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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID923
PMID22589488
Year2012
BiomarkerMethylation Status Of CHST7; LMX1B; RAFTLIN; RASGRF2; TNFRSF10D; ZNF135
Biomarker BasisMethylation Based
BiomoleculeMethylation
SourceTissue
SubjectsHumans
RegulationMethylated with Clinical Recurrence
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysNA
Experimentclinical recurrence Vs biochemical recurrence
Type of BiomarkerPrognostic
Cohort4 different sub groups of patients with prostate cancer: (i) tumor (n = 158) versus matched normal tissues (n = 34), (ii) recurrence (n = 98) versus nonrecurrence (n = 60); (iii) clinical recurrence (n = 59) versus biochemical recurrence (n = 39); and (iv) systemic recurrence (n = 23) versus local recurrence (n = 36)
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of SignificanceNA
Method UsedMethylation27 microarrays
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameCHST7, LMX1B, RAFTLIN, RASGRF2, TNFRSF10D, ZNF135