 1950567 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2207G>A p.R736H COSMIC PASSENGER/OTHER Probably Damaging 484 1950569 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2193_2194insT p.E733fs*1 COSMIC NP NP 485 1950570 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2245C>T p.R749C COSMIC PASSENGER/OTHER Probably Damaging 486 1950571 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2272_2274delGTG p.V758del COSMIC NP NP 487 1950572 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2206C>T p.R736C COSMIC PASSENGER/OTHER Probably Damaging 488 1950574 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2185C>T p.R729W COSMIC PASSENGER/OTHER Probably Damaging 489 1950575 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2206C>T p.R736C COSMIC PASSENGER/OTHER Probably Damaging 490 1950576 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2204A>G p.Y735C COSMIC PASSENGER/OTHER Probably Damaging 491 1950577 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2302_2302delG p.D768fs*11 COSMIC NP NP 492 1950578 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2203T>A p.Y735N COSMIC PASSENGER/OTHER Probably Damaging 493 1950579 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2318T>C p.L773P COSMIC PASSENGER/OTHER Probably Damaging 494 1950580 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2193_2194insT p.E733fs*1 COSMIC NP NP 495 1950581 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2245C>T p.R749C COSMIC PASSENGER/OTHER Probably Damaging 496 1950582 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2189_2191delTCT p.F731del COSMIC NP NP 497 1950583 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2206C>T p.R736C COSMIC PASSENGER/OTHER Probably Damaging 498 1950584 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2339T>C p.I780T COSMIC CANCER Probably Damaging 499 1950585 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2344_2353del10 p.A782fs*17 COSMIC NP NP 500 1950586 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2409_2422del14 p.R803fs*4 COSMIC NP NP 501 1950587 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2456T>C p.L819P COSMIC CANCER Probably Damaging 502 1950588 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2477A>G p.K826R COSMIC CANCER Benign 503 1950589 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2578T>C p.W860R COSMIC CANCER Probably Damaging 504 1950590 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2553_2553delC p.F851fs*2 COSMIC NP NP 505 1950591 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2551_2552delTT p.F851fs*3 COSMIC NP NP 506 1950593 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2587G>A p.E863K COSMIC CANCER Probably Damaging 507 1950594 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 508 1950595 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 509 1950596 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 510 1950597 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2678G>C p.W893S COSMIC CANCER Probably Damaging 511 1950598 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 512 1950599 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 513 1950600 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 514 1950601 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 515 1950602 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 516 1950603 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 517 1950604 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 518 1950605 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 519 1950606 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 520 1950607 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 521 1950608 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 522 1950609 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 523 1950610 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 524 1950611 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 525 1950612 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 526 1950613 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 527 1950614 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 528 1950615 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 529 1950616 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 530 1950617 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 531 1950618 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 532 1950619 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 533 1950620 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 534 1950621 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 535 1950622 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 536 1950623 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 537 1950624 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 538 1950625 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 539 1950626 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 540 1950627 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 541 1950628 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 542 1950629 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 543 1950630 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 544 1950631 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 545 1950632 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 546 1950633 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 547 1950634 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 548 1950635 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 549 1950636 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 550 1950637 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 551 1950638 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 552 1950639 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 553 1950640 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 554 1950641 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 555 1950642 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 556 1950643 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 557 1950644 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 558 1950645 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 559 1950646 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 560 1950647 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 561 1950648 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 562 1950649 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 563 1950650 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 564 1950651 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 565 1950652 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 566 1950653 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 567 1950654 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 568 1950655 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 569 1950656 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 570 1950657 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 571 1950658 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 572 1950659 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 573 1950660 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2656C>G p.Q886E COSMIC CANCER Probably Damaging 574 1950661 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 575 1950662 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 576 1950663 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 577 1950664 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 578 1950665 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 579 1950666 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>T p.R882L COSMIC CANCER Probably Damaging 580 1950667 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 581 1950668 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 582 1950669 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 583 1950670 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 584 1950671 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 585 1950672 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 586 1950673 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 587 1950674 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 588 1950675 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2693T>C p.I898T COSMIC CANCER Possibly Damaging 589 1950676 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 590 1950677 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 591 1950678 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 592 1950679 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 593 1950680 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 594 1950681 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 595 1950682 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 596 1950683 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 597 1950684 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 598 1950685 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2602T>G p.F868V COSMIC CANCER Probably Damaging 599 1950686 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 600 1950687 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 601 1950688 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 602 1950689 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 603 1950690 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 604 1950691 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 605 1950692 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 606 1950693 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 607 1950694 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 608 1950695 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 609 1950696 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 610 1950697 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 611 1950698 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 612 1950699 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 613 1950700 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 614 1950701 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 615 1950702 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 616 1950703 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 617 1950704 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 618 1950705 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 619 1950706 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 620 1950707 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 621 1950708 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 622 1950709 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 623 1950710 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 624 1950711 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 625 1950712 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 626 1950713 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 627 1950714 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 628 1950715 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 629 1950716 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 630 1950717 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 631 1950718 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2612C>T p.P871L COSMIC CANCER Probably Damaging 632 1950719 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 633 1950720 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 634 1950721 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 635 1950722 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 636 1950723 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 637 1950724 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 638 1950725 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 639 1950726 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 640 1950727 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 641 1950728 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 642 1950729 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 643 1950730 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 644 1950731 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 645 1950732 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 646 1950733 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 647 1950734 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 648 1950735 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 649 1950736 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 650 1950737 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 651 1950738 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 652 1950739 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 653 1950740 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 654 1950741 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 655 1950742 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 656 1950743 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 657 1950744 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 658 1950745 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 659 1950746 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2710C>G p.P904A COSMIC CANCER Probably Damaging 660 1950747 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 661 1950748 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 662 1950749 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 663 1950750 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 664 1950751 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 665 1950752 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 666 1950753 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 667 1950754 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2696G>A p.R899H COSMIC CANCER Probably Damaging 668 1950755 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2635A>G p.N879D COSMIC CANCER Probably Damaging 669 1950756 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 670 1950757 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 671 1950758 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 672 1950759 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 673 1950760 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 674 1950761 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 675 1950762 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 676 1950763 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 677 1950764 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 678 1950765 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 679 1950766 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 680 1950767 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 681 1950768 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 682 1950769 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 683 1950770 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 684 1950771 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 685 1950772 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 686 1950773 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 687 1950774 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 688 1950775 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 689 1950776 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 690 1950777 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 691 1950778 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 692 1950779 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 693 1950780 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 694 1950781 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 695 1950782 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 696 1950783 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 697 1950784 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 698 1950785 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 699 1950786 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 700 1950787 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 701 1950788 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 702 1950789 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 703 1950790 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 704 1950791 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 705 1950792 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 706 1950793 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 707 1950794 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 708 1950795 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 709 1950796 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 710 1950797 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 711 1950798 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 712 1950799 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 713 1950800 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 714 1950801 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 715 1950802 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 716 1950803 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 717 1950804 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 718 1950805 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2706delC p.F902fs*4 COSMIC NP NP 719 1950806 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 720 1950807 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 721 1950808 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 722 1950809 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 723 1950810 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2711C>T p.P904L COSMIC CANCER Probably Damaging 724 1950811 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 725 1950812 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>G p.R882G COSMIC CANCER Probably Damaging 726 1950813 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 727 1950814 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 728 1950815 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 729 1950816 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 730 1950817 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 731 1950818 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 732 1950819 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 733 1950820 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 734 1950821 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 735 1950822 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 736 1950823 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 737 1950824 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 738 1950825 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 739 1950826 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 740 1950827 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 741 1950828 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 742 1950829 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 743 1950830 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 744 1950831 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 745 1950832 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 746 1950833 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 747 1950834 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 748 1950835 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 749 1950836 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 750 1950837 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 751 1950838 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 752 1950839 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 753 1950840 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 754 1950841 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1527_1528insT p.V510fs*36 COSMIC NP NP 755 1950842 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1661G>A p.C554Y COSMIC CANCER Probably Damaging 756 1950843 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2255T>G p.F752C COSMIC PASSENGER/OTHER Probably Damaging 757 1950843 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2311C>T p.R771* COSMIC NP NP 758 1950844 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1539G>A p.M513I COSMIC PASSENGER/OTHER Benign 759 1950844 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2504C>T p.T835M COSMIC CANCER Probably Damaging 760 1950845 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2309C>G p.S770W COSMIC PASSENGER/OTHER Probably Damaging 761 1950845 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2526G>T p.Q842H COSMIC CANCER Probably Damaging 762 1950846 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2204A>G p.Y735C COSMIC PASSENGER/OTHER Probably Damaging 763 1950846 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2486A>T p.K829I COSMIC CANCER Probably Damaging 764 1950847 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1648G>A p.G550R COSMIC PASSENGER/OTHER Probably Damaging 765 1950847 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2375G>A p.R792H COSMIC CANCER Probably Damaging 766 1950848 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1626G>T p.G542G COSMIC NP NP 767 1950848 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1627G>T p.G543C COSMIC PASSENGER/OTHER Probably Damaging 768 1950849 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1988C>T p.S663L COSMIC PASSENGER/OTHER Probably Damaging 769 1950849 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2711C>T p.P904L COSMIC CANCER Probably Damaging 770 1950850 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1945_1963>CG p.V649fs*13 COSMIC NP NP 771 1950850 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2711C>T p.P904L COSMIC CANCER Probably Damaging 772 1950851 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2153C>G p.P718R COSMIC PASSENGER/OTHER Probably Damaging 773 1950851 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 774 1950852 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2150A>G p.N717S COSMIC PASSENGER/OTHER Probably Damaging 775 1950852 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2628C>A p.D876E COSMIC CANCER Probably Damaging 776 1950853 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2308_2309insCG p.F772fs*8 COSMIC NP NP 777 1950853 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 778 1950854 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2678G>T p.W893L COSMIC CANCER Probably Damaging 779 1950854 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2679G>C p.W893C COSMIC CANCER Probably Damaging 780 2025223 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 781 2025224 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 782 2025225 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 783 2025226 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 784 2025227 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 785 2025228 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 786 2025229 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 787 2025230 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 788 2025231 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>C p.R882P COSMIC CANCER Possibly Damaging 789 2025232 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2638A>G p.M880V COSMIC CANCER Possibly Damaging 790 2177 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2651C>T p.A884V COSMIC CANCER Probably Damaging 791 2181 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 792 2183 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 793 2185 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2409_2478del70 p.R803fs*5 COSMIC NP NP 794 2187 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 795 2188 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 796 2191 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 797 2195 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 798 2198 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2309C>T p.S770L COSMIC PASSENGER/OTHER Probably Damaging 799 2199 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2245C>T p.R749C COSMIC PASSENGER/OTHER Probably Damaging 800 2206 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 801 2225 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 802 2226 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 803 2229 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1904G>C p.R635P COSMIC PASSENGER/OTHER Probably Damaging 804 2231 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2580_2597del18 p.C861_R866del COSMIC NP NP 805 2234 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2312G>A p.R771Q COSMIC PASSENGER/OTHER Probably Damaging 806 2239 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1644G>A p.M548I COSMIC PASSENGER/OTHER Benign 807 2244 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 808 2255 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2378A>C p.Y793S COSMIC CANCER Probably Damaging 809 2256 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 810 2257 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 811 2261 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 812 2272 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1741T>C p.W581R COSMIC CANCER Probably Damaging 813 2282 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 814 2283 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 815 2284 LIVER c.1598A>G p.Y533C COSMIC PASSENGER/OTHER Probably Damaging 816 2289 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1640T>A p.L547H COSMIC PASSENGER/OTHER Probably Damaging 817 2291 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2605G>A p.G869S COSMIC CANCER Probably Damaging 818 2296 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 819 2300 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2057A>G p.D686G COSMIC CANCER Probably Damaging 820 2334195 LUNG c.76G>T p.G26* COSMIC NP NP 821 2334195 LUNG c.77G>T p.G26V COSMIC PASSENGER/OTHER Benign 822 2467 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 823 2541 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2134G>A p.D712N COSMIC PASSENGER/OTHER Probably Damaging 824 2541 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2353G>A p.V785M COSMIC CANCER Probably Damaging 825 2550 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1711_1711delG p.A571fs*80 COSMIC NP NP 826 2669 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 827 2672 LARGE INTESTINE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 828 2679 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 829 2683 LARGE INTESTINE c.2185C>T p.R729W COSMIC PASSENGER/OTHER Probably Damaging 830 2685 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 831 2687 LARGE INTESTINE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 832 2689 LARGE INTESTINE c.1627G>T p.G543C COSMIC PASSENGER/OTHER Probably Damaging 833 2692 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 834 2757 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 835 2771 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 836 3278 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 837 3310 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 838 3311 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1741T>A p.W581R COSMIC CANCER Probably Damaging 839 3321 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1994T>G p.V665G COSMIC PASSENGER/OTHER Probably Damaging 840 3331 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 841 3481 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 842 3483 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1502A>G p.N501S COSMIC PASSENGER/OTHER Benign 843 3483 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2407_2476del70 p.R803fs*5 COSMIC NP NP 844 3491 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2206C>T p.R736C COSMIC PASSENGER/OTHER Probably Damaging 845 4334 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2196_2197insT p.E733fs*1 COSMIC NP NP 846 452198 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 847 5285 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 848 5286 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2512A>G p.N838D COSMIC CANCER Probably Damaging 849 5349 LARGE INTESTINE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 850 5354 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1627G>T p.G543C COSMIC PASSENGER/OTHER Probably Damaging 851 5355 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1656_1663CAACTGCT>A p.N552fs*97 COSMIC NP NP 852 5362 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1903C>T p.R635W COSMIC PASSENGER/OTHER Probably Damaging 853 5363 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 854 587284 LARGE INTESTINE c.1058C>T p.A353V COSMIC PASSENGER/OTHER Benign 855 587342 LARGE INTESTINE c.1138G>A p.A380T COSMIC PASSENGER/OTHER Probably Damaging 856 6239 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1872_1872delA p.P625fs*26 COSMIC NP NP 857 6245 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 858 6366 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 859 6368 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2141C>G p.S714C COSMIC CANCER Probably Damaging 860 6369 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2729C>T p.A910V COSMIC CANCER Probably Damaging 861 6370 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 862 6371 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 863 6374 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2311C>T p.R771* COSMIC NP NP 864 6724 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 865 6732 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 866 6734 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1903C>T p.R635W COSMIC PASSENGER/OTHER Probably Damaging 867 6952 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 868 6979 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 869 7057 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 870 7065 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1713_1721del9 p.A572_A574del COSMIC NP NP 871 7067 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 872 7074 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1627G>T p.G543C COSMIC PASSENGER/OTHER Probably Damaging 873 7075 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 874 7078 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 875 7119 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 876 7120 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2203_2203delT p.Y735fs*44 COSMIC NP NP 877 7121 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 878 7122 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 879 7124 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 880 7131 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 881 7144 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1628G>T p.G543V COSMIC PASSENGER/OTHER Probably Damaging 882 7145 LUNG c.2311C>T p.R771* COSMIC NP NP 883 7153 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 884 7164 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 885 7167 LUNG c.2644C>T p.R882C COSMIC CANCER Probably Damaging 886 7168 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 887 7172 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 888 7186 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1903C>T p.R635W COSMIC PASSENGER/OTHER Probably Damaging 889 7188 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 890 7276 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 891 7309 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2171A>G p.Y724C COSMIC PASSENGER/OTHER Probably Damaging 892 7311 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 893 7313 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 894 7314 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2314T>A p.F772I COSMIC PASSENGER/OTHER Possibly Damaging 895 7316 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 896 7318 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 897 7319 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 898 7322 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 899 7324 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1685G>A p.C562Y COSMIC CANCER Probably Damaging 900 7324 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2146G>A p.V716I COSMIC PASSENGER/OTHER Benign 901 7327 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2578T>C p.W860R COSMIC CANCER Probably Damaging 902 7328 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 903 7407 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 904 7408 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 905 7411 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1776C>G p.Y592* COSMIC NP NP 906 7411 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2307_2308insT p.S770fs*12 COSMIC NP NP 907 7414 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 908 86319 LUNG c.480C>T p.S160S COSMIC NP NP 909 933124 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2168delT p.L723fs*56 COSMIC NP NP 910 BN23T LIVER c.2530A>G p.K844E COSMIC CANCER Probably Damaging 911 BN26T LIVER c.1816C>A p.Q606K COSMIC PASSENGER/OTHER Benign 912 CA1 LARGE INTESTINE c.558G>A p.P186P COSMIC NP NP 913 CLL007 HAEMATOPOIETIC AND LYMPHOID TISSUE c.457C>T p.Q153* COSMIC NP NP 914 CMML-02 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 915 EKVX LUNG c.2375G>A p.R792H COSMIC CANCER Probably Damaging 916 ESO-0061 OESOPHAGUS c.2066G>A p.S689N COSMIC PASSENGER/OTHER Benign 917 ESO-137 OESOPHAGUS c.2025G>A p.V675V COSMIC NP NP 918 ESO-864 OESOPHAGUS c.2172C>T p.Y724Y COSMIC NP NP 919 HCC97T LIVER c.1531G>T p.G511* COSMIC NP NP 920 HCT-15 LARGE INTESTINE c.2283G>A p.M761I COSMIC PASSENGER/OTHER Probably Damaging 921 HD-0719 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 922 HD-0880 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2245C>T p.R749C COSMIC PASSENGER/OTHER Probably Damaging 923 HD-1137 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>A p.R882S COSMIC CANCER Probably Damaging 924 HN_62506 UPPER AERODIGESTIVE TRACT c.2162A>G p.K721R COSMIC PASSENGER/OTHER Benign 925 HN_62995 UPPER AERODIGESTIVE TRACT c.2000A>C p.E667A COSMIC PASSENGER/OTHER Possibly Damaging 926 H_GV-933124G-S_9043 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2168delT p.L723fs*56 COSMIC NP NP 927 H_KA-452198-0814719 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 928 ID13 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2706delC p.F902fs*4 COSMIC NP NP 929 ID31 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 930 ID33 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 931 In-3 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2690T>A p.V897D COSMIC CANCER Probably Damaging 932 LAU50_2 SKIN c.2278G>C p.A760P COSMIC PASSENGER/OTHER Probably Damaging 933 LC_C9 LUNG c.149G>T p.R50L COSMIC PASSENGER/OTHER Probably Damaging 934 LUAD-B02216 LUNG c.1342_1343insT p.Y448fs*25 COSMIC NP NP 935 LUAD-B02216 LUNG c.2683G>A p.V895M COSMIC CANCER Probably Damaging 936 MDS-19 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1627G>T p.G543C COSMIC PASSENGER/OTHER Probably Damaging 937 MN-294 MENINGES c.1237G>A p.G413S COSMIC PASSENGER/OTHER Probably Damaging 938 Malme-3M HAEMATOPOIETIC AND LYMPHOID TISSUE c.2158C>T p.R720C COSMIC PASSENGER/OTHER Probably Damaging 939 Malme-3M HAEMATOPOIETIC AND LYMPHOID TISSUE c.2571delC p.D857fs*24 COSMIC NP NP 940 NCI-H23 LUNG c.667G>T p.G223* COSMIC NP NP 941 OCI-AML2 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1903C>T p.R635W COSMIC PASSENGER/OTHER Probably Damaging 942 OCI-AML3 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 943 P1 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 944 P7 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1769delG p.G590fs*61 COSMIC NP NP 945 PD4176a HAEMATOPOIETIC AND LYMPHOID TISSUE c.2275_2276insT p.A760fs*5 COSMIC NP NP 946 PD4179a HAEMATOPOIETIC AND LYMPHOID TISSUE c.2095G>A p.G699S COSMIC PASSENGER/OTHER Probably Damaging 947 PD4182a HAEMATOPOIETIC AND LYMPHOID TISSUE c.2250delC p.F751fs*28 COSMIC NP NP 948 PD6358a NS c.1717_1725delCAGGCAGCC p.Q573_A575delQAA COSMIC NP NP 949 RK098_C01 LIVER c.396G>A p.V132V COSMIC NP NP 950 RK141_C01 LIVER c.1424C>T p.T475I COSMIC PASSENGER/OTHER Benign 951 TCGA-04-1361-01 OVARY c.2728G>A p.A910T COSMIC CANCER Probably Damaging 952 TCGA-13-0924-01 OVARY c.1241T>C p.F414S COSMIC PASSENGER/OTHER Probably Damaging 953 TCGA-13-1497-01 OVARY c.2209C>T p.L737F COSMIC PASSENGER/OTHER Probably Damaging 954 TCGA-18-3414-01 LUNG c.1598A>G p.Y533C COSMIC PASSENGER/OTHER Probably Damaging 955 TCGA-18-3416-01 LUNG c.1455G>C p.Q485H COSMIC PASSENGER/OTHER Benign 956 TCGA-18-4086-01 LUNG c.1596C>T p.G532G COSMIC NP NP 957 TCGA-22-5492-01 LUNG c.2039A>G p.K680R COSMIC PASSENGER/OTHER Benign 958 TCGA-33-4532-01 LUNG c.144G>T p.V48V COSMIC NP NP 959 TCGA-33-6737-01 LUNG c.2312G>A p.R771Q COSMIC PASSENGER/OTHER Probably Damaging 960 TCGA-34-2596-01 LUNG c.2632T>C p.S878P COSMIC CANCER Probably Damaging 961 TCGA-35-3615-01 LUNG c.2410C>T p.P804S COSMIC CANCER Possibly Damaging 962 TCGA-35-4123-01 LUNG c.1229C>T p.A410V COSMIC PASSENGER/OTHER Probably Damaging 963 TCGA-36-2530-01 OVARY c.226C>T p.P76S COSMIC PASSENGER/OTHER Benign 964 TCGA-37-3789-01 LUNG c.2375G>A p.R792H COSMIC CANCER Probably Damaging 965 TCGA-44-7662-01 LUNG c.79G>T p.E27* COSMIC NP NP 966 TCGA-50-5931-01 LUNG c.772G>A p.V258M COSMIC PASSENGER/OTHER Possibly Damaging 967 TCGA-50-6595-01 LUNG c.979T>G p.W327G COSMIC PASSENGER/OTHER Probably Damaging 968 TCGA-55-6987-01 LUNG c.2341G>C p.D781H COSMIC CANCER Probably Damaging 969 TCGA-55-8089-01 LUNG c.2006C>G p.S669C COSMIC PASSENGER/OTHER Probably Damaging 970 TCGA-64-5774-01 LUNG c.1481_1482GC>CT p.C494S COSMIC PASSENGER/OTHER Probably Damaging 971 TCGA-64-5778-01 LUNG c.935C>T p.S312F COSMIC PASSENGER/OTHER Probably Damaging 972 TCGA-85-6561-01 LUNG c.558G>T p.P186P COSMIC NP NP 973 TCGA-97-7547-01 LUNG c.2171A>G p.Y724C COSMIC PASSENGER/OTHER Probably Damaging 974 TCGA-A6-5666-01 LARGE INTESTINE c.1240T>C p.F414L COSMIC PASSENGER/OTHER Probably Damaging 975 TCGA-A6-6781-01 LARGE INTESTINE c.2713C>T p.L905L COSMIC NP NP 976 TCGA-AA-3543-01 LARGE INTESTINE c.2729C>T p.A910V COSMIC CANCER Probably Damaging 977 TCGA-AA-3662-01 LARGE INTESTINE c.1903C>T p.R635W COSMIC PASSENGER/OTHER Probably Damaging 978 TCGA-AA-3663-01 LARGE INTESTINE c.1433G>A p.R478Q COSMIC PASSENGER/OTHER Benign 979 TCGA-AA-3672-01 LARGE INTESTINE c.327delG p.Q110fs*52 COSMIC NP NP 980 TCGA-AA-3715-01 LARGE INTESTINE c.327_328insG p.Q110fs*14 COSMIC NP NP 981 TCGA-AA-3833-01 LARGE INTESTINE c.1179T>C p.S393S COSMIC NP NP 982 TCGA-AA-3833-01 LARGE INTESTINE c.841G>A p.E281K COSMIC PASSENGER/OTHER Benign 983 TCGA-AA-A00J-01 LARGE INTESTINE c.700G>A p.G234R COSMIC PASSENGER/OTHER Benign 984 TCGA-AA-A01Q-01 LARGE INTESTINE c.562C>A p.L188I COSMIC PASSENGER/OTHER Benign 985 TCGA-AB-2809-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 986 TCGA-AB-2818-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2409G>C p.R803S COSMIC CANCER Probably Damaging 987 TCGA-AB-2824-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2207G>A p.R736H COSMIC PASSENGER/OTHER Probably Damaging 988 TCGA-AB-2825-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 989 TCGA-AB-2839-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1543C>T p.Q515* COSMIC NP NP 990 TCGA-AB-2851-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1845delG p.E616fs*35 COSMIC NP NP 991 TCGA-AB-2861-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1843C>T p.Q615* COSMIC NP NP 992 TCGA-AB-2863-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 993 TCGA-AB-2867-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1403A>G p.K468R COSMIC PASSENGER/OTHER Benign 994 TCGA-AB-2867-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2486A>G p.K829R COSMIC CANCER Probably Damaging 995 TCGA-AB-2887-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2153C>T p.P718L COSMIC PASSENGER/OTHER Probably Damaging 996 TCGA-AB-2891-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2186G>A p.R729Q COSMIC PASSENGER/OTHER Probably Damaging 997 TCGA-AB-2898-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2375G>A p.R792H COSMIC CANCER Probably Damaging 998 TCGA-AB-2912-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2185C>T p.R729W COSMIC PASSENGER/OTHER Probably Damaging 999 TCGA-AB-2919-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1490G>A p.C497Y COSMIC PASSENGER/OTHER Probably Damaging 1000 TCGA-AB-2928-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2342A>G p.D781G COSMIC CANCER Probably Damaging 1001 TCGA-AB-2928-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.958C>T p.R320* COSMIC NP NP 1002 TCGA-AB-2938-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.943delA p.M315fs*1 COSMIC NP NP 1003 TCGA-AB-2965-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 1004 TCGA-AB-2966-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1769delG p.G590fs*61 COSMIC NP NP 1005 TCGA-AB-2967-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1513G>T p.E505* COSMIC NP NP 1006 TCGA-AB-2968-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.1429G>T p.E477* COSMIC NP NP 1007 TCGA-AB-2968-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2222C>T p.A741V COSMIC PASSENGER/OTHER Possibly Damaging 1008 TCGA-AB-2969-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 1009 TCGA-AB-2974-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 1010 TCGA-AB-2981-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2644C>T p.R882C COSMIC CANCER Probably Damaging 1011 TCGA-AB-2987-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 1012 TCGA-AB-2988-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2726T>G p.F909C COSMIC CANCER Probably Damaging 1013 TCGA-AB-2993-03 HAEMATOPOIETIC AND LYMPHOID TISSUE c.2168delT p.L723fs*56 COSMIC NP NP 1014 TCGA-AD-6888-01 LARGE INTESTINE c.2140T>C p.S714P COSMIC CANCER Probably Damaging 1015 TCGA-AD-6965-01 LARGE INTESTINE c.137G>A p.R46Q COSMIC PASSENGER/OTHER Probably Damaging 1016 TCGA-AG-A002-01 LARGE INTESTINE c.2350G>T p.E784* COSMIC NP NP 1017 TCGA-AG-A002-01 LARGE INTESTINE c.2505G>A p.T835T COSMIC NP NP 1018 TCGA-AG-A02N-01 LARGE INTESTINE c.626G>A p.R209H COSMIC PASSENGER/OTHER Probably Damaging 1019 TCGA-AN-A0XT-01 BREAST c.2645G>A p.R882H COSMIC CANCER Possibly Damaging 1020 TCGA-AP-A056-01 ENDOMETRIUM c.2223G>A p.A741A COSMIC NP NP 1021 TCGA-AP-A059-01 ENDOMETRIUM c.1139C>T p.A380V COSMIC PASSENGER/OTHER Probably Damaging 1022 TCGA-AP-A0LM-01 ENDOMETRIUM c.1986C>A p.A662A COSMIC NP NP 1023 TCGA-AP-A0LM-01 ENDOMETRIUM c.2058C>T p.D686D COSMIC NP NP 1024 TCGA-AX-A05Y-01 ENDOMETRIUM c.2729C>T p.A910V COSMIC CANCER Probably Damaging 1025 TCGA-AX-A0J1-01 ENDOMETRIUM c.919C>T p.P307S COSMIC CANCER Probably Damaging 1026 TCGA-AY-6386-01 LARGE INTESTINE c.1240T>C p.F414L COSMIC PASSENGER/OTHER Probably Damaging 1027 TCGA-B4-5836-01 KIDNEY c.2159G>C p.R720P COSMIC PASSENGER/OTHER Probably Damaging 1028 TCGA-B5-A0JY-01 ENDOMETRIUM c.1006T>G p.F336V COSMIC PASSENGER/OTHER Probably Damaging 1029 TCGA-B5-A11E-01 ENDOMETRIUM c.899T>C p.L300P COSMIC PASSENGER/OTHER Probably Damaging 1030 TCGA-B5-A11U-01 ENDOMETRIUM c.542G>A p.R181H COSMIC PASSENGER/OTHER Probably Damaging 1031 TCGA-BG-A0MQ-01 ENDOMETRIUM c.1976G>A p.R659H COSMIC PASSENGER/OTHER Benign 1032 TCGA-BH-A18J-01 BREAST c.650A>C p.K217T COSMIC PASSENGER/OTHER Benign 1033 TCGA-BP-5181-01 KIDNEY c.868T>A p.F290I COSMIC PASSENGER/OTHER Probably Damaging 1034 TCGA-BS-A0U7-01 ENDOMETRIUM c.2028G>A p.R676R COSMIC NP NP 1035 TCGA-BS-A0UF-01 ENDOMETRIUM c.2312G>A p.R771Q COSMIC PASSENGER/OTHER Probably Damaging 1036 TCGA-CA-5796-01 LARGE INTESTINE c.2728G>T p.A910S COSMIC CANCER Possibly Damaging 1037 TCGA-CA-6717-01 LARGE INTESTINE c.15C>T p.P5P COSMIC NP NP 1038 TCGA-CM-4743-01 LARGE INTESTINE c.2308T>C p.S770P COSMIC PASSENGER/OTHER Probably Damaging 1039 TCGA-CM-4743-01 LARGE INTESTINE c.2646C>A p.R882R COSMIC NP NP 1040 TCGA-CM-6171-01 LARGE INTESTINE c.1385C>T p.A462V COSMIC PASSENGER/OTHER Benign 1041 TCGA-D5-6928-01 LARGE INTESTINE c.274G>A p.D92N COSMIC PASSENGER/OTHER Probably Damaging 1042 TCGA-D5-6930-01 LARGE INTESTINE c.1444G>A p.E482K COSMIC PASSENGER/OTHER Benign 1043 TCGA-D5-6930-01 LARGE INTESTINE c.575C>T p.A192V COSMIC PASSENGER/OTHER Probably Damaging 1044 TCGA-D8-A1JE-01 BREAST c.2669G>A p.G890D COSMIC CANCER Probably Damaging 1045 TCGA-DR-A0ZM-01 CERVIX c.428G>A p.R143Q COSMIC PASSENGER/OTHER Benign 1046 TCGA-EJ-5501-01 PROSTATE c.1689G>A p.V563V COSMIC NP NP 1047 TCGA-EJ-5518-01 PROSTATE c.1320G>A p.W440* COSMIC NP NP 1048 TCGA-EJ-5521-01 PROSTATE c.336C>T p.G112G COSMIC NP NP 1049 TCGA-G4-6310-01 LARGE INTESTINE c.2158C>T p.R720C COSMIC PASSENGER/OTHER Probably Damaging 1050 TCGA-G4-6588-01 LARGE INTESTINE c.912C>T p.S304S COSMIC NP NP 1051 TGH STOMACH c.427C>T p.R143* COSMIC NP NP 1052 YUGAFFE SKIN c.2054G>A p.G685E COSMIC PASSENGER/OTHER Probably Damaging 1053 cSCCP7 SKIN c.1291C>T p.P431S COSMIC PASSENGER/OTHER Possibly Damaging
*NP: Not Predicted -
Copy number variation and expression profile (+)
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Gene Essentiality Data (+)
Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.test -
Tertiary structure (+)
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Structure Domains (+)
1. PFAM Domains:Domain ID Domain Name Start Site End Site E-value PF00855 PWWP 291 374 7.5e-19 PB000343 Pfam-B_343 386 556 1.9e-07 PB004002 Pfam-B_4002 462 643 1.6e-14 PB000829 Pfam-B_829 532 649 1e-06 PF00145 DNA_methylase 634 767 7.3e-12 PB000071 Pfam-B_71 775 910 5.7e-52 2. Superfamily Domains:Domain ID Start Site End Site E-value 0045633 626 910 1.99e-41 0047802 283 424 2.35e-38 0037717 529 597 5.18e-04 -
Sequence Alignment (+)
Users must enabled the Java in their browser to see sequence alignments.
Users can also download Java from here.1. Sequence alignment with 1000 genome variations:
Click on button to get Sequence alignment with Coverage, Consensus and Quality 2. Sequence alignment with CCLE mutants:
Click on button to get Sequence alignment with Coverage, Consensus and Quality 3. Sequence alignment with COSMIC mutants:
Click on button to get Sequence alignment with Coverage, Consensus and Quality 4. Sequence alignment with homologus proteins:
Click on button to get Sequence alignment with Coverage, Consensus and Quality -
Sequence Profiles (+)
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Post Translational Modifications (+)
$x "); for($d=2;$d<$l777;$d++) { fwrite($FP6,$row6[$d]); fwrite($FP7,"$row6[$d] "); fwrite($FP6,"\t"); } fwrite($FP6,"\n"); fwrite($FP7,""); } fclose($FP6); echo""; } else{echo"
"; ##### table ##### $ptm_tr=file_get_contents("$dir/ptm"); if($ptm_tr != '') { echo"S. No. Position Amino acid Type Post translational modifications are not found!!";} ?> -
Other Databases Link (+)
Proteomics DB COSMIC Gene Atlas STRING PIR DNMT3A DNMT3A DNMT3A ENSP00000264709 Q9Y6K1 QuickGO HGNC Ensembl Genome Browser TreeFam UniProt Q9Y6K1 DNMT3A ENSP00000264709 DNMT3A Q9Y6K1 Expression Atlas Protein Atlas OMIM IntAct PharmGKB DNMT3A ENSP00000264709 602769 Q9Y6K1 PA27445
