Biomarker ID | 1869 |
PMID | 30373654 |
Year | 2018 |
Biomarker | Methlyation Status of APC |
Biomarker Basis | Methylation Based |
Biomolecule | Methylation |
Source | Tissue |
Subjects | Humans |
Regulation | Methylated in Gleason Grade 2-5 |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: Pathways in cancer, Signal transduction, Irinotecan pathway, Actin cytoskeleton regulation, Apoptosis |
Experiment | Low & Intermediate Risk Vs High Risk |
Type of Biomarker | Prognostic |
Cohort | 15 normal prostate tissues along with 74 Prostate cancer samples were selected for analysis. 33 patients had Low & Intermediate Risk and 41 had High RIsk |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.01 |
Method Used | KAPA SYBR FAST qPCR Kit |
Clinical | No |
Remarks | Risk was catergorized according to CAPRA Score |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |