| Biomarker ID | 1864 |
| PMID | 30373654 |
| Year | 2018 |
| Biomarker | Methlyation Status of APC, GSTP1 RARβ2 |
| Biomarker Basis | Methylation Based |
| Biomolecule | Methylation |
| Source | Urine |
| Subjects | Humans |
| Regulation | Methylated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include (GSTP1): Biological oxidations, Metapathway biotransformation, Pathways in cancer, T cell receptor regulation of apoptosis, Metabolism Pathways include (APC): Pathways in cancer, Signal transduction, Irinotecan pathway, Actin cytoskeleton regulation, Apoptosis |
| Experiment | Prostate Cancer Vs Controls |
| Type of Biomarker | Diagnostic |
| Cohort | 32 normal controls along with 87 Prostate cancer samples were selected for analysis |
| Senstivity | 100% |
| Specificity | 75% |
| AUC | 0.9817 |
| Accuracy | 93.3% |
| Level Of Significance | p<0.05 |
| Method Used | KAPA SYBR FAST qPCR Kit |
| Clinical | No |
| Remarks | All Genes except GSTP1 showed significant methylation, between cancerous and controls |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |