| Biomarker ID | 1074 |
| PMID | 23431474 |
| Year | 2013 |
| Biomarker | Methylation Status of APC |
| Biomarker Basis | Methylation Based |
| Biomolecule | Methylation |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Hypermethylated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include: Pathways in cancer, Signal transduction, Irinotecan pathway, Actin cytoskeleton regulation, Apoptosis |
| Experiment | Prostate Cancer Vs Benign Prostatic Hyperplasia |
| Type of Biomarker | Diagnostic |
| Cohort | 27 patients with Prostate Cancer (18 paraffin-embedded blocks of cancer patients who under- went radical prostatectomy and 9 patients who under-went transutheral resection of prostate (TURP) and 24 patients with Benign Prostatic Hyperplasia (BPH) were chosen for the study |
| Senstivity | 55.6% |
| Specificity | 100% |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.001 |
| Method Used | NA |
| Clinical | No |
| Remarks | All Patients were taken from Pakistani Origin |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |