Biomarker ID | 2014 |
PMID | 22589488 |
Year | 2012 |
Biomarker | Methylation status of POU3F3 |
Biomarker Basis | Methylation Based |
Biomolecule | Methylation |
Source | Tissue |
Subjects | Humans |
Regulation | Methylated in systemic Recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Systemic recurrence vs. local recurrence |
Type of Biomarker | Prognostic |
Cohort | Systemic recurrence (n = 36) versus local recurrence (n = 44) |
Senstivity | Training: 91.3 (71.9–98.9); validation: 65.5 (40.7–84.6) |
Specificity | Training: 75.2 (57.8–87.8); validation: 70.7 (45.7–88.1) |
AUC | Training: 0.865; validation: 70 |
Accuracy | NA |
Level Of Significance | <0.0001 |
Method Used | Pyrosequencing |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | POU3F3 |