A Database of Epigenetic Modifiers
Protein: EHMT1 |
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# | Cell Line/Tumor sample | Tissue of Origin | cDNA change | Protein change | Source | FATHMM Prediction | PolyPhen2 Prediction |
---|---|---|---|---|---|---|---|
1 | 2334192 | LUNG | c.2015G>A | p.G672E | COSMIC | CANCER | Benign |
2 | 587278 | LARGE INTESTINE | c.94G>A | p.A32T | COSMIC | NP | NP |
3 | 587342 | LARGE INTESTINE | c.2761T>C | p.Y921H | COSMIC | NP | NP |
4 | 587376 | LARGE INTESTINE | c.1858G>A | p.V620M | COSMIC | NP | NP |
5 | 587376 | LARGE INTESTINE | c.3433G>T | p.D1145Y | COSMIC | PASSENGER/OTHER | Probably Damaging |
6 | BB13T | BREAST | c.35C>T | p.A12V | COSMIC | NP | NP |
7 | BN24T | LIVER | c.1920G>A | p.T640T | COSMIC | NP | NP |
8 | DU-145 | PROSTATE | c.1557G>T | p.L519F | COSMIC | CANCER | Probably Damaging |
9 | ESO-0950 | OESOPHAGUS | c.2725G>A | p.D909N | COSMIC | NP | NP |
10 | ESO-173 | OESOPHAGUS | c.1649G>A | p.R550H | COSMIC | NP | NP |
11 | ESO-805 | OESOPHAGUS | c.3149G>A | p.R1050H | COSMIC | NP | NP |
12 | ESO-859 | OESOPHAGUS | c.2299A>G | p.N767D | COSMIC | NP | NP |
13 | H1672 | LUNG | c.2015G>A | p.G672E | COSMIC | CANCER | Benign |
14 | H2009 | LUNG | c.2293G>T | p.G765C | COSMIC | NP | NP |
15 | HCC2218 | BREAST | c.3425A>T | p.Y1142F | COSMIC | NP | NP |
16 | HCC60T | LIVER | c.745G>T | p.V249F | COSMIC | NP | NP |
17 | HN_00313 | UPPER AERODIGESTIVE TRACT | c.1027G>A | p.D343N | COSMIC | NP | NP |
18 | HN_63021 | UPPER AERODIGESTIVE TRACT | c.38G>C | p.G13A | COSMIC | CANCER | Benign |
19 | LC_C21 | LUNG | c.3677G>T | p.R1226L | COSMIC | NP | NP |
20 | LC_C9 | LUNG | c.1074G>T | p.Q358H | COSMIC | NP | NP |
21 | LC_C9 | LUNG | c.1700G>T | p.G567V | COSMIC | NP | NP |
22 | LC_S18 | LUNG | c.3641G>T | p.R1214L | COSMIC | NP | NP |
23 | LUAD-5V8LT | LUNG | c.2710G>T | p.V904L | COSMIC | NP | NP |
24 | LUAD-B02077 | LUNG | c.2297C>T | p.A766V | COSMIC | NP | NP |
25 | LUAD-CHTN-Z4716A | LUNG | c.3529G>C | p.V1177L | COSMIC | NP | Probably Damaging |
26 | LUAD-E01278 | LUNG | c.120G>A | p.K40K | COSMIC | NP | NP |
27 | LUAD-RT-S01702 | LUNG | c.3737C>T | p.A1246V | COSMIC | NP | NP |
28 | ME009T | SKIN | c.1378G>A | p.V460I | COSMIC | NP | NP |
29 | P01-28 | PROSTATE | c.2102C>T | p.P701L | COSMIC | CANCER | Benign |
30 | Pa08C | PANCREAS | c.1939C>G | p.P647A | COSMIC | NP | NP |
31 | S00836 | LUNG | c.116C>A | p.A39E | COSMIC | CANCER | Benign |
32 | SF539 | CENTRAL NERVOUS SYSTEM | c.1A>G | p.M1V | COSMIC | CANCER | Benign |
33 | SJMB008 | CENTRAL NERVOUS SYSTEM | c.3402C>T | p.A1134A | COSMIC | NP | NP |
34 | TCGA-05-4395-01 | LUNG | c.264C>G | p.V88V | COSMIC | NP | NP |
35 | TCGA-05-4405-01 | LUNG | c.988G>T | p.G330C | COSMIC | NP | NP |
36 | TCGA-13-2057-01 | OVARY | c.3045G>C | p.V1015V | COSMIC | NP | NP |
37 | TCGA-22-5477-01 | LUNG | c.485C>A | p.A162D | COSMIC | NP | NP |
38 | TCGA-24-1431-01 | OVARY | c.1848C>T | p.T616T | COSMIC | NP | NP |
39 | TCGA-38-4632-01 | LUNG | c.285C>G | p.I95M | COSMIC | NP | NP |
40 | TCGA-43-5668-01 | LUNG | c.230A>T | p.H77L | COSMIC | NP | NP |
41 | TCGA-44-3918-01 | LUNG | c.3743A>C | p.Q1248P | COSMIC | NP | NP |
42 | TCGA-46-3765-01 | LUNG | c.801G>T | p.L267L | COSMIC | NP | NP |
43 | TCGA-51-4079-01 | LUNG | c.3409C>T | p.R1137* | COSMIC | NP | NP |
44 | TCGA-60-2698-01 | LUNG | c.2333C>T | p.P778L | COSMIC | NP | NP |
45 | TCGA-69-7979-01 | LUNG | c.2913G>T | p.R971S | COSMIC | NP | NP |
46 | TCGA-86-6851-01 | LUNG | c.868C>G | p.H290D | COSMIC | NP | NP |
47 | TCGA-95-7039-01 | LUNG | c.1854G>A | p.S618S | COSMIC | NP | NP |
48 | TCGA-A2-A04U-01 | BREAST | c.2237T>G | p.L746R | COSMIC | NP | NP |
49 | TCGA-A2-A1FZ-01 | BREAST | c.3231G>A | p.A1077A | COSMIC | NP | NP |
50 | TCGA-A5-A0GD-01 | ENDOMETRIUM | c.745G>T | p.V249F | COSMIC | NP | NP |
51 | TCGA-A6-6781-01 | LARGE INTESTINE | c.950C>T | p.S317L | COSMIC | NP | NP |
52 | TCGA-A8-A09M-01 | BREAST | c.755C>T | p.A252V | COSMIC | NP | NP |
53 | TCGA-AA-3672-01 | LARGE INTESTINE | c.3439G>A | p.D1147N | COSMIC | NP | NP |
54 | TCGA-AA-3715-01 | LARGE INTESTINE | c.3095T>C | p.V1032A | COSMIC | NP | NP |
55 | TCGA-AA-3811-01 | LARGE INTESTINE | c.1161G>A | p.S387S | COSMIC | NP | NP |
56 | TCGA-AA-3968-01 | LARGE INTESTINE | c.3425A>G | p.Y1142C | COSMIC | NP | NP |
57 | TCGA-AA-A022-01 | LARGE INTESTINE | c.1014G>A | p.A338A | COSMIC | NP | NP |
58 | TCGA-AP-A051-01 | ENDOMETRIUM | c.2648C>T | p.A883V | COSMIC | NP | NP |
59 | TCGA-AP-A056-01 | ENDOMETRIUM | c.2416G>A | p.A806T | COSMIC | NP | NP |
60 | TCGA-AP-A059-01 | ENDOMETRIUM | c.1012G>A | p.A338T | COSMIC | NP | NP |
61 | TCGA-AP-A059-01 | ENDOMETRIUM | c.112G>A | p.A38T | COSMIC | NP | NP |
62 | TCGA-AP-A059-01 | ENDOMETRIUM | c.3003G>T | p.E1001D | COSMIC | NP | Benign |
63 | TCGA-AP-A059-01 | ENDOMETRIUM | c.3283G>A | p.A1095T | COSMIC | NP | NP |
64 | TCGA-AP-A0LM-01 | ENDOMETRIUM | c.1348G>A | p.E450K | COSMIC | NP | Benign |
65 | TCGA-AP-A0LM-01 | ENDOMETRIUM | c.3103G>A | p.D1035N | COSMIC | NP | NP |
66 | TCGA-AP-A0LM-01 | ENDOMETRIUM | c.3149G>A | p.R1050H | COSMIC | NP | NP |
67 | TCGA-AP-A0LM-01 | ENDOMETRIUM | c.531G>A | p.P177P | COSMIC | NP | NP |
68 | TCGA-AP-A0LV-01 | ENDOMETRIUM | c.745G>T | p.V249F | COSMIC | NP | NP |
69 | TCGA-AX-A0J1-01 | ENDOMETRIUM | c.176G>A | p.R59Q | COSMIC | NP | NP |
70 | TCGA-AX-A0J1-01 | ENDOMETRIUM | c.1777G>A | p.A593T | COSMIC | NP | NP |
71 | TCGA-AX-A0J1-01 | ENDOMETRIUM | c.2707G>A | p.A903T | COSMIC | NP | NP |
72 | TCGA-AX-A0J1-01 | ENDOMETRIUM | c.2759G>A | p.R920H | COSMIC | NP | NP |
73 | TCGA-AZ-4315-01 | LARGE INTESTINE | c.1182A>C | p.K394N | COSMIC | NP | NP |
74 | TCGA-AZ-6598-01 | LARGE INTESTINE | c.2025G>A | p.R675R | COSMIC | NP | NP |
75 | TCGA-AZ-6601-01 | LARGE INTESTINE | c.3450C>T | p.D1150D | COSMIC | NP | NP |
76 | TCGA-B5-A0JY-01 | ENDOMETRIUM | c.3417A>C | p.E1139D | COSMIC | NP | NP |
77 | TCGA-B5-A0JY-01 | ENDOMETRIUM | c.581G>A | p.R194Q | COSMIC | NP | NP |
78 | TCGA-B5-A0JY-01 | ENDOMETRIUM | c.886A>G | p.K296E | COSMIC | NP | NP |
79 | TCGA-B5-A11E-01 | ENDOMETRIUM | c.244G>A | p.D82N | COSMIC | NP | NP |
80 | TCGA-B5-A11Y-01 | ENDOMETRIUM | c.1067G>A | p.R356H | COSMIC | NP | NP |
81 | TCGA-BL-A0C8-01 | URINARY TRACT | c.3068G>A | p.R1023K | COSMIC | NP | NP |
82 | TCGA-BS-A0UJ-01 | ENDOMETRIUM | c.114T>C | p.A38A | COSMIC | NP | NP |
83 | TCGA-BS-A0UV-01 | ENDOMETRIUM | c.241G>A | p.D81N | COSMIC | NP | NP |
84 | TCGA-CK-6746-01 | LARGE INTESTINE | c.1796G>A | p.C599Y | COSMIC | NP | NP |
85 | TCGA-CK-6746-01 | LARGE INTESTINE | c.2398C>A | p.L800M | COSMIC | NP | NP |
86 | TCGA-D1-A103-01 | ENDOMETRIUM | c.1012G>A | p.A338T | COSMIC | NP | NP |
87 | TCGA-D1-A103-01 | ENDOMETRIUM | c.1284G>T | p.E428D | COSMIC | NP | NP |
88 | TCGA-D1-A103-01 | ENDOMETRIUM | c.2094G>A | p.S698S | COSMIC | NP | NP |
89 | TCGA-D1-A16N-01 | ENDOMETRIUM | c.761T>C | p.V254A | COSMIC | NP | NP |
90 | TCGA-D1-A17Q-01 | ENDOMETRIUM | c.2296G>A | p.A766T | COSMIC | NP | NP |
91 | TCGA-D5-6928-01 | LARGE INTESTINE | c.36A>G | p.A12A | COSMIC | NP | NP |
92 | TCGA-D8-A1XY-01 | BREAST | c.2004G>A | p.T668T | COSMIC | NP | NP |
93 | TCGA-D8-A27T-01 | BREAST | c.3043G>A | p.V1015M | COSMIC | NP | NP |
94 | TCGA-DK-A1A5-01 | URINARY TRACT | c.3042C>T | p.C1014C | COSMIC | NP | NP |
95 | TCGA-DK-A3IT-01 | URINARY TRACT | c.3669C>T | p.F1223F | COSMIC | NP | NP |
96 | TCGA-DS-A0VL-01 | CERVIX | c.1689C>G | p.F563L | COSMIC | NP | NP |
97 | TCGA-E2-A14P-01 | BREAST | c.3692A>G | p.K1231R | COSMIC | NP | NP |
98 | TCGA-EI-6507-01 | LARGE INTESTINE | c.182C>T | p.A61V | COSMIC | NP | NP |
99 | TCGA-EU-5904-01 | KIDNEY | c.1908C>T | p.A636A | COSMIC | NP | NP |
100 | TCGA-G4-6304-01 | LARGE INTESTINE | c.1642C>T | p.R548W | COSMIC | NP | NP |
101 | TCGA-G4-6586-01 | LARGE INTESTINE | c.3368A>T | p.E1123V | COSMIC | NP | NP |
102 | TCGA-G5-6641-01 | LARGE INTESTINE | c.2992G>A | p.V998M | COSMIC | NP | NP |
103 | WA54 | PROSTATE | c.3558G>T | p.Q1186H | COSMIC | NP | NP |
104 | YURUB | SKIN | c.20C>T | p.S7L | COSMIC | NP | NP |
105 | cSCCP7 | SKIN | c.2188_2189GG>AA | p.G730K | COSMIC | NP | NP |
106 | pfg016T | STOMACH | c.2246C>T | p.A749V | COSMIC | NP | NP |
Domain ID | Domain Name | Start Site | End Site | E-value |
PB003620 | Pfam-B_3620 | 29 | 124 | 0.00027 |
PB003400 | Pfam-B_3400 | 289 | 419 | 6.3e-06 |
PF00023 | Ank | 774 | 800 | 3e-06 |
PF12796 | Ank_2 | 810 | 903 | 2.2e-27 |
PF12796 | Ank_2 | 910 | 985 | 1.2e-13 |
PF05033 | Pre-SET | 1013 | 1118 | 4.6e-19 |
PF00856 | SET | 1137 | 1243 | 5.6e-27 |
Domain ID | Start Site | End Site | E-value |
0048228 | 1003 | 1258 | 2.07e-83 |
0053922 | 741 | 984 | 9.95e-72 |
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S. No. | Position | Amino acid | Type |
Proteomics DB | COSMIC | Gene Atlas | STRING | PIR |
EHMT1 | EHMT1 | EHMT1 | ENSP00000417980 | Q9H9B1 |
QuickGO | HGNC | Ensembl Genome Browser | TreeFam | UniProt |
Q9H9B1 | EHMT1 | ENSP00000417980 | EHMT1 | Q9H9B1 |
Expression Atlas | Protein Atlas | OMIM | IntAct | PharmGKB |
EHMT1 | ENSP00000417980 | 607001 | Q9H9B1 | PA134941393 |