Browse Biomarkers Based on Biomarker Basis

This page shows data for Methylation Based biomarker basis.
Total Entries Retrieved: 216
IDBiomarkerBiomoleculeSubjectsRegulationTypeExperimentLevel of SignificanceSourcePMID
102 Methylation status of GSTP1 mRNA Humans Hypermethylated in Patients who relapsed Prognostic Time to Progression p<0.03 Tissue 16322291
103 Methylation status of GSTP1 mRNA Humans Hypermethylated in Patients who relapsed Prognostic Time to Progression P = 0.004 Tissue 16322291
104 Methylation status of APC mRNA Humans Hypermethylated in Patients who relapsed Prognostic Time to Progression P = 0.004 Tissue 16322291
105 Methylation status of GSTP1 mRNA Humans Hypermethylated in Patients who relapsed Prognostic Time to Progression P = 0.01 Tissue 16322291
106 Methylation status of Cyclin D2 + APC mRNA Humans Hypermethylated in Patients who relapsed Prognostic Time to Progression 0.01 Tissue 16322291
263 Methylation Status of NKX2-5 mRNA Humans Hypermethylated (2.7% normal vs 14% in Cancerous condition) Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
264 Methylation Status of CALSTN1 mRNA Humans Hypermethylated (2.5% normal vs 12.1% in Cancerous condition) Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
265 Methylation Status of SPOCK2 mRNA Humans Hypermethylated (7.5% normal vs 15.2% in Cancerous condition) Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
266 Methylation Status of NSE1 mRNA Humans Hypermethylated (10.3% normal vs 20.5% in Cancerous condition) Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
267 Methylation Status of SLC16A12 mRNA Humans Hypermethylated (9% normal vs 22% in Cancerous condition) Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
268 Methylation Status of FOXN4 mRNA Humans Hypermethylated (2.4% normal vs 4.3% in Cancerous condition) Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
269 Methylation Status of GALR2 mRNA Humans Hypermethylated (2% normal vs 4.3% in Cancerous condition) Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
270 Methylation Status of DPYS mRNA Humans Hypermethylated (24.2% normal vs 42.71% in Cancerous condition) Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
271 Methylation Status of (DPYS or NKX2-5) mRNA Humans Hypermethylated in Prostate Cancer Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
272 Methylation Status of (CALSTN1 or DYPS) mRNA Humans Hypermethylated in Prostate Cancer Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
273 Methylation Status of (NSE1 or DPYS) mRNA Humans Hypermethylated in Prostate Cancer Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
274 Methylation Status of (NSE1 or SPOCK2) mRNA Humans Hypermethylated in Prostate Cancer Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
275 Methylation Status of (SLC16A12 or DPYS) mRNA Humans Hypermethylated in Prostate Cancer Diagnostic prostate cancer Vs normal prostate p<0.05 Tissue 18446232
378 Methylation Status of RASSF1 Methylation Humans Hypermethylated in Prostate Cancer Diagnostic Benign vs. PCA p<0.05 Expressed Prostatic Secretion 18948370
380 Serum PSA + DRE + Methylation Status of RARB mRNA Humans Hypermethylated in Prostate Cancer Diagnostic Benign vs. PCA p<0.06 Expressed Prostatic Secretion 18948370
381 Serum PSA + DRE + Methylation Status of (GSTP1, APC, RARB, and RASSF1) mRNA Humans GSTP1, APC, RARB, and RASSF1 Hypermethylated in Prostate Cancer Diagnostic Benign vs. PCA p<0.01 Expressed Prostatic Secretion 18948370
382 Serum PSA + DRE + Methylation Status of RASSF1 mRNA Humans RASSF1 Hypermethylated in Prostate Cancer Diagnostic Benign vs. PCA p< 0.05 Expressed Prostatic Secretion 18948370
386 Serum PSA + DRE + Methylation Status of GSTP1 mRNA Humans Hypermethylated in Prostate Cancer Diagnostic (Benign Samples + Gleason sums < 7) Vs ≥ 7 p<0.05 Expressed Prostatic Secretion 18948370
387 Serum PSA + DRE + Methylation Status of APC mRNA Humans Hypermethylated in Prostate Cancer Diagnostic (Benign Samples + Gleason sums < 7) Vs ≥ 7 p<0.01 Expressed Prostatic Secretion 18948370
388 Serum PSA + DRE + Methylation Status of RARB mRNA Humans Hypermethylated in Prostate Cancer Diagnostic (Benign Samples + Gleason sums < 7) Vs ≥ 7 p<0.01 Expressed Prostatic Secretion 18948370
389 Serum PSA + DRE + Methylation Status of RASSF1 mRNA Humans Hypermethylated in Prostate Cancer Diagnostic (Benign Samples + Gleason sums < 7) Vs ≥ 7 p<0.05 Expressed Prostatic Secretion 18948370
390 Serum PSA + DRE + Methylation Status of (GSTP1, APC, RARB, and RASSF1) mRNA Humans GSTP1, APC, RARB, and RASSF1 Hypermethylated in Prostate Cancer Diagnostic (Benign Samples + Gleason sums < 7) Vs ≥ 7 p<0.05 Expressed Prostatic Secretion 18948370
410 Methylation Status of RARB2 Methylation Humans Methylated in Stage IV PCa Prognostic PCa stage I-III VS PCa Stage IV p=0.027 Serum 19131636
411 Methylation Status of GSTP1 Methylation Humans Methylated in Stage IV PCa Prognostic PCA stage I-III VS PCA Stage IV p=0.019 Serum 19131636
412 Methylation Status of GSTP1+RARB2 Methylation Humans Methylated in Stage IV PCa Prognostic PCA stage I-III VS PCA Stage IV p=0.019 Serum 19131636
438 Methylation Status of: Chromosome 20 open reading frame 103 (C20orf103); Homeobox D9 (HOXD9); Nuclear receptor subfamily, group A, member 2 (NR5A2); Distal-less homeobox 5 (DLX5); Iroquois homeobox 1 (IRX1); Spastic paraplegia 20 (SPG20); Transcription factor AP-2 alpha (TFAP2A); Wilms tumor 1 (WT1); SIX homeobox 6 (SIX6); Homeobox D4 (HOXD4) ; Transcription factor 7-like 1 (TCF7L1); Sonic hedgehog homolog (SHH); Protocadherin, gamma subfamily C,5 (PCDHG5); Methionine aminopeptidase 1D (MAP1D); Runt-related transcription factor 1 (RUNX1) Methylation Humans Hypermethylated in PCa: [Chromosome 20 open reading frame 103 (C20orf103) (3.7 fold); Homeobox D9 (HOXD9) (3.2 fold); Nuclear receptor subfamily, group A, member 2 (NR5A2) (3.1 fold); Distal-less homeobox 5 (DLX5) (3.7 fold); Iroquois homeobox 1 (IRX1) (3.0 fold); Spastic paraplegia 20 (SPG20) (3.0 fold); Transcription factor AP-2 alpha (TFAP2A) (2.9 fold); Wilms tumor 1 (WT1) (2.9 fold); SIX homeobox 6 (SIX6) (2.8 fold); Homeobox D4 (HOXD4) (2.7 fold) ; Transcription factor 7-like 1 (TCF7L1) (2.6 fold); Sonic hedgehog homolog (SHH) (2.5 fold) ; Protocadherin , gamma subfamily C,5 (PCDHG5) (2.4 fold); Methionine aminopeptidase 1D (MAP1D) (2.3 fold); Runt-related transcription factor 1 (RUNX1) (2.3 fold);] Diagnostic Cancer Vs Non Cancer p<0.05 Tissue 19283074
439 Methylation Status of: Ventral anterior homeobox 1 (VAX1); Homeobox D3 (HOXD3); CAP-GLY domain containing linker protein family (CLIP4); Calcium channel, voltage dependent, T-type, alpha 1G 2.0 subunit (CACNA1G) ; Glycoprotein V (GP5); Somatostatin receptor 1 (SSTR1); Methylthioadenosine phosporylase (MTAP); NK2 homeobox 2 (NKX2-2); Homeobox C11 (HOXC11); Ladybird homeobox 1 (LBX1); Motor neuron and pancreas homeobox 1 (MNX1); Glutamate receptor, metabotropic 1 (GRM1); LIM homeobox 9 (LHX9); Microtubule-associated protein tau (MAPT); Galactosidase, beta 1-like (GLB1L) Methylation Humans Hypermethylated in Progression (PP4): [Ventral anterior homeobox 1 (VAX1) (2.7 fold); Homeobox D3 (HOXD3) (2.3 fold); CAP-GLY domain containing linker protein family (CLIP4) (2.1 fold); Calcium channel, voltage dependent, T-type, alpha 1G 2.0 subunit (CACNA1G) (2.0 fold); Glycoprotein V (GP5) (1.9 fold); Somatostatin receptor 1 (SSTR1) (1.8 fold); Methylthioadenosine phosporylase (MTAP) (1.8 fold); NK2 homeobox 2 (NKX2-2) (1.7 fold); Homeobox C11 (HOXC11) (1.6 fold); Ladybird homeobox 1 (LBX1) (1.6 fold); Motor neuron and pancreas homeobox 1 (MNX1) (1.6 fold); Glutamate receptor, metabotropic 1 (GRM1) (1.6 fold); LIM homeobox 9 (LHX9) (1.6 fold); Microtubule-associated protein tau (MAPT) (1.5 fold); Galactosidase, beta 1-like (GLB1L) (1.5 fold)] Prognostic Gleason Score 6 (Pure pattern 3) vs Gleason Score 8 (Pure Pattern 4) p<0.05 Tissue 19283074
485 Methylation Status of GSTP1 or RASSF1A Methylation Humans HyperMethylated in PCa Diagnostic Prostate Cancer Vs No Tumor p<0.05 Urine 20632177
580 Methylation Status of [A4GALT; ADAM8; ALOX15B; BIK; CCK; CRCP; CTSC; CXCL2; CXCL3; CYBA; EIF4B; GSTM1 ; GSTM2; IGF2; LTF; MCAM; PDCD1; PDPN; PKMYT1; PPP1R3C; RAB32; RFTN1; SERPINB1; SLC16A5; SOCS1; TIMP3; TNF] Methylation Humans HyperMethylated in PCa ( Positive Fold change): [A4GALT(2.0 fold) ; ADAM8(3.9 fold); ALOX15B(5.1fold, 2.7 fold); BIK(2.6 fold); CCK(9.3 fold); CRCP(2.1fold); CTSC(3.7 fold); CXCL2(3.2 fold); CXCL3(3.0fold); CYBA(3.8 fold); EIF4B(3.5 fold); GSTM1 (20.5 fold); GSTM2(4.1 fold); IGF2(4.2 fold); LTF(2.1 fold); MCAM(2.7 fold); PDCD1(3.2 fold); PDPN(4.5 fold); PKMYT1(2.9 fold); PPP1R3C(8.2 fold) ; RAB32(3.3 fold); RFTN1(5.5 fold); SERPINB1(2.4 fold); SLC16A5(17.2fold, 4.2 fold); SOCS1(2.6 fold); TIMP3(2.2 fold); TNF(2.0 fold)] Diagnostic Tumor Vs Tumor Adjacent p=0.013 Tissue 21237555
581 Methylation Status of [ALDH1A3; NR4A2; PF4; RELB; SOCS1; TNFRSF1B; ZBTB11; ZNF365] Methylation Humans HypoMethylated in PCa: ( Negative Fold change): [ALDH1A3(2.6 fold); NR4A2(2.5 fold); PF4(3.4 fold); RELB(2.1 fold); SOCS1(8.2 fold); TNFRSF1B(3.0 fold); ZBTB11(2.9 fold); ZNF365(5.0 fold)] Diagnostic Tumor Vs Tumor Adjacent p=0.013 Tissue 21237555
702 Methylation Status of (RARB or GSTP1 or RASSF1) Methylation Humans Hypermethylated in Cancer Prognostic Methylation in Patients with PCa NA Urine 21822036
703 Methylation Status of RARB Methylation Humans Hypermethylated in Cancer Prognostic Methylation in Patients with PCa NA Tissue 21822036
704 Methylation Status of RARB Methylation Humans Hypermethylated in Gleason Score 7 (PMR>=50) Prognostic Gleason Score 6 Vs Gleason Score 7 p=0.01 Urine 21822036
721 Methylation Status of APC Methylation Humans Hypermethylated in PCa Diagnostic negative histology followed by a positive biopsy less than 24 months later NA Tissue 19755651
722 Methylation Status of RAR-2β Methylation Humans Hypermethylated in PCa Diagnostic negative histology followed by a positive biopsy less than 24 months later NA Tissue 19755651
723 Methylation Status of GST-Pi Methylation Humans Hypermethylated in PCa Diagnostic negative histology followed by a positive biopsy less than 24 months later NA Tissue 19755651
804 Methylation of GSTP1 Methylation Humans Hypermethylated in PCa Prognostic negative histology followed by a positive biopsy more than 24 months later NA Tissue 22077694
805 Methylation of APC Methylation Humans Hypermethylated in PCa Prognostic negative histology followed by a positive biopsy more than 24 months later P=0.012 Tissue 22077694
806 Methylation of GSTP1 + APC Methylation Humans Hypermethylated in PCa Prognostic negative histology followed by a positive biopsy more than 24 months later NA Tissue 22077694
821 Methylation Status of AIM1 Methylation Humans Decreased hypermethylation in progression Prognostic Time To Progression Univariate: p = 0.02 ; Multivariate: p = 0.05 Tissue 22127895
889 Methylation Status of TBX15 Methylation Humans Highly methylated in ERG positive fusion compared to ERG negative fusion Prognostic ERG positive fusion compared to ERG negative fusion in Prostate cancer p<0.01 Tissue 22452941
890 Methylation Status of HOXD3 Methylation Humans Highly methylated in ERG positive fusion compared to ERG negative fusion Prognostic ERG positive fusion compared to ERG negative fusion in Prostate cancer p<0.01 Tissue 22452941
891 Methylation Status of CYP26A1 Methylation Humans Highly methylated in ERG positive fusion compared to ERG negative fusion Prognostic ERG positive fusion compared to ERG negative fusion in Prostate cancer p≤0.041 Tissue 22452941
892 Methylation Status of HOXD3 Methylation Humans Differentially Expressed Prognostic Pathological Stage (pT2 Vs pT3/pT4) p=0.026 Tissue 22452941
893 Methylation Status of TBX15 Methylation Humans Differentially Expressed Prognostic Pathological Stage (pT2 Vs pT3/pT4) p=0.010 Tissue 22452941
894 Methylation Status of HOXD3 Methylation Humans Differentially Expressed Prognostic Gleason score as ≤ 7 Vs 8 and above p<0.001 Tissue 22452941
895 Methylation Status of TBX15 or HOXD3 Methylation Humans Differentially Expressed Prognostic Disease specific survival Vs no survival p=0.044 Tissue 22452941
921 Methylation Status Of A0X1; CYBA; EDG3; ELF4; EPB41L3; FLJ12056; FLJ90650; FLT4; GAS6; GRASP; GSTP1; HAAO; HIF3A; HOXC11; LEP; MGC39606; MOBKL2B; RAB34; RARb; RHCG; RND2; SLC34A2; SPATA6; TPM4; ZNF154 Methylation Humans Methylated in PCA: Diagnostic Tumor Vs Normal Tissues p<0.0001 Tissue 22589488
922 Methylation Status Of ACTL6B; AEBP1; AMID; CD8A; CRIP1; FLJ30934; FLNC; FMOD; FOXE3; GAS7; GDPD5; HS3ST2; LOC349136; NEUROG1; PLTP; PTGER2; RASGRF2; RUNX3; SIX6; SLC9A3; SPSB4; SRD5A2; SUSD3; SYT10; TMEM74 Methylation Humans Hypermethlated in recurrent prostate cancer : Prognostic recurrent prostate cancer Vs nonrecurrent cancer NA Tissue 22589488
923 Methylation Status Of CHST7; LMX1B; RAFTLIN; RASGRF2; TNFRSF10D; ZNF135 Methylation Humans Methylated with Clinical Recurrence Prognostic clinical recurrence Vs biochemical recurrence NA Tissue 22589488
924 Methylation Status Of ALPL; AMPH; BCDIN3; BCL11B; BRD4; C18orf34; DCAMKL1; FGF5; FLJ42486; JAM2; LHX9; LOC283537; LRAT; PDE4B; POU3F3; PTGS2; RASGRF2; SLC27A6; SLC03A1; SPSB4; STAT3; SYN2; TACR3; TIRAP; WNT11 Methylation Humans Methylated with Systemic Recurrence Prognostic systemic recurrence Vs local recurrence NA Tissue 22589488
925 Methylation Status Of HIF3A; HAAO; RARb; GSTP1 Methylation Humans Methylated with Systemic Recurrence Diagnostic Tumor Vs Normal Tissues p<0.0182 Tissue 22589488
926 Methylation Status Of CRIP1; RUNX3; HS3ST2; FLNC; RASGRF2 Methylation Humans Methylated in PCA: Prognostic recurrent prostate cancer Vs nonrecurrent cancer NA Tissue 22589488
927 Methylation Status Of PHLDA3; RASGRF2; TNFRSF10D; ZNF135 Methylation Humans Hypermethlated in recurrent prostate cancer : Prognostic clinical recurrence Vs biochemical recurrence NA Tissue 22589488
928 Methylation Status Of BCL11B; POU3F3; RASGRF2 Methylation Humans Methylated with Clinical Recurrence Prognostic systemic recurrence Vs local recurrence NA Tissue 22589488
1015 NA Methylation Humans Hypermethylation in PCa (Δ Log Intensity): []; Hypomethylated in PCa: (Δ Log intensity): [] Diagnostic Pca Tumor Vs Tumor Adjacent NA Tissue 23119026
1016 Aldehyde Oxidase 1 (AOX1) Methylation Humans Hypermethylation in PCa Diagnostic Pca Tumor Vs Tumor Adjacent p = 7.46 x10^-8 Tissue 23119026
1017 Spondin 2 (SPON2) Methylation Humans Hypermethylation in PCa Diagnostic Pca Tumor Vs Tumor Adjacent p = 2.1 x10^-14 Tissue 23119026
1038 Alanyl membrane aminopeptidase (ANPEP) Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs Non Malignant Tissue p=0.0023 Tissue 23322201
1039 Alanyl membrane aminopeptidase (ANPEP) Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs Non Malignant Tissue p=0.0025 Tissue 23322201
1073 Methylation Status of RASSF1A Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs Benign Prostatic Hyperplasia p<0.001 Tissue 23431474
1074 Methylation Status of APC Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs Benign Prostatic Hyperplasia p<0.001 Tissue 23431474
1075 Methylation Status of APC Methylation Humans Hypermethylated in early stages of PCa Prognostic Stage 1 & 2 Vs Stage 3 & 4 p<0.049 Tissue 23431474
1179 Methylation Status of BNC1 Methylation Humans Hypermethylated in PCa (β atleast ≥ 0.2) Diagnostic Prostate Cancer Vs Normal Prostate p =0.0476 Tissue 23896626
1180 Methylation Status of FZD1 Methylation Humans Hypermethylated in PCa (β atleast ≥ 0.2) Diagnostic Prostate Cancer Vs Normal Prostate p =0.0363 Tissue 23896626
1181 Methylation Status of SYN2 Methylation Humans Hypermethylated in PCa (β atleast ≥ 0.2) Diagnostic Prostate Cancer Vs Normal Prostate p =0.049 Tissue 23896626
1182 Methylation Status of ZNF783 Methylation Humans Hypermethylated in PCa (β atleast ≥ 0.2) Diagnostic Prostate Cancer Vs Normal Prostate p =0.011 Tissue 23896626
1183 Methylation Status of CYB5R2 Methylation Humans Hypermethylated in PCa (β atleast ≥ 0.2) Diagnostic Prostate Cancer Vs Normal Prostate p =0.0003 Tissue 23896626
1185 Methylation Status of AOX1 (High vs. Low) Methylation Humans Hypermethylated in Prostate Cancer Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1186 Methylation Status of AOX1 (as continous variable) Methylation Humans Hypermethylated in Prostate Cancer Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1187 Methylation Status of C1orf114 (as continous variable) Methylation Humans Lower Methylation in Patients with Longer Survival Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1188 Methylation Status of C1orf114 (High vs. Low) Methylation Humans Lower Methylation in Patients with Longer Survival Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1189 Methylation Status of GAS6 (as continous variable) Methylation Humans Hypermethylated in Prostate Cancer Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1190 Methylation Status of GSTP1 Methylation Humans Hypermethylated in Prostate Cancer Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1191 Methylation Status of HAPLN3 (as continous variable) Methylation Humans Hypermethylated in Prostate Cancer Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1192 Methylation Status of HAPLN3 (High vs. Low) Methylation Humans Hypermethylated in Prostate Cancer Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1193 Methylation Status of KLF8 (High vs. Low) Methylation Humans Hypermethylated in Prostate Cancer Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1194 Methylation Status of KLF8 (as continuous variable) Methylation Humans Hypermethylated in Prostate Cancer Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1195 Methylation Status of MOB3B Methylation Humans Hypermethylated in Prostate Cancer Prognostic Biochemical recurrence P < 0.001 Tissue 23918943
1196 Methylation Status of AOX1/C1orf114/HAPLN3 Methylation Humans Lower Methylation in Patients with Longer Survival Prognostic Biochemical recurrence NA Tissue 23918943
1197 Methylation Status of AOX1/C1orf114/HAPLN3 Methylation Humans Lower Methylation in Patients with Longer Survival Prognostic Biochemical recurrence NA Tissue 23918943
1213 Methylation Status of HIST1H4K Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs Normal Prostate p<0.0001 Urine 24065480
1218 Methylation Status of APC Methylation Humans Hypermethylated in patients with Biochemical Recurrence Prognostic Biochemical recurrence Vs No Biochemical Recurrence p=0.02 Tissue 24086370
1219 Methylation Status of GSTP1 Methylation Humans Hypermethylated in patients with Biochemical Recurrence Prognostic Biochemical recurrence Vs No Biochemical Recurrence p=0.02 Serum 24086370
1398 Methylation status of GABRE + miR-224 +miR-452 miRNA + Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs Non Malignant p=0.001 Tissue 24737792
1399 Methylation status of GABRE + miR-224 +miR-452 (as continous value ) miRNA + Methylation Humans Hypermethylated in PCa Prognostic Biochemical recurrence Vs No Biochemical Recurrence Cohort 1: Univariate: p<0.001; Multivariate: p= 0.019 Cohort 2: Univariate: p<0.001; Multivariate: p=0.008 Tissue 24737792
1400 Methylation status of GABRE + miR-224 +miR-452 (High vs. Low ) miRNA + Methylation Humans Hypermethylated in PCa Prognostic Biochemical recurrence Vs No Biochemical Recurrence Cohort 1: Univariate: p<0.001; Multivariate: p= 0.019 Cohort 2: Univariate: p<0.001; Multivariate: p=0.008 Tissue 24737792
1444 Methylation status of genes (GSTM2; GSTP1; RARB; ALOX12; APC; PDGFRB; SCGB3A1; CFTR; MT1A; PENK; TERT; CCNA1; RARA; TAL1; ERG; MET; GFI1; MYCL2; SEPT9; COL18A1; KLK10; MFAP4; MMP14; TBX1; EYA4; NEU1; POMC; GADD45A; HTR1B; RASSF1; CDH13; PDGFRA; IRAK3; ASCL2; ESR1; HFE; IGFBP7; RARRES1; CAV1; THY1; BMP4;) Methylation Humans Hypermethylated in Pca Diagnostic Prostate Cancer Vs Normal Prostate NA Tissue 24961912
1599 Methylation Status of IL-6 Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs No Prostate Cancer p=0.03 Blood 26265203
1600 Methylation Status of ICAM-1 Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs No Prostate Cancer p=0.02 Blood 26265203
1601 Methylation Status of IFN Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs No Prostate Cancer p=0.02 Blood 26265203
1724 CRIP3 Methylation Humans Upregulated in PCa Prognostic Reclassification (Progression Vs No Progression) p=0.017 Urine 30777394
1733 Methylation Status of cg12799885 Methylation Humans Differentially Expressed [Log Fold Change: EMX2OS: (-5.98142); LINC02137 (-5.28623); LINC01116 (-3.59594); LINC00839: (- 4.30616); AL161645.1: (-4.9543); AC012123.1: (-4.63826); AL354793.1 (-5.45876); LINC02385: (-5.3465); HOXB‐AS3 (-5.22943); AC005674.1: (-3.98991);] Diagnostic Prostate Cancer Vs No Prostate Cancer p < 0.001 Tissue 30866497
1734 Methylation Status of DOCK2 Methylation Humans Differentially Expressed [Log Fold Change: hsa‐mir‐891a (-4.8); hsa‐mir‐892a (-5.14); hsa‐mir‐1224 (-3.66); hsa‐mir‐93 (1.79); hsa‐mir‐23c (-2.96); hsa‐mir‐1251 (-2.76); hsa‐mir‐204 (-1.84); hsa‐mir‐323b (-2.31); hsa‐mir‐200c (1.58); hsa‐mir‐96 (1.98);] Diagnostic Prostate Cancer Vs No Prostate Cancer p < 0.001 Tissue 30866497
1735 Methylation Status of FBXO30 Methylation Humans Differentially Expressed [Log Fold Change: SERPINA5: (-6.78954); MFSD2A (− 5.97025); ACSL6: (− 4.99597); MCF2: (−5.26855); EMX2: (− 6.79059); HOXB8: (− 6.24965); CLDN2: (−7.91887); AKR1B1: (− 3.87736); SPINK2: (−7.41992); CYP19A1: (−5.40444;] Diagnostic Prostate Cancer Vs No Prostate Cancer p < 0.001 Tissue 30866497
1736 Methylation Status of GRASP Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs No Prostate Cancer p < 0.001 Tissue 30866497
1737 Methylation Status of HIF3A Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs No Prostate Cancer p < 0.001 Tissue 30866497
1738 Methylation Status of MOB3B Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs No Prostate Cancer p < 0.001 Tissue 30866497
1739 Methylation Status of PFKP Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs No Prostate Cancer p < 0.001 Tissue 30866497
1740 Methylation Status of TPM4 Methylation Humans Hypermethylated in PCa Diagnostic Prostate Cancer Vs No Prostate Cancer p < 0.001 Tissue 30866497
1741 Methylation Status of cg12799885 Methylation Humans Hypermethylated in PCa Prognostic Biochemical recurrence Vs No Biochemical Recurrence Univariate: p=0.025 Tissue 30866497
1742 Methylation Status of DOCK2 Methylation Humans Hypermethylated in PCa Prognostic Biochemical recurrence Vs No Biochemical Recurrence Univariate: p < 0.001; Multivariate: p=0.004 Tissue 30866497
1743 Methylation Status of GRASP Methylation Humans Hypermethylated in PCa Prognostic Biochemical recurrence Vs No Biochemical Recurrence Univariate: p < 0.001; Multivariate: p=0.037 Tissue 30866497
1744 Methylation Status of HIF3A Methylation Humans NA Prognostic Biochemical recurrence Vs No Biochemical Recurrence Univariate: p=0.005 Multivariate: p =0.027 Tissue 30866497
1745 Methylation Status of PFKP Methylation Humans NA Prognostic Biochemical recurrence Vs No Biochemical Recurrence Univariate: p=0.001 Multivariate: p=0.028 Tissue 30866497
1746 Methylation Status of TPM4 Methylation Humans NA Prognostic Biochemical recurrence Vs No Biochemical Recurrence Univariate: p=0.038; Tissue 30866497
1813 APC; HOXD3; TGFβ2; GSTP1; KLK10 Methylation Humans NA Diagnostic Prostate Cancer Vs Benign p<0.05 Urine 30470249
1814 APC Methylation Humans NA Diagnostic Benign Vs High CAPRA Score p<0.01 Urine 30470249
1815 HOXD3 Methylation Humans NA Diagnostic Benign Vs High CAPRA Score p<0.01 Urine 30470249
1816 TGFβ2 Methylation Humans Methylated in PCa Diagnostic Benign Vs High CAPRA Score p<0.05 Urine 30470249
1817 GSTP1 Methylation Humans Methylated in PCa Diagnostic Benign Vs High CAPRA Score p<0.01 Urine 30470249
1818 KLK10 Methylation Humans Methylated in PCa Diagnostic Benign Vs High CAPRA Score p<0.001 Urine 30470249
1819 TBX15 Methylation Humans Methylated in PCa Diagnostic Benign Vs High CAPRA Score p<0.05 Urine 30470249
1820 HOXD3+GSTP1 Methylation Humans Methylated in PCa Diagnostic Benign Vs High CAPRA Score p<0.001 Urine 30470249
1860 Promoter methylation of: miR-193b+ miR-34b/c Methylation Humans Upregulated in Recurrent PCa Diagnostic Prostate Cancer Vs Controls p<0.05 Tissue 30373654
1861 Methlyation Status of APC, GSTP1 RARβ2 Methylation Humans Upregulated in PCa (Non PCa: 1504.7 Vs PCa: 1657.1) Diagnostic Prostate Cancer Vs Controls p<0.05 Tissue 30373654
1862 Promoter methylation of: miR-193b+ miR-34b/c Methylation Humans Upregulated in PCa (Non PCa: 1504.7 Vs PCa: 1657.1) Diagnostic Prostate Cancer Vs Controls p<0.05 Urine 30373654
1863 Methlyation Status of APC, GSTP1 RARβ2 Methylation Humans Methylated in PCa Diagnostic Prostate Cancer Vs Controls p<0.05 Urine 30373654
1864 Methlyation Status of APC, GSTP1 RARβ2 Methylation Humans Methylated in PCa Diagnostic Prostate Cancer Vs Controls p<0.05 Urine 30373654
1865 Methlyation Status of APC Methylation Humans Methylated in PCa Prognostic Gleason Grade 1 Vs Gleason Grade 2-5 p<0.01 Tissue 30373654
1866 Methlyation Status of GSTP1 Methylation Humans Methylated in PCa Prognostic Gleason Grade 1 Vs Gleason Grade 2-5 p<0.01 Tissue 30373654
1867 Methlyation Status of RARβ2 Methylation Humans Methylated in PCa Prognostic Gleason Grade 1 Vs Gleason Grade 2-5 p<0.01 Tissue 30373654
1868 Methlyation Status of miR-34b/c Methylation Humans Methylated in Gleason Grade 2-5 Prognostic Gleason Grade 1 Vs Gleason Grade 2-5 p<0.01 Tissue 30373654
1869 Methlyation Status of APC Methylation Humans Methylated in Gleason Grade 2-5 Prognostic Low & Intermediate Risk Vs High Risk p<0.01 Tissue 30373654
1870 Methlyation Status of APC Methylation Humans Methylated in Gleason Grade 2-5 Prognostic Low & Intermediate Risk Vs High Risk p<0.05 Tissue 30373654
1871 Promoter methylation of: miR-193b+ miR-34b/c Methylation Humans Methylated in Gleason Grade 2-5 Prognostic Prostate Cancer Specific Survival Vs No Survival p=0.017 Tissue 30373654
1872 Methlyation Status of APC Methylation Humans Methylated in High Risk Prognostic Biochemical Recurrence Vs No Biochemical Recurrence p=0.044 Tissue 30373654
1873 Promoter methylation of: GSTP1 Methylation Humans Methylated in High Risk Prognostic Biochemical Recurrence Vs No Biochemical Recurrence p=0.017 Tissue 30373654
1874 Methlyation Status of miR-34b/c Methylation Humans Methylated in PCa Prognostic Biochemical Recurrence Vs No Biochemical Recurrence p=0.017 Tissue 30373654
1943 Methylation status of A0X1 Methylation Humans Upregulated in PCa [mean PC/mean]: (2.34 fold) Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1944 Methylation status of CYBA Methylation Humans Upregulated in PCa [mean PC/mean]: (2.34 fold) Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1945 Methylation status of EDG3 Methylation Humans Upregulated in PCa [mean PC/mean]: (2.34 fold) Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1946 Methylation status of ELF4 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1947 Methylation status of EPB41L3 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1948 Methylation status of FLJ12056 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1949 Methylation status of FLJ90650 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1950 Methylation status of FLT4 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1951 Methylation status of GAS6 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1952 Methylation status of GRASP Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1953 Methylation status of GSTP1 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1954 Methylation status of HAAO Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1955 Methylation status of HIF3A Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1956 Methylation status of HOXC11 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1957 Methylation status of LEP Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1958 Methylation status of MGC39606 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1959 Methylation status of MOBKL2B Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1960 Methylation status of RAB34 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1961 Methylation status of RARb Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1962 Methylation status of RHCG Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1963 Methylation status of RND2 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1964 Methylation status of SLC34A2 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1965 Methylation status of SPATA6 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1966 Methylation status of TPM4 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1967 Methylation status of ZNF154 Methylation Humans Differentially Methylated between PCa and Normal Diagnostic Tumor Vs Normal Tissues <0.0001 Tissue 22589488
1968 Methylation status of ACTL6B Methylation Humans Differentially Methylated between PCa and Normal Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1969 Methylation status of AEBP1 Methylation Humans Differentially Methylated between PCa and Normal Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0021 Tissue 22589488
1970 Methylation status of AMID Methylation Humans Differentially Methylated between PCa and Normal Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1971 Methylation status of CD8A Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1972 Methylation status of CRIP1 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0037 Tissue 22589488
1973 Methylation status of FLJ30934 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1974 Methylation status of FLNC Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1975 Methylation status of FMOD Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1976 Methylation status of FOXE3 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1977 Methylation status of GAS7 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1978 Methylation status of GDPD5 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1979 Methylation status of HS3ST2 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1980 Methylation status of LOC349136 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1981 Methylation status of NEUROG1 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1982 Methylation status of PLTP Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1983 Methylation status of PTGER2 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1984 Methylation status of RASGRF2 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1985 Methylation status of RUNX3 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1986 Methylation status of SIX6 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1987 Methylation status of SLC9A3 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1988 Methylation status of SPSB4 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0008 Tissue 22589488
1989 Methylation status of SRD5A2 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1990 Methylation status of SUSD3 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0014 Tissue 22589488
1991 Methylation status of SYT10 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0001 Tissue 22589488
1992 Methylation status of TMEM74 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Recurrent prostate cancer Vs nonrecurrent cancer <0.0005 Tissue 22589488
1993 Methylation status of CHST7 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Clinical recurrence vs. biochemical recurrence <0.0050 Tissue 22589488
1994 Methylation status of LMX1B Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Clinical recurrence vs. biochemical recurrence <0.0021 Tissue 22589488
1995 Methylation status of PHLDA 3 Methylation Humans Hypermethlated in Recurrent prostate cancer Prognostic Clinical recurrence vs. biochemical recurrence <0.0772 Tissue 22589488
1996 Methylation status of RAFTLIN Methylation Humans Differentially Methylated in Clinical recurrence Prognostic Clinical recurrence vs. biochemical recurrence <0.0050 Tissue 22589488
1997 Methylation status of RASGRF2 Methylation Humans Differentially Methylated in Clinical recurrence Prognostic Clinical recurrence vs. biochemical recurrence <0.0015 Tissue 22589488
1998 Methylation status of TNFRSF10D Methylation Humans Differentially Methylated in Clinical recurrence Prognostic Clinical recurrence vs. biochemical recurrence <0.0008 Tissue 22589488
1999 Methylation status of ZNF135 Methylation Humans Differentially Methylated in Clinical recurrence Prognostic Clinical recurrence vs. biochemical recurrence <0.0061 Tissue 22589488
2000 Methylation status of ALPL Methylation Humans Differentially Methylated in Clinical recurrence Prognostic Systemic recurrence vs. local recurrence <0.0182 Tissue 22589488
2001 Methylation status of AMPH Methylation Humans Differentially Methylated in Clinical recurrence Prognostic Systemic recurrence vs. local recurrence <0.0021 Tissue 22589488
2002 Methylation status of BCDIN3 Methylation Humans Differentially Methylated in Clinical recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2003 Methylation status of BCL11B Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2004 Methylation status of BRD4 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0038 Tissue 22589488
2005 Methylation status of C18orf34 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2006 Methylation status of DCAMKL1 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2007 Methylation status of FGF5 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2008 Methylation status of FLJ42486 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2009 Methylation status of JAM2 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2010 Methylation status of LHX9 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2011 Methylation status of LOC283537 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2012 Methylation status of LRAT Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0034 Tissue 22589488
2013 Methylation status of PDE4B Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2014 Methylation status of POU3F3 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2015 Methylation status of PTGS2 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0153 Tissue 22589488
2016 Methylation status of RASGRF2 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0002 Tissue 22589488
2017 Methylation status of SLC27A6 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0017 Tissue 22589488
2018 Methylation status of SLC03A1 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2019 Methylation status of SPSB4 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2020 Methylation status of STAT3 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0017 Tissue 22589488
2021 Methylation status of SYN2 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0001 Tissue 22589488
2022 Methylation status of TACR3 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0086 Tissue 22589488
2023 Methylation status of TIRAP Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0003 Tissue 22589488
2024 Methylation status of WNT11 Methylation Humans Methylated in systemic Recurrence Prognostic Systemic recurrence vs. local recurrence <0.0011 Tissue 22589488