Detailed description page of Selected OV_ID


OV_5230 details
Primary information
OV_IDOV_5230
Virus Name Parovirus
Strainwild type
Virus typeDNA
Virus familyParoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice xenograft for 4T1 (1 × 10⁵cells)
In-vivo virus concentrationNA
In-vivo toxicityNA
In-vivo resultReduction in tumor volume 4200 cubic mm compared to control 1700 cubic mm after 33 days
Mode of deliveryIntratumoral
Pathway inductionInduction of apoptosis
Immunogenic effectIncrease production of IFN-gama and IL-2
Clinical trialNA
PMID27776794