Biomarker ID | 1999 |
PMID | 22589488 |
Year | 2012 |
Biomarker | Methylation status of ZNF135 |
Biomarker Basis | Methylation Based |
Biomolecule | Methylation |
Source | Tissue |
Subjects | Humans |
Regulation | Differentially Methylated in Clinical recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Clinical recurrence vs. biochemical recurrence |
Type of Biomarker | Prognostic |
Cohort | clinical recurrence (n = 80) versus biochemical recurrence (n = 43) |
Senstivity | Training: 59.3 (45.7–71.9); validation: 50.0 (27.2–72.8) |
Specificity | Training: 61.5 (44.6–76.6); validation: 50.0 (27.2–72.8) |
AUC | Training: 0.66; validation: 0.56 |
Accuracy | NA |
Level Of Significance | <0.0061 |
Method Used | Pyrosequencing |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | ZNF135 |