| Biomarker ID | 703 |
| PMID | 21822036 |
| Year | 2011 |
| Biomarker | Methylation Status of RARB |
| Biomarker Basis | Methylation Based |
| Biomolecule | Methylation |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Hypermethylated in Cancer |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:-Non-small cell lung cancer,Vitamin A and carotenoid metabolism,Nuclear receptor transcription pathway,Nuclear receptors,Small cell lung cancer |
| Experiment | Methylation in Patients with PCa |
| Type of Biomarker | Prognostic |
| Cohort | 34 patients with untreated prostate cacner were selected, The cases were diagnosed with early- (pT2, n=21) or medium-stage (pT3, n=13) prostate carcinoma of score 6 (n=24) or 7 (n=10). |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | NA |
| Method Used | Real-time methylation-specific PCR |
| Clinical | No |
| Remarks | The genes were more methylated than that compared to from urine samples. |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | RARB |