| Primary information |
|---|
| OV_ID | OV_3739 |
| Virus Name | Vesicular stomatitis virus |
| Strain | VSV-GP |
| Virus type | RNA |
| Virus family | Rhabdoviridae |
| Modification in virus genome | virus expressing GP protein |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Human prostate cancer cell line |
| Cell line | 22RV1 |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | Balb/c-rag and gamma negative xenograft for 22Rv1 (2 × 10â¶) |
| In-vivo virus concentration | 1 × 10ⷠpfu
|
| In-vivo toxicity | NA |
| In-vivo result | Complete regression in tumor after day 80 |
| Mode of delivery | Intravenous |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 29696636 |