Detailed description page of Selected OV_ID


OV_5914 details
Primary information
OV_IDOV_5914
Virus Name Newcastle disease virus
StrainNDV-F3aa
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeVirus expressing NS1 protein
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c mice xenograft for B16-F10 (1.0 ×10⁵)
In-vivo virus concentration5 ×10⁶ pfu
In-vivo toxicityNA
In-vivo resultComplete regression in tumor volume after 25 days
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectVirus induced IFN-gamma production
Clinical trialNA
PMIDUS10035984