Biomarker ID | 1213 |
PMID | 24065480 |
Year | 2013 |
Biomarker | Methylation Status of HIST1H4K |
Biomarker Basis | Methylation Based |
Biomolecule | Methylation |
Source | Urine |
Subjects | Humans |
Regulation | Hypermethylated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: Type II interferon signaling (interferon-gamma), Systemic lupus erythematosus |
Experiment | Prostate Cancer Vs Normal Prostate |
Type of Biomarker | Diagnostic |
Cohort | 57 PC patients, 29 controls with be- nign prostatic hyperplasia (BPH) and 50 young asymptomatic men (YAM) were investigated |
Senstivity | NA |
Specificity | NA |
AUC | 0.763; 95% CI: (0.672-0.839) |
Accuracy | NA |
Level Of Significance | p<0.0001 |
Method Used | RT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |