Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 1988 |
| PMID | 22589488 |
| Year | 2012 |
| Biomarker | Methylation status of SPSB4 |
| Biomarker Basis | Methylation Based |
| Biomolecule | Methylation |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Hypermethlated in Recurrent prostate cancer |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | Recurrent prostate cancer Vs nonrecurrent cancer |
| Type of Biomarker | Prognostic |
| Cohort | Recurrence (n = 123) versus nonrecurrence (n = 75) |
| Senstivity | 62.2 (51.9–71.8) |
| Specificity | 61.7 (48.2–73.9) |
| AUC | 0.658 |
| Accuracy | NA |
| Level Of Significance | <0.0008 |
| Method Used | Pyrosequencing |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | SPSB4 |