| Biomarker ID | 1813 |
| PMID | 30470249 |
| Year | 2018 |
| Biomarker | APC; HOXD3; TGFβ2; GSTP1; KLK10 |
| Biomarker Basis | Methylation Based |
| Biomolecule | Methylation |
| Source | Urine |
| Subjects | Humans |
| Regulation | NA |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include (GSTP1): Pathways include: Biological oxidations, Metapathway biotransformation, Pathways in cancer, T cell receptor regulation of apoptosis, Metabolism Pathways include (APC): Pathways in cancer, Signal transduction, Irinotecan pathway, Actin cytoskeleton regulation, Apoptosis Pathways include (HOXD3): T cell receptor regulation of apoptosis |
| Experiment | Prostate Cancer Vs Benign |
| Type of Biomarker | Diagnostic |
| Cohort | 408 patients were selected for the study. Training Cohort consisted of 123 benign samples, 145 PCa samples. Validation Cohort consisted of 59 benign samples and 81 PCa samples. Training and testing cohort were divided in 1:3 ratio |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | Quantitative MethyLight assay |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |