Biomarker ID | 1972 |
PMID | 22589488 |
Year | 2012 |
Biomarker | Methylation status of CRIP1 |
Biomarker Basis | Methylation Based |
Biomolecule | Methylation |
Source | Tissue |
Subjects | Humans |
Regulation | Hypermethlated in Recurrent prostate cancer |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Recurrent prostate cancer Vs nonrecurrent cancer |
Type of Biomarker | Prognostic |
Cohort | Recurrence (n = 123) versus nonrecurrence (n = 75) |
Senstivity | Training: 61.2 (50.8–70.9); validation: 65.0 (40.7–84.6) |
Specificity | Training: 60.0 (46.5–72.4); validation: 65.6 (40.7–84.6) |
AUC | Training: 0.638; validation: 0.727 |
Accuracy | NA |
Level Of Significance | <0.0037 |
Method Used | Pyrosequencing |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | CRIP1 |