dbEM

Protein: KMT2C

Mutation Data (+)

# Cell Line/Tumor sample Tissue of Origin cDNA change Protein change Source FATHMM Prediction PolyPhen2 Prediction

*NP: Not Predicted
Copy number variation and expression profile (+)

Expression and CNV data is not present for KMT2C!!
Gene Essentiality Data (+)

Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.

Gene essentiality data is not present in COLT database!!
Tertiary structure (+)

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Modelled Structure Structures available in PDB

2YSM, 2YUK, 3UVL, 4ERY,

1. PFAM Domains:

2. Superfamily Domains:

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1. Sequence alignment with 1000 genome variations:

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2. Mutants are not present in CCLE!!

4. Mutants are not present in COSMIC!!

4. Sequence alignment with homologus proteins:

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Modelled Structure	Structures available in PDB
	2YSM, 2YUK, 3UVL, 4ERY,