Detailed description page of Selected OV_ID


OV_5673 details
Primary information
OV_IDOV_5673
Virus Name Adenovirus
StrainOV802
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBalb/c mice xenograft for A549 (5 ×10⁶ )
In-vivo virus concentration4 ×10⁸ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor volume to below 300 after 80 days
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectInduction of IFN-Gamma, IL6 and other immunostimulatory cytokines production
Clinical trialNA
PMIDUS7473418