Detailed description page of Selected OV_ID


OV_5358 details
Primary information
OV_IDOV_5358
Virus Name Adenovirus
StrainYDC002
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeVirus having insertion mutant for relaxin gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice xenograft for 5 × 10⁵ BxPC3
In-vivo virus concentration2 × 10⁶ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor volume to 1000 cubic mm after 60 days compared to 2700 cubic mm
Mode of deliveryIntratumoral
Pathway inductionVirus induced apoptosis
Immunogenic effectNA
Clinical trialNA
PMID28315430