A database of FDA approved therapeutic peptides and proteins
| ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1022 | Th1003 | Dornase alfa | LKIAAFNIQTFGETKMSNAT Full view | 255 | Ib | Metabolic | Pulmozyme | Genentech Inc | N.A. | Administered by inhalation of an aerosol mist produced by a compressed air driven nebulizer system | Enzymes | DNA |
| 1023 | Th1003 | Dornase alfa | LKIAAFNIQTFGETKMSNAT Full view | 255 | Ib | Metabolic | Viscozyme | Roche (Chile) | N.A. | Administered by inhalation of an aerosol mist produced by a compressed air driven nebulizer system | Enzymes | DNA |
| 1049 | Th1008 | Peginterferon alfa-2a | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Pegasys | Hoffman-La Roche Inc | Sterile, preservative-free, colorless to light yellow injectable solution | Subcutaneous Injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1055 | Th1009 | Alteplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ib | Hematological,Metabolic | Activase | Genentech Inc | Sterile, white to off-white, lyophilized powder | Intravenous | Thrombolytic Agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
| 1059 | Th1010 | Interferon alfa-n1 | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Infectious /Immunological | Wellferon | GlaxoSmithKline | Solution | Injection | Antiviral Agents, Immunologic factors, Immunosuppressiv agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1064 | Th1011 | Darbepoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Aranesp | Amgen Inc | Sterile, colorless, preservative-free solution containing polysorbate | Intravenousor Subcutaneous administration | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
| 1067 | Th1012 | Reteplase | SYQGNSDCYFGNGSAYRGTH Full view | 255 | Ib | Hematological,Metabolic | Retavase | Centocor | Sterile, white, lyophilized powder | Intravenous Injection | Fibrinolytic Agents, Thrombolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1 |
| 1071 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Binocrit | Sandoz | Clear colourless solution | Subcutaneous and Intravenous infusion | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
| 1072 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epocept | Lupin pharma | N.A. | Injection | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
| 1073 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epofit | Intas pharma | N.A. | N.A. | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
| 1074 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epogen | Amgen Inc. | Sterile, colorless liquid | Subcutaneous Injection | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
| 1075 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epogin | Chugai | N.A. | Subcutaneous or by Intravenous. | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
| 1076 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Eprex | Janssen-Cilag. Ortho Biologics LLC | Solution | Subcutaneous and Intravenous infusion | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
| 1077 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Nanokine | Nanogen Pharmaceutical biotechnology, Vietnam) | Sterile, white, lyophilized powder. The reconstituted preparation with 1 ml solvent (containing 0.9% benzyl alcohol) results in a clear, colorless solution. | Injection | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
| 1078 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Procrit | Ortho Biotech | Sterile, colorless liquid in an isotonic sodium chloride/sodium citrate buffered solution or a sodium chloride/sodium phosphate buffered solution | Intravenous(IV) or Subcutaneous (SC) administration. | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
| 1098 | Th1014 | Salmon Calcitonin | CSNLSTCVLGKLSQELHKLQ Full view | 32 | Ib | Osteological | Calcimar | N.A. | Solution | Subcutaneous or Intramuscular Injection | Bone Density Conservation Agents, Antihypercalcemic agents, Anti-osteoporotic agents | Calcitonin receptor |
| 1099 | Th1014 | Salmon Calcitonin | CSNLSTCVLGKLSQELHKLQ Full view | 32 | Ib | Osteological | Fortical | N.A. | Nasal spray | Intranasal use | Bone Density Conservation Agents, Antihypercalcemic agents, Anti-osteoporotic agents | Calcitonin receptor |
| 1100 | Th1014 | Salmon Calcitonin | CSNLSTCVLGKLSQELHKLQ Full view | 32 | Ib | Osteological | Miacalcin | Novartis | Solution | Subcutaneous or Intramuscular Injection | Bone Density Conservation Agents, Antihypercalcemic agents, Anti-osteoporotic agents | Calcitonin receptor |
| 1110 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon | Interferon Sciences Inc. | Solution | Injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1111 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon LDO | N.A. | N.A. | N.A. | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1112 | Th1015 | Interferon alfa-n3 | Alpha-2A:CDLPQTHSLG< Full view | 235 | Ib | Immunological | Alferon N Injection | N.A. | N.A. | N.A. | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1117 | Th1016 | Pegfilgrastim | MTPLGPASSLPQSFLLKCLE Full view | 175 | Ib | Immunological | Neulasta | Amgen Inc. | Solution | Subcutaneous injection | Immunosuppressive Agents, Anti-neutropenic agents | Granulocyte colony-stimulating factor receptor,Neutrophil elastase |
| 1120 | Th1017 | Sargramostim | APARSPSPSTQPWEHVNAIQ Full view | 127 | Ib | Immunological | Leucomax | Novartis | Solution | Subcutaneous and Intravenous infusion | Immunosuppressive Agents | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan |
| 1121 | Th1017 | Sargramostim | APARSPSPSTQPWEHVNAIQ Full view | 127 | Ib | Immunological | Leukine | Berlex Laboratories Inc | Sterile, preserved (1.1% benzyl alcohol), injectable solution (500 mcg/mL) and also as sterile, white, preservative free lyophilized powder (250 mcg) that requires reconstitution with 1 mL sterile water for Injection | Subcutaneous Injection (SC) or Intravenous infusion (IV) | Immunosuppressive Agents | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan |
| 1135 | Th1019 | Peginterferon alfa-2b | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | PEG-Intron | Schering Corp | Powder | Subcutaneous injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1136 | Th1019 | Peginterferon alfa-2b | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Unitron PEG | N.A. | Lyophilized powder | Subcutaneous injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1210 | Th1028 | Tenecteplase | SYQVICRDEKTQMIYQQHQS Full view | 255 | Ib | Hematological,Metabolic | TNKase | Genentech Inc | Sterile, white to off-white, lyophilized powder | Intravenous Injection | Thrombolytic Agents, Fibrinolytic agents | Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1,Plasminogen activator inhibitor 2,Tetranectin,Keratin, type II cytoskeletal 8,Annexin A2,Calreticulin,Calnexin,Prolow-density lipoprotein |
| 1215 | Th1029 | Menotropins | Alpha-Chain(LH):APD< Full view | 222 | Ib | Hormonal disorders | Menopur | N.A. | Sterile, lyophilized powder which is reconstitution with sterile 0.9% Sodium Chloride Injection. | Subcutaneous Injection | Fertility Agents | Follicle-stimulating hormone receptor,Lutropin-choriogonadotropic hormone receptor |
| 1216 | Th1029 | Menotropins | Alpha-Chain(LH):APD< Full view | 222 | Ib | Hormonal disorders | Repronex | N.A. | Sterile, lyophilized form | Subcutaneous or Intramuscular Injection. | Fertility Agents | Follicle-stimulating hormone receptor,Lutropin-choriogonadotropic hormone receptor |
| 1226 | Th1030 | Interferon gamma-1b | CYCQDPYVKEAENLKKYFNA Full view | 146 | Ib | Immunological | Actimmune | InterMune Inc | Sterile, clear, colorless solution | Subcutaneous Injection | Immunosuppressive Agents | Interferon gamma receptor 1,Interferon gamma receptor 2 |
| 1229 | Th1031 | Interferon Alfa-2a, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Roferon A | Hoffmann-La Roche Inc | Solution | Subcutaneous Injection | N.A. | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1230 | Th1031 | Interferon Alfa-2a, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Veldona | Amarillo Biosciences | N.A. | N.A. | N.A. | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1234 | Th1032 | Coagulation factor VIIa | ANAFLEELRPGSLERECKEE Full view | 255 | Ib | Hematological,Metabolic | NovoSeven | Novo Nordisk | Sterile, white lyophilized powder | Injection | Thrombotic Agents, Coagulants | Coagulation factor X,Serine protease hepsin,Tissue factor pathway inhibitor,Vitamin K-dependent gamma-carboxylase,Coagulation factor VII,Tissue factor |
| 1242 | Th1033 | Oprelvekin | GPPPGPPRVSPDPRAELDST Full view | 177 | Ib | Cancer/Haemetological | Neumega | Genetics Institute Inc | Sterile, lyophilized powder | Subcutaneous injection | Coagulants and Thrombotic Agents, Anti-neoplastic agents | Interleukin-11 receptor subunit alpha |
| 1246 | Th1034 | Palifermin | SYDYMEGGDIRVRRLFCRTQ Full view | 140 | Ib | Cancer | Kepivance | Amgen Inc | Sterile, lyophilized powder | Intravenous infusion | Anti-Mucositis Agents | Fibroblast growth factor receptor 2,Neuropilin-1,Fibroblast growth factor receptor 1,Fibroblast growth factor receptor 4,Fibroblast growth factor receptor 3,Basement membrane-specific heparan sulfate proteoglycan core protein |
| 1257 | Th1036 | Aldesleukin | MAPTSSSTKKTQLQLEHLLL Full view | 134 | Ib | Cancer/Infectious | Proleukin | Chiron Corp | Sterile, white to off-white, lyophilized cake | Intravenous administration | Antineoplastic Agents, Anti-HIV agents | Interleukin-2 receptor subunit beta,Interleukin-2 receptor subunit alpha,Cytokine receptor common subunit gamma |
| 1269 | Th1039 | Lutropin alfa | Alpha Chain: APDVQDC Full view | 213 | Ib | Hormonal | Luveris | Serono | White lyophilised pellet withg clear colourless solvent to make solution | Subcutaneous (SC) administration | Fertility Agents | Lutropin-choriogonadotropic hormone receptor |
| 1341 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Avonex | Biogen Inc | Lyophilized powder vial, Sterile liquid as single used prefilled syringe and also available as single use prefilled autoinjector. | Intramuscular Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1342 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Betaferon | Bayer | Powder and solvent that are made upto make solution. | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1343 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Betaseron | Merck | Sterile, white to off-white powder | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1344 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Blastoferon | Sidus | N.A. | N.A. | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1345 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Extavia | Novartis | Sterile, white to off-white powder | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1346 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Rebif | Merck | Sterile solution in a prefilled syringe or REBIF Rebidose autoinjector | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
| 1363 | Th1052 | Eptifibatide | Mpr-Har-Gly-Asp-Trp- Full view | 7 | Ib | Hematological/Metabolic | INTEGRILIN | Schering-Plough/Essex | Clear, colorless, sterile, non-pyrogenic solution of Eptifibatide | Injection Solution for IIntravenousUse | Platelet Aggregation Inhibitors | Lutropin-choriogonadotropic hormone receptor,Follicle-stimulating hormone receptor |
| 1372 | Th1055 | Follitropin beta | A Chain: APDVQDCPECT Full view | 204 | Ib | Hormonal disorders | Follistim AQ | Merck | Sterile aqueous solution | Subcutaneous or Intramuscular administration | Fertility Agents | Follicle-stimulating hormone receptor |
| 1375 | Th1056 | Vasopressin | CYFQNCPRG Full view | 9 | Ib | Hormonal | Pitressin | JHP Pharmaceuticals | Sterile, aqueous solution of synthetic vasopressin | Intramuscular or Subcutaneous use | Antidiuretic Agents | Vasopressin V2 receptor,Vasopressin V1a receptor,Vasopressin V1b receptor |
| 1376 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Betaseron | Bayer | Sterile, white to off-white powder | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
| 1377 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Betaferon | Bayer | Powder and solvent that are made upto make solution. | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
| 1378 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Extavia | Novartis | Sterile, white to off-white powder | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
| 1379 | Th1058 | Interferon alfacon-1 | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological/Infectious | INFERGEN | Kadmon Pharmaceuticals, LLC. | Sterile, clear, colorless, preservative-free liquid | Subcutaneous Injection | Antiviral Agents and Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |