Detailed description page of Selected OV_ID


OV_5537 details
Primary information
OV_IDOV_5537
Virus Name Herpes simplex virus
StrainG207-2
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDeletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman glioma cell line
Cell lineU-87 MG
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBalb/c mice xenograft for U-87MG
In-vivo virus concentration5 ×10⁷
In-vivo toxicityNA
In-vivo resultReduction in tumor growth below 5%
Mode of deliveryIntraneoplastic
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMIDUS6139834