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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1190
PMID23918943
Year2013
BiomarkerMethylation Status of GSTP1
Biomarker BasisMethylation Based
BiomoleculeMethylation
SourceTissue
SubjectsHumans
RegulationHypermethylated in Prostate Cancer
Odds Ratio/Hazard Ratio/Relative RiskCohort 1: univariate : [HR = 1.670 (95% CI: 0.694-4.018), p-value=0.253]
Effect on PathwaysPathways include: Biological oxidations, Metapathway biotransformation, Pathways in cancer, T cell receptor regulation of apoptosis, Metabolism
ExperimentBiochemical recurrence
Type of BiomarkerPrognostic
CohortNonmalignant samples [(adjacent normal [ADJ-N], benign prostatic hyperplasia (BPH)( n = 35)] and radical prostatectomy (RP) samples (n = 293) were chosen for the study
SenstivityNA
SpecificityNA
AUC0.92
AccuracyNA
Level Of SignificanceP < 0.001
Method Usedquantitative methylation specific PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameGSTP1