Biomarker ID | 1998 |
PMID | 22589488 |
Year | 2012 |
Biomarker | Methylation status of TNFRSF10D |
Biomarker Basis | Methylation Based |
Biomolecule | Methylation |
Source | Tissue |
Subjects | Humans |
Regulation | Differentially Methylated in Clinical recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Clinical recurrence vs. biochemical recurrence |
Type of Biomarker | Prognostic |
Cohort | clinical recurrence (n = 80) versus biochemical recurrence (n = 43) |
Senstivity | Training: 62.7 (49.2–74.9); validation: 60.8 (36.0–80.8) |
Specificity | Training: 66.6 (49.7–80.9); validation: 75.6 (50.9–91.3) |
AUC | Training: 0.7; validation: 0.69 |
Accuracy | NA |
Level Of Significance | <0.0008 |
Method Used | Pyrosequencing |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | TNFRSF10D |