Detailed description page of Selected OV_ID


OV_5884 details
Primary information
OV_IDOV_5884
Virus Name Parovirus
StrainMutant
Virus typeDNA
Virus familyParoviridae
Modification in virus genomeDeletion mutatnt for Gamma 34.5, ICP6 and ICP47 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeYes
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBalb/c mice xenograft for HeLa (2 ×10⁶)
In-vivo virus concentration1 RU/ml
In-vivo toxicityNA
In-vivo resultSurvival time increased up to 40 days
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMIDUS8916176