Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 1992 |
| PMID | 22589488 |
| Year | 2012 |
| Biomarker | Methylation status of TMEM74 |
| Biomarker Basis | Methylation Based |
| Biomolecule | Methylation |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Hypermethlated in Recurrent prostate cancer |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | Recurrent prostate cancer Vs nonrecurrent cancer |
| Type of Biomarker | Prognostic |
| Cohort | Recurrence (n = 123) versus nonrecurrence (n = 75) |
| Senstivity | 66.3 (56.1–75.6) |
| Specificity | 68.3 (55.0–79.7) |
| AUC | 0.664 |
| Accuracy | NA |
| Level Of Significance | <0.0005 |
| Method Used | Pyrosequencing |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | TMEM74 |