The total number of records retrieved from this search are 67. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_3738	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	22RV1	NA	NA	NA	NA	NA	Balb/c-rag and gamma negative xenograft for 22Rv1 (2.0E+6)	1.0E+7 pfu	NA	Regression in tumor volume to 0.4 cm after day 80	Intratumoral	NA	NA	NA	29696636
OV_3739	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	22RV1	NA	NA	NA	NA	NA	Balb/c-rag and gamma negative xenograft for 22Rv1 (2.0E+6)	1.0E+7 pfu	NA	Complete regression in tumor after day 80	Intravenous	NA	NA	NA	29696636
OV_3740	Vesicular stomatitis virus	VSV-GP	RNA	Rhabdoviridae	virus expressing GP protein	Yes	No	No	ATCC	Human prostate cancer cell line	VCaP	NA	NA	NA	NA	NA	Balb/c-rag and gamma negative xenograft for VCap (2.0E+6)	1.0E+7 pfu	NA	Regression in tumor volume to 0.3 cm after day 80	Intratumoral	NA	NA	NA	29696636
OV_3771	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3772	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (50mg/kg)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume to below 500mm after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3773	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990/Gemcitabine resistant	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3774	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (50mg/kg)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990/Gemcitabine resistant	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume to below 300mm after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_4083	Adenovirus	Adenovirus ZD55	DNA	Adenoviridae	Virus encoded with drosophila dNK gene	No	Virus in combination with drug DFDC(10mg/kg)	No	Shanghai cell collection	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for MCF7 (1.0E+7)	1.0E+9 pfu	NA	Virus and drug prolongs the mice survival and reduction in tumor volume to 1000mm compared to control 3000mm after 60 days	Intratumoral	Virus induced apoptosis in cancer cell	NA	NA	26203222
OV_4204	Adenovirus	Ad-CXCR4-DAL1	DNA	Adenoviridae	Virus expressing DAL-1 gene under promoter CXXR4	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice subcutaneously xenograft for A549 cell (2.0E+6)	1.0E+9 pfu, every other day for 3 times	NA	Reduction in tumor volume to 1.5 centimeter cube after 28 days compared to control 7 centimeter cube	Intratumoral	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4225	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 21 days in mice 1 and increase in PFS above 200 days compared to control 75 days	Intratumoral	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4226	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 42 days in mice 2 and increase in PFS above 200 days compared to control 75 days	Intratumoral	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4227	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 49 days in mice 3 and increase in PFS above 200 days compared to control 75 days	Intratumoral	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4228	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 56 days in mice 4 and increase in PFS above 200 days compared to control 75 days	Intratumoral	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4229	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)	1.0E+6 pfu	NA	Reduction in tumor volume to 100 cubic millimetet after 70 days in mice 1 and increase in PFS above 200 days from 150 days to control	Intratumoral	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4230	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 49 days in mice 2 and increase in PFS above 200 days from 150 days to control	Intratumoral	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4231	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 49 days in mice 3 and increase in PFS above 200 days from 150 days to control	Intratumoral	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4232	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 56 days in mice 4 and increase in PFS above 200 days from 150 days to control	Intratumoral	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4233	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 56 days in mice 5 and increase in PFS above 200 days from 150 days to control	Intratumoral	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4234	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for IMR-32 (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 70 days in mice 6 and increase in PFS above 200 days from 150 days to control	Intratumoral	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4235	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Reduction in tumor volume to 1000 cubic millimeter in mice 1 after 56 days	Intravenous	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4236	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 28 days in mice 2	Intravenous	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4237	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 28 days in mice 3	Intravenous	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4238	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 28 days in mice 4	Intravenous	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4239	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 48 days in mice 5	Intravenous	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4240	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 56 days in mice 6	Intravenous	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4241	Sindbis virus	AR339	RNA	Togaviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c AnNcrj-nu/nu female mice xenograft for SK-N-SH (1.0E+6)	1.0E+6 pfu	NA	Complete reduction in tumor volume after 56 days in mice 7	Intravenous	Virus induce apoptosis process leads to cancer cell death	Increased expression of Bcl-2 and Bcl-xL expression	NA	26298056
OV_4364	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with 8-CPT-cAMP (20mg/kg/day)	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice subcutaneous xenograft for HCT-116 (5.0E+6)	3.0E+7 pfu	NA	Reduction in tumor volume to below 0.4 cubic centimeter after 22 days compared to control 1.2 cubic centimeter	Intravenous	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4365	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with 8-CPT-cAMP (20mg/kg/day)	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice subcutaneous xenograft for Hep3B (5.0E+6)	5.0E+6 pfu	NA	Reduction in tumor volume to below 1.5 cubic centimeter after 22 days compared to control 7.5 cubic centimeter	Intravenous	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4366	Alphavirus	M1	RNA	Togaviridae	None	No	Virus in combination with 8-CPT-cAMP (20mg/kg/day)	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice subcutaneous xenograft for Capan-1 (1.0E+7)	3.0E+7 pfu	NA	Reduction in tumor volume to below 0.2 cubic centimeter after 22 days compared to control 0.8 cubic centimeter	Intravenous	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4603	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for A549 cell (5.0E+6)	5.0E+8 pfu	NA	Tumor volume reduced to 300 cubic mm comapred to control 700 cubic mm after 40 days	Intratumoral	Virus induced apoptosis	NA	NA	27080225
OV_4604	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for A549 cell (5.0E+6)	5.0E+8 pfu	NA	Tumor volume reduced to 220 cubic mm comapred to control 700 cubic mm after 40 days	Intratumoral	Virus induced apoptosis	NA	NA	27080225
OV_4605	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for A549 cell (5.0E+6)	5.0E+8 pfu	NA	Tumor volume reduced to 200 cubic mm comapred to control 700 cubic mm after 40 days	Intratumoral	Virus induced apoptosis	NA	NA	27080225
OV_4606	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for A549 cell (5.0E+6)	5.0E+8 pfu	NA	Tumor volume reduced to below 100 cubic mm comapred to control 700 cubic mm after 40 days	Intratumoral	Virus induced apoptosis	NA	NA	27080225
OV_5223	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for H1299 (2.0E+6 cells)	1.0E+7 pfu	NA	No significant reduction in tumor volume compared to control	Intratumoral	NA	NA	NA	27760834
OV_5224	Adenovirus	TRAD-shLuc	DNA	Adenoviridae	Virus having shorthairpin RNA for Luciferase gene knockout	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for H1299 (2.0E+6 cells)	1.0E+7 pfu	NA	No significant reduction in tumor volume compared to control	Intratumoral	NA	NA	NA	27760834
OV_5225	Adenovirus	TRAD-shDICER	DNA	Adenoviridae	Virus having shorthairpin RNA for DICER	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for H1299 (2.0E+6 cells)	1.0E+7 pfu	NA	Reduction in tumor volume to 1000 cubic mm after 35 days compared to control 6000 cubic mm	Intratumoral	NA	NA	NA	27760834
OV_5226	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for SKOV3 (2.0E+6 cells)	1.0E+7 pfu	NA	Reduction in tumor volume to 2500 cubic mm after 45 days compared to control 3500 cubic mm	Intratumoral	NA	NA	NA	27760834
OV_5227	Adenovirus	TRAD-shLuc	DNA	Adenoviridae	Virus having shorthairpin RNA for Luciferase gene knockout	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for SKOV3 (2.0E+6 cells)	1.0E+7 pfu	NA	Reduction in tumor volume to 2500 cubic mm after 45 days compared to control 3500 cubic mm	Intratumoral	NA	NA	NA	27760834
OV_5228	Adenovirus	TRAD-shDICER	DNA	Adenoviridae	Virus having shorthairpin RNA for DICER	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for SKOV3 (2.0E+6 cells)	1.0E+7 pfu	NA	Reduction in tumor volume to 800 cubic mm after 45 days compared to control 3500 cubic mm	Intratumoral	NA	NA	NA	27760834
OV_5229	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for 4T1 (1.0E+5 cells)	NA	NA	Reduction in tumor volume 700 cubic mm compared to control 1700 cubic mm after 33 days	Intratumoral	Induction of apoptosis	Increase production of IFN-gama and IL-2	NA	27776794
OV_5230	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for 4T1 (1.0E+5 cells)	NA	NA	Reduction in tumor volume 4200 cubic mm compared to control 1700 cubic mm after 33 days	Intratumoral	Induction of apoptosis	Increase production of IFN-gama and IL-2	NA	27776794
OV_5332	Adenovirus	ZD55-IL18	DNA	Adenoviridae	virus having insertion of IL18 gene	No	Virus in combination with DTIC 100 microgram per ml	Virus expressing IL18 gene	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for A375 (2.0E+6)	10 MOI	NA	Reduction in tumor volume to 250 cubic mm after six week compared to control 800 cubic mm	NA	Virus induced apoptosis as measured by TUNEL assay	NA	NA	27895465
OV_5333	Herpes simplex virus	HSV2	DNA	Herpesviridae	Deletion mutant for ICP34.5 and ICP47 gene and insertion of GMCSF	Yes	No	Virus expressing GMCSF gene	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for CT26 (5.0E+5)	5.0E+6 pfu	NA	Reduction in tumor volume 1200 cubic mm compared to control 2500 cubic mm after 28 days	Intratumoral	Virus induced apoptosis as measured by TUNEL assay	Induce prolifration of tumor specific T cell	NA	28223815
OV_5357	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for 3.0E+5 MIAPaCa2	2.0E+6 pfu	NA	Reduction in tumor volume to 1700 cubic mm after 60 days compared to 2700 cubic mm	Intratumoral	Virus induced apoptosis	NA	NA	28315430
OV_5358	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for 5.0E+5 BxPC3	2.0E+6 pfu	NA	Reduction in tumor volume to 1000 cubic mm after 60 days compared to 2700 cubic mm	Intratumoral	Virus induced apoptosis	NA	NA	28315430
OV_5359	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for 5.0E+5 PANC1	2.0E+6 pfu	NA	Reduction in tumor volume to 400 cubic mm after 60 days compared to 1000 cubic mm	Intratumoral	Virus induced apoptosis	NA	NA	28315430
OV_5360	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	No	Virus in combination with Gemcitabine 1.5mg/kg	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for 3.0E+5 MIAPaCa2	2.0E+6 pfu	NA	Reduction in tumor volume to 500 cubic mm after 60 days compared to 2700 cubic mm	Intratumoral	Virus induced apoptosis	NA	NA	28315430
OV_5361	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	No	Virus in combination with Gemcitabine 1.5mg/kg	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for 5.0E+5 BxPC3	2.0E+6 pfu	NA	Reduction in tumor volume to 400 cubic mm after 60 days compared to 2700 cubic mm	Intratumoral	Virus induced apoptosis	NA	NA	28315430
OV_5362	Adenovirus	YDC002	DNA	Adenoviridae	Virus having insertion mutant for relaxin gene	No	Virus in combination with Gemcitabine 1.5mg/kg	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for 5.0E+5 PANC1	2.0E+6 pfu	NA	Reduction in tumor volume to 100 cubic mm after 60 days compared to 1000 cubic mm	Intratumoral	Virus induced apoptosis	NA	NA	28315430
OV_5368	Herpes simplex virus	HF10	DNA	Herpesviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice isograft for 1.0E+6 MC26 cells	1.0E+7 pfu on day 10, 17 and 24	NA	Reduction in tumor volume to 500 mm compared to control 2500 mm after 28 days and increase in survival time	Subcutaneous	NA	Stimulation of cytotoxic CD8 T cells	NA	28331843
OV_5381	Maraba virus	MG1	RNA	Rhabdoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice isograft for 2.0E+5 4T1 cells	No	NA	Reduction in tumor volume to 400 cubic mm compared to control 800 cubic mm after 25 days and increase in survival time to 45 days compared to 40 days control	Intratumoral	Induction of apoptosis	Level of IFN beta production does not effected by combination	In clinical trial for various cancer cell line	27503504
OV_5382	Maraba virus	MG1	RNA	Rhabdoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice isograft for 2.0E+5 EMT6 cells	No	NA	Reduction in tumor volume to 800 cubic mm compared to control 1000 cubic mm after 18 days and increase in survival time to 30 days compared to 25 days control	Intratumoral	Induction of apoptosis	Level of IFN beta production does not effected by combination	In clinical trial for various cancer cell line	27503504
OV_5384	Maraba virus	MG1	RNA	Rhabdoviridae	None	No	Virus in combination with 2mg/kg micromolar palcitaxel for 48 hours	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice isograft for 2.0E+5 4T1 cells	No	NA	Reduction in tumor volume to 200 cubic mm compared to control 800 cubic mm after 25 days and increase in survival time to 60 days compared to 40 days control	Intratumoral	Induction of apoptosis	Level of IFN beta production does not effected by combination	In clinical trial for various cancer cell line	27503504
OV_5385	Maraba virus	MG1	RNA	Rhabdoviridae	None	No	Virus in combination with 10mg/kg micromolar palcitaxel for 48 hours	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice isograft for 2.0E+5 EMT6 cells	No	NA	Reduction in tumor volume to 400 cubic mm compared to control 1000 cubic mm after 18 days and increase in survival time to 30 days compared to 25 days control	Intratumoral	Induction of apoptosis	Level of IFN beta production does not effected by combination	In clinical trial for various cancer cell line	27503504
OV_5457	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Balb/c mice injected with tumor	1.0E+4 pfu	NA	Mice failed to develop cancer	Subcutaneous	NA	NA	NA	US41098983
OV_5458	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Balb/c mice injected with tumor	1.0E+5 pfu	NA	Mice failed to develop cancer	Subcutaneous	NA	NA	NA	US41098983
OV_5459	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Balb/c mice injected with tumor	1.0E+6 pfu	NA	Mice failed to develop cancer	Subcutaneous	NA	NA	NA	US41098983
OV_5484	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 2%	Intraneoplastic	NA	NA	NA	US5585096
OV_5485	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 5%	Intraneoplastic	NA	NA	NA	US5585096
OV_5510	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 2%	Intraneoplastic	NA	NA	NA	US5728379
OV_5511	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 5%	Intraneoplastic	NA	NA	NA	US5728379
OV_5536	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 2%	Intraneoplastic	NA	NA	NA	US6139834
OV_5537	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 5%	Intraneoplastic	NA	NA	NA	US6139834
OV_5673	Adenovirus	OV802	DNA	Adenoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Balb/c mice xenograft for A549 (5.0E+6 )	4.0E+8 pfu	NA	Reduction in tumor volume to below 300 after 80 days	NA	NA	Induction of IFN-Gamma, IL6 and other immunostimulatory cytokines production	NA	US7473418
OV_5883	Parovirus	Mutant	DNA	Paroviridae	Deletion mutatnt for Gamma 34.5, ICP6 and ICP47 gene	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Balb/c mice xenograft for PANC-1	1 RU per ml	NA	Tumor volume reduced to 500mm after 83 days	Intratumoral	NA	NA	NA	US8916176
OV_5884	Parovirus	Mutant	DNA	Paroviridae	Deletion mutatnt for Gamma 34.5, ICP6 and ICP47 gene	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Balb/c mice xenograft for HeLa (2.0E+6)	1 RU per ml	NA	Survival time increased up to 40 days	Intratumoral	NA	NA	NA	US8916176
OV_5914	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for B16-F10 (1.0E+5)	5.0E+6 pfu	NA	Complete regression in tumor volume after 25 days	Intratumoral	NA	Virus induced IFN-gamma production	NA	US10035984