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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID485
PMID20632177
Year2010
BiomarkerMethylation Status of GSTP1 or RASSF1A
Biomarker BasisMethylation Based
BiomoleculeMethylation
SourceUrine
SubjectsHumans
RegulationHyperMethylated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways include (GSTP1): Biological oxidations, Metapathway biotransformation, Pathways in cancer, T cell receptor regulation of apoptosis, Metabolism
ExperimentProstate Cancer Vs No Tumor
Type of BiomarkerDiagnostic
Cohort115 men were chosen for the study out of which 79 had no tumor and 34 had Prostate Cancer.
Senstivity53.3% [27.4–77.7]
Specificity45.9% [29.8–62.49]
AUCNA
AccuracyNA
Level Of Significancep<0.05
Method UsedMethylation-specific PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameGSTP1: RASSF1