Biomarker ID | 485 |
PMID | 20632177 |
Year | 2010 |
Biomarker | Methylation Status of GSTP1 or RASSF1A |
Biomarker Basis | Methylation Based |
Biomolecule | Methylation |
Source | Urine |
Subjects | Humans |
Regulation | HyperMethylated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include (GSTP1): Biological oxidations, Metapathway biotransformation, Pathways in cancer, T cell receptor regulation of apoptosis, Metabolism |
Experiment | Prostate Cancer Vs No Tumor |
Type of Biomarker | Diagnostic |
Cohort | 115 men were chosen for the study out of which 79 had no tumor and 34 had Prostate Cancer. |
Senstivity | 53.3% [27.4–77.7] |
Specificity | 45.9% [29.8–62.49] |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | Methylation-specific PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | GSTP1: RASSF1 |