Detailed description page of Selected OV_ID


OV_5223 details
Primary information
OV_IDOV_5223
Virus Name Adenovirus
Strainwild type
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice xenograft for H1299 (2 × 10⁶ cells)
In-vivo virus concentration1 × 10⁷ pfu
In-vivo toxicityNA
In-vivo resultNo significant reduction in tumor volume compared to control
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID27760834