Detailed description page of Selected OV_ID


OV_3740 details
Primary information
OV_IDOV_3740
Virus Name Vesicular stomatitis virus
StrainVSV-GP
Virus typeRNA
Virus familyRhabdoviridae
Modification in virus genomevirus expressing GP protein
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman prostate cancer cell line
Cell lineVCaP
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBalb/c-rag and gamma negative xenograft for VCap (2 × 10⁶)
In-vivo virus concentration1 × 10⁷ pfu
In-vivo toxicityNA
In-vivo resultRegression in tumor volume to 0.3 cm after day 80
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID29696636