Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 2019 |
| PMID | 22589488 |
| Year | 2012 |
| Biomarker | Methylation status of SPSB4 |
| Biomarker Basis | Methylation Based |
| Biomolecule | Methylation |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Methylated in systemic Recurrence |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | Systemic recurrence vs. local recurrence |
| Type of Biomarker | Prognostic |
| Cohort | Systemic recurrence (n = 36) versus local recurrence (n = 44) |
| Senstivity | 82.6 (61.2–95.0) |
| Specificity | 80.6 (63.9–91.8) |
| AUC | 0.824 |
| Accuracy | NA |
| Level Of Significance | <0.0001 |
| Method Used | Pyrosequencing |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | SPSB4 |