The total number of records retrieved from this search are 266. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_19	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	1 MOI	70% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_20	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	5 MOI	58% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_21	Adenovirus	oAd/DCN/LRP	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	10 MOI	38% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	IL-6 production increased by 3 folds as compared to normal	NA	26471393
OV_22	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	1 MOI	100% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_23	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	5 MOI	95% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_24	Adenovirus	oAd/DCN/LRP-PEG	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	10 MOI	94% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_25	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	1 MOI	77% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_26	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	5 MOI	72% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_27	Adenovirus	oAd/DCN/LRP-PEG-NT	DNA	Adenoviridae	Insertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol	Yes	No	No	ATCC	Human lung cancer cell line	A549	Grown to 70% confluence	NA	MTT assay	10 MOI	58% cancer cell viability	No	No	NA	No response	NA	Inhibits Wnt/β-catenin and TGF-β1 signaling pathways	NA	NA	26471393
OV_40	Adenovirus	AdCMV/GFP	DNA	Adenoviridae	Mutant with E1 deletion carrying a green fluorescent protein (GFP)	Yes	No	No	ATCC	Human lung cancer cell line	A549	Desnity of 1000000 in 60mm dish	Highly toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	3.5 MOI	13% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_41	Adenovirus	Ad dl1520	DNA	Adenoviridae	E1b mutant with 827-bp deletion and a point mutation with premature stop codon in the E1B55K coding region	Yes	No	No	ATCC	Human lung cancer cell line	A549	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	3.5 MOI	54% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_42	Adenovirus	Ad-cycE	DNA	Adenoviridae	E1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassette	Yes	No	No	ATCC	Human lung cancer cell line	A549	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	3.5 MOI	18% cancer cell viability	No	No	NA	No response	NA	NA	Activates CDK2 and targets the transcriptional repressor pRb	NA	26475304
OV_47	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	Yes	No	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	57% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_48	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with etoposide (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.67 CDI	MTT assay	0.1 MOI	24% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_49	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with epirubicin (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.46 CDI	MTT assay	0.1 MOI	16% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_50	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with doxorubicin (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.88 CDI	MTT assay	0.1 MOI	26% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_51	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with vincristine (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.79 CDI	MTT assay	0.1 MOI	25% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_52	Adenovirus	Ad5WS1	DNA	Adenoviridae	E1B55K-deleted mutant driven by the E1 promoter	No	Viral strain in combination with colchcine (0.02 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.81 CDI	MTT assay	0.1 MOI	28% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_53	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	Yes	No	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	18% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_54	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with etoposide (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.27 CDI	MTT assay	0.1 MOI	4% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_55	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with epirubicin (0.5 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.31 CDI	MTT assay	0.1 MOI	4% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_56	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with doxorubicin (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.33 CDI	MTT assay	0.1 MOI	6% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_57	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with vincristine (0.1 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.89 CDI	MTT assay	0.1 MOI	12% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_58	Adenovirus	Ad5GS3	DNA	Adenoviridae	E1B55K-deleted mutant driven by the MDR1 promoter	No	Viral strain in combination with colchcine (0.02 μg/ml)	No	NA	Human lung cancer cell line	A549	1.0E+6 cells per well	0.78 CDI	MTT assay	0.1 MOI	10% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26515462
OV_314	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	0.5 MOI	28% cancer cell viability at 96 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_315	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	0.5 MOI	78% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_316	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	0.5 MOI	24% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_317	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	1 MOI	24% cancer cell viability at 96 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_318	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	1 MOI	57% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_319	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	1 MOI	18% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_320	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	2 MOI	22% cancer cell viability at 96 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_321	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	2 MOI	45% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_322	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	2 MOI	11% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_326	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	Crystal violet staining	1 MOI	1% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_330	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	Crystal violet staining	2.5 MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_334	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	Crystal violet staining	5 MOI	92% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_338	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	Crystal violet staining	10 MOI	92% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_342	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	Crystal violet staining	20 MOI	100% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_345	Adenovirus	AdLacZ	DNA	Adenoviridae	E1/E3-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	MTT assay	10 MOI	58% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_348	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	No	Virus in combination with temozolomide (TMZ) - 0.6 mM	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	MTT assay	2.5 MOI	18% cancer cell viability	No	No	NA	No response	NA	JNK activation induces autophagy	NA	NA	26561948
OV_351	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	MTT assay	10 MOI	49% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_352	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	MTT assay	10 MOI	26% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_353	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	No	Virus in combination with temozolomide (TMZ) and 3-MA at -0.75 mM and 10 mM concentration, respectively	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	MTT assay	10 MOI	62% cancer cell viability	No	No	NA	No response	NA	JNK activation induces autophagy (Autophagy effect slightly inhibited by 3-MA)	NA	NA	26561948
OV_354	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	No	Virus in combination with temozolomide (TMZ) and 3-MA at -0.75 mM and 10 mM concentration, respectively	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	MTT assay	10 MOI	44% cancer cell viability	No	No	NA	No response	NA	JNK activation induces autophagy (Autophagy effect slightly inhibited by 3-MA)	NA	NA	26561948
OV_355	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	No	Virus in combination with temozolomide (TMZ) and BAF-A1 at -0.75 mM and 10 nM concentration, respectively	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	MTT assay	10 MOI	65% cancer cell viability	No	No	NA	No response	NA	JNK activation induces autophagy (Autophagy effect slightly inhibited by Baf-A1)	NA	NA	26561948
OV_356	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	No	Virus in combination with temozolomide (TMZ) and BAF-A1 at -0.75 mM and 10 nM concentration, respectively	No	ATCC	Human lung cancer cell line	A549	2.5E+4 cells per well	NA	MTT assay	10 MOI	47% cancer cell viability	No	No	NA	No response	NA	JNK activation induces autophagy (Autophagy effect slightly inhibited by Baf-A1)	NA	NA	26561948
OV_1444	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	A549	NA	NA	XTT assay	Log10 pfu/cell	Less than 10% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_2077	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2078	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	1 MOI	All cells was dead	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2079	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	10 MOI	All cells was dead	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2080	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	100 MOI	All cells was dead	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2106	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2107	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2108	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2109	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	100 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2126	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2127	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2128	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2129	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	100 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2211	Newcastle disease virus	wild type	RNA	Paramyxoviridae	None	No	Virus in combination with cisplatin	No	Chinese academy of sciece	Human small cell lung cancer cell line	A549	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for A549 cell line	1.0E+7 pfu	NA	Tumor volume decreased to 500mm after 57 days	Intratumoral	Induction of caspase and apoptotic pathway as detected by Hoechst staining and TUNEL assay	NA	NA	22095029
OV_2780	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	Crystal violet staining	0.1 MOI	No cell death	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2781	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	Crystal violet staining	0.5 MOI	No cell death	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2782	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	Crystal violet staining	1 MOI	No cell death	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2783	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	Crystal violet staining	5 MOI	Moderate cell death	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2784	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	Crystal violet staining	10 MOI	All cell was dead	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2795	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	0.5 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2796	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	1 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2797	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	2 MOI	80% cells are viable	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2798	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	5 MOI	70% cells are viable	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2799	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	10 MOI	50% cells are viable	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2805	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for A549	5.0E+8 pfu	NA	Significant reduction in tumor volume and increased in survival rate fro 15% to 87% at day 60	Intratumoral	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2844	Measles virus	Attenuated strain	RNA	Paramyxoviridae	None	Yes	No	No	Laboratory grown own culture	Human lung cancer cell line	A549	1 million cells per well	NA	Cell death detection kit	1 MOI	28% cells survived	No	No	NA	No response	NA	Activation of caspase-3	NA	NA	23586034
OV_2852	Measles virus	Attenuated strain	RNA	Paramyxoviridae	None	Yes	No	No	Laboratory grown own culture	Human lung cancer cell line	A549	NA	NA	NA	NA	NA	RJ:NMRI nude mice xenograft for A549 cell line (1.5E+7)	1.0E+6 pfu	NA	Significant reduction in tumor volume after 42 days	Intratumoral	Activation of caspase-3	NA	NA	23586034
OV_2934	Newcastle disease virus	wild type	RNA	Paramyxoviridae	Expressing rl gene	Yes	No	No	Peking university china	Human lung cancer cell line	A549	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for A549 cell line (6.3E+8)	6.3E+8 pfu	NA	Tumor volume regressed to 274 +/- 114.20 compared to control 271.78 +/- 110.79 after day 1	Intratumoral	Induction of apoptosis by virus	NA	NA	25364430
OV_2935	Newcastle disease virus	wild type	RNA	Paramyxoviridae	Expressing rl gene	Yes	No	No	Peking university china	Human lung cancer cell line	A549	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for A549 cell line (6.3E+8)	6.3E+8 pfu	NA	Tumor volume regressed to 444.18 +/- 111.22 compared to control 591.45 +/- 244.50 after day 7	Intratumoral	Induction of apoptosis by virus	NA	NA	25364430
OV_2936	Newcastle disease virus	wild type	RNA	Paramyxoviridae	Expressing rl gene	Yes	No	No	Peking university china	Human lung cancer cell line	A549	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for A549 cell line (6.3E+8)	6.3E+8 pfu	NA	Tumor volume regressed to 657.56 +/- 176.74 compared to control 1483.21 +/- 446.75 after 14 day	Intratumoral	Induction of apoptosis by virus	NA	NA	25364430
OV_2937	Newcastle disease virus	wild type	RNA	Paramyxoviridae	Expressing rl gene	Yes	No	No	Peking university china	Human lung cancer cell line	A549	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for A549 cell line (6.3E+8)	6.3E+8 pfu	NA	Tumor volume regressed to 804.96 +/- 176.74 compared to control 1127.88 +/- 274.09 after 21 days	Intratumoral	Induction of apoptosis by virus	NA	NA	25364430
OV_3051	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human lung cancer cell line	A549	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	18% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3052	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human lung cancer cell line	A549	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	10% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3053	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human lung cancer cell line	A549	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	1% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3081	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human lung cancer cell line	A549	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	30% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3082	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human lung cancer cell line	A549	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	15% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3083	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human lung cancer cell line	A549	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	5% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3464	Adenovirus	Adenovirus CRAds	DNA	Adenoviridae	None	Yes	No	No	Cell collection centre china	Human lung cancer cell line	A549	1.0E+5 cells per well	NA	MTS assay	100 MOI	22% inhibition in tumor inhibition	No	No	NA	No response	NA	NA	NA	NA	28638457
OV_3465	Adenovirus	Adenovirus CRAds	DNA	Adenoviridae	None	Yes	No	No	Cell collection centre china	Human lung cancer cell line	A549-DDPR cisplatin resistant	1.0E+5 cells per well	NA	MTS assay	100 MOI	55% inhibition in tumor inhibition	No	No	NA	No response	NA	NA	NA	NA	28638457
OV_3498	Adenovirus	Adenovirus CRAds	DNA	Adenoviridae	None	Yes	No	No	Cell collection centre china	Human lung cancer cell line	A549	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW-620 cell line (1.0E+6)	8.0E+6 pfu	NA	Tumor size regressed to 700mm compared to control 900mm after 65 days	Intratumoral	NA	NA	NA	28638457
OV_3499	Adenovirus	Adenovirus CRAds	DNA	Adenoviridae	None	No	Virus in combination with cisplatin	No	Cell collection centre china	Human lung cancer cell line	A549	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW-620 cell line (1.0E+6)	8.0E+6 pfu	NA	Tumor size regressed to 100mm compared to control 900mm after 65 days	Intratumoral	NA	NA	NA	28638457
OV_3500	Adenovirus	Adenovirus CRAds	DNA	Adenoviridae	None	Yes	No	No	Cell collection centre china	Human lung cancer cell line	A549-DDPR cisplatin resistant	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW-620 cell line (1.0E+6)	8.0E+6 pfu	NA	Tumor size regressed to 800mm compared to control 900mm after 65 days	Intratumoral	NA	NA	NA	28638457
OV_3501	Adenovirus	Adenovirus CRAds	DNA	Adenoviridae	None	No	Virus in combination with cisplatin	No	Cell collection centre china	Human lung cancer cell line	A549-DDPR cisplatin resistant	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW-620 cell line (1.0E+6)	8.0E+6 pfu	NA	Tumor size regressed to 300mm compared to control 900mm after 65 days	Intratumoral	NA	NA	NA	28638457
OV_3711	Enterovirus	ECHO-7 virus stain Rigvir	RNA	Picornaviridae	None	Yes	No	No	Public health england	Human lung cancer cell line	A549	NA	NA	Live cell imaging system	1% virus concentration	92% cell viability	No	No	NA	No response	NA	NA	NA	NA	29581783
OV_3718	Enterovirus	ECHO-7 virus stain Rigvir	RNA	Picornaviridae	None	Yes	No	No	Public health england	Human lung cancer cell line	A549	NA	NA	Live cell imaging system	10% virus concentration	91% cell viability	No	No	NA	No response	NA	NA	NA	NA	29581783
OV_3831	Newcastle disease virus	NDVstrain 852	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	23% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3832	Newcastle disease virus	NDVstrain 320	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	34% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3833	Newcastle disease virus	NDVstrain 264	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	35% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3834	Newcastle disease virus	NDVstrain 776	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	38% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3835	Newcastle disease virus	NDVstrain 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	39% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3836	Newcastle disease virus	NDVstrain 14	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	40% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3837	Newcastle disease virus	NDVstrain 860	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	40% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3838	Newcastle disease virus	NDVstrain 753	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	40% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3839	Newcastle disease virus	NDVstrain AD	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	42% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3840	Newcastle disease virus	NDVstrain 321	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	42% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3841	Newcastle disease virus	NDVstrain 718	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	50% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3842	Newcastle disease virus	NDVstrain 922	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	50% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3843	Newcastle disease virus	NDVstrain 373	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	58% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3844	Newcastle disease virus	NDVstrain 53	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	60% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3845	Newcastle disease virus	NDVstrain 777	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	60% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3846	Newcastle disease virus	NDVstrain 27	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	61% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3847	Newcastle disease virus	NDVstrain 769	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	61% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3848	Newcastle disease virus	NDVstrain 12	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	70% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3849	Newcastle disease virus	NDVstrain 945	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	78% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3850	Newcastle disease virus	NDVstrain 49	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	80% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3851	Newcastle disease virus	NDVstrain 52	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	81% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3852	Newcastle disease virus	NDVstrain 746	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	90% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3853	Newcastle disease virus	NDVstrain 465	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	90% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3854	Newcastle disease virus	NDVstrain 429	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	90% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3855	Newcastle disease virus	NDVstrain 329	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	97% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3856	Newcastle disease virus	NDVstrain 339	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	98% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3857	Newcastle disease virus	NDVstrain 389	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	98% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3858	Newcastle disease virus	NDVstrain 48	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	100% cell viability after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3941	Newcastle disease virus	NDVstrain 264	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	49% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3942	Newcastle disease virus	NDVstrain 264	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	36% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3943	Newcastle disease virus	NDVstrain 264	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	34% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3944	Newcastle disease virus	NDVstrain 320	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	30% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3945	Newcastle disease virus	NDVstrain 320	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	33% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3946	Newcastle disease virus	NDVstrain 320	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	34% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3947	Newcastle disease virus	NDVstrain 321	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	51% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3948	Newcastle disease virus	NDVstrain 321	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	47% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3949	Newcastle disease virus	NDVstrain 321	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	46% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3950	Newcastle disease virus	NDVstrain 373	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	58% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3951	Newcastle disease virus	NDVstrain 373	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	59% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3952	Newcastle disease virus	NDVstrain 373	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	57% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3953	Newcastle disease virus	NDVstrain 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	34% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3954	Newcastle disease virus	NDVstrain 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	45% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3955	Newcastle disease virus	NDVstrain 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	40% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3956	Newcastle disease virus	NDVstrain 852	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	44% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3957	Newcastle disease virus	NDVstrain 852	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	22% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3958	Newcastle disease virus	NDVstrain 852	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	22% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3959	Newcastle disease virus	NDVstrain 776	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	40% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3960	Newcastle disease virus	NDVstrain 776	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3961	Newcastle disease virus	NDVstrain 776	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3962	Newcastle disease virus	NDVstrain 769	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	53% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3963	Newcastle disease virus	NDVstrain 769	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	60% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3964	Newcastle disease virus	NDVstrain 769	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	62% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3965	Newcastle disease virus	NDVstrain 860	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	59% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3966	Newcastle disease virus	NDVstrain 860	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	49% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3967	Newcastle disease virus	NDVstrain 860	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	40% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3968	Newcastle disease virus	NDVstrain 777	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	72 cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3969	Newcastle disease virus	NDVstrain 777	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	70% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3970	Newcastle disease virus	NDVstrain 777	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	60% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3971	Newcastle disease virus	NDVstrain 14	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	44% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3972	Newcastle disease virus	NDVstrain 14	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	39% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3973	Newcastle disease virus	NDVstrain 14	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	39% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3974	Newcastle disease virus	NDVstrain 718	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	59% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3975	Newcastle disease virus	NDVstrain 718	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	55% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3976	Newcastle disease virus	NDVstrain 718	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	49% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3977	Newcastle disease virus	NDVstrain 465	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	69% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3978	Newcastle disease virus	NDVstrain 465	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	61% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3979	Newcastle disease virus	NDVstrain 465	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	59% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3980	Newcastle disease virus	NDVstrain 922	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	79% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3981	Newcastle disease virus	NDVstrain 922	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	65% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3982	Newcastle disease virus	NDVstrain 922	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	52% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3983	Newcastle disease virus	NDVstrain 27	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	75% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3984	Newcastle disease virus	NDVstrain 27	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	65% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3985	Newcastle disease virus	NDVstrain 27	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	61% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3986	Newcastle disease virus	NDVstrain AD	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	63% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3987	Newcastle disease virus	NDVstrain AD	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	49% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3988	Newcastle disease virus	NDVstrain AD	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	46% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3989	Newcastle disease virus	NDVstrain 753	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	50% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3990	Newcastle disease virus	NDVstrain 753	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	50% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3991	Newcastle disease virus	NDVstrain 753	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	45% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3998	Newcastle disease virus	NDVwild 264	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	50% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_3999	Newcastle disease virus	NDVwild 264	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	45% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4000	Newcastle disease virus	NDVwild 264	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	45% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4010	Newcastle disease virus	NDVwild 320	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	35% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4011	Newcastle disease virus	NDVwild 320	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	37% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4012	Newcastle disease virus	NDVwild 320	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4022	Newcastle disease virus	NDVwild 321	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	50% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4023	Newcastle disease virus	NDVwild 321	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	45% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4024	Newcastle disease virus	NDVwild 321	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	44% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4034	Newcastle disease virus	NDVwild 373	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	59% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4035	Newcastle disease virus	NDVwild 373	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	59% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4036	Newcastle disease virus	NDVwild 373	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	59% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4046	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	30% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4047	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	42% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4048	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	39% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4058	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	45% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4059	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	20% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4060	Newcastle disease virus	NDVwild 852	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	20% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4070	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	2 HAU	40% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4071	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	8 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4072	Newcastle disease virus	NDVwild 776	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	10000 cells per well	NA	MTT assay	16 HAU	38% cell survival after 4th day	No	No	NA	No response	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4076	Newcastle disease virus	NDVwild 770	RNA	Paramyxoviridae	None	Yes	No	No	Research institute of fundamental and clinical immunology, Russia	Human non-small lung carcinoma cell line	A549	NA	NA	NA	NA	NA	SCID mice xenograft for A459 cell (3.5E+6)	16 HAU	NA	4.2 fold decrease in tumor size compared to control after 15th day	NA	Virus induces apoptosis, necrosis and autophagy in cancer cells	Induction of MARK signalling pathway	NA	29621357
OV_4111	Adenovirus	Ad-CCL20-CD40L	DNA	Adenoviridae	Addition of CCL20 and CD40L gene near by TERT promoter	Yes	No	virus expressing CCL20 chemokine gene	ATCC	Human lung cancer cell line	A549	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	90% cell survival after 7 days	No	No	NA	No response	NA	NA	NA	NA	26208317
OV_4194	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Cell bank of chinese academy of science	Human lung adenocarcinoma cell line	A549	1.0E+6 cells per well	NA	CCK-8 assay	100 MOI	100% cell viability after day 1	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4195	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Cell bank of chinese academy of science	Human lung adenocarcinoma cell line	A549	1.0E+6 cells per well	NA	CCK-8 assay	100 MOI	100% cell viability after day 2	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4196	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Cell bank of chinese academy of science	Human lung adenocarcinoma cell line	A549	1.0E+6 cells per well	NA	CCK-8 assay	100 MOI	100% cell viability after day 3	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4197	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Cell bank of chinese academy of science	Human lung adenocarcinoma cell line	A549	1.0E+6 cells per well	NA	CCK-8 assay	100 MOI	100% cell viability after day 4	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4198	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Cell bank of chinese academy of science	Human lung adenocarcinoma cell line	A549	1.0E+6 cells per well	NA	CCK-8 assay	100 MOI	100% cell viability after day 5	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4199	Adenovirus	Ad-CXCR4-DAL1	DNA	Adenoviridae	Virus expressing DAL-1 gene under promoter CXXR4	Yes	No	No	Cell bank of chinese academy of science	Human lung adenocarcinoma cell line	A549	1.0E+6 cells per well	NA	CCK-8 assay	100 MOI	100% cell viability after day 1	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4200	Adenovirus	Ad-CXCR4-DAL1	DNA	Adenoviridae	Virus expressing DAL-1 gene under promoter CXXR4	Yes	No	No	Cell bank of chinese academy of science	Human lung adenocarcinoma cell line	A549	1.0E+6 cells per well	NA	CCK-8 assay	100 MOI	100% cell viability after day 2	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4201	Adenovirus	Ad-CXCR4-DAL1	DNA	Adenoviridae	Virus expressing DAL-1 gene under promoter CXXR4	Yes	No	No	Cell bank of chinese academy of science	Human lung adenocarcinoma cell line	A549	1.0E+6 cells per well	NA	CCK-8 assay	100 MOI	100% cell viability after day 3	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4202	Adenovirus	Ad-CXCR4-DAL1	DNA	Adenoviridae	Virus expressing DAL-1 gene under promoter CXXR4	Yes	No	No	Cell bank of chinese academy of science	Human lung adenocarcinoma cell line	A549	1.0E+6 cells per well	NA	CCK-8 assay	100 MOI	100% cell viability after day 4	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4203	Adenovirus	Ad-CXCR4-DAL1	DNA	Adenoviridae	Virus expressing DAL-1 gene under promoter CXXR4	Yes	No	No	Cell bank of chinese academy of science	Human lung adenocarcinoma cell line	A549	1.0E+6 cells per well	NA	CCK-8 assay	100 MOI	10% cell viability after day 5	No	No	NA	No response	NA	Virus induce apoptosis process leads to cancer cell death	NA	NA	26280082
OV_4305	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human lung carcinoma	A549	4000 cells per well	NA	MTT assay	10 pfu	68.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4422	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	48% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4430	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	20% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4474	Adenovirus	oAD/DCN-shMet	DNA	Adenoviridae	Adenovirus conjugated with DCN and shMet	Yes	No	No	ATCC	Human lung carcinoma cell line	A549	70% confluence in 24 well plate	NA	MTT assay	1 MOI	65% cancer cell survivalability after 48 hours	No	No	NA	No response	NA	NA	Increased in IL-6 level to 140pg/ml compared to control 20 pg/ml	NA	26951927
OV_4475	Adenovirus	oAD/DCN-shMet/PP	DNA	Adenoviridae	Adenovirus conjugated with DCN, shMet and PEGylated at PAMAM	Yes	No	No	ATCC	Human lung carcinoma cell line	A549	70% confluence in 24 well plate	NA	MTT assay	1 MOI	58% cancer cell survivalability after 48 hours	No	No	NA	No response	NA	NA	Increased in IL-6 level to 40pg/ml compared to control 20 pg/ml	NA	26951927
OV_4476	Adenovirus	oAD/DCN-shMet/PPE	DNA	Adenoviridae	Adenovirus conjugated with DCN, shMet and Erbitux-conjugated PEGylated at PAMAM	Yes	No	No	ATCC	Human lung carcinoma cell line	A549	70% confluence in 24 well plate	NA	MTT assay	1 MOI	18% cancer cell survivalability after 48 hours	No	No	NA	No response	NA	NA	Increased in IL-6 level to 40pg/ml compared to control 20 pg/ml	NA	26951927
OV_4539	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4540	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	97% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4541	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	97% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4542	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4543	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4544	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	82% cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4545	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	82% cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4546	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	72% cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4547	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	72% cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4548	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	60% cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4549	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	60% cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4550	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	50% cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4551	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	40% cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4552	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	42% cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4553	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	42% cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4554	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	35% cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4951	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	10 MOI	20% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4952	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	1 MOI	25% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4953	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	0.1 MOI	40% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4954	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	0.01 MOI	60% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4955	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	10 MOI	40% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4956	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	1 MOI	60% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4957	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	0.1 MOI	70% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4958	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	0.01 MOI	80% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4959	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	10 MOI	70% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4960	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	1 MOI	80% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4961	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	0.1 MOI	90% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4962	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	0.01 MOI	90% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4963	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	10 MOI	20% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4964	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	1 MOI	50% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4965	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	0.1 MOI	60% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4966	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	0.01 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4967	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	10 MOI	60% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4968	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	1 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4969	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	0.1 MOI	100% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4970	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	0.01 MOI	100% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_5016	Vaccinia virus	VG9	DNA	Poxviridae	None	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	55% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5017	Vaccinia virus	VG9	DNA	Poxviridae	None	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTT assay	1 MOI	42% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5018	Vaccinia virus	VG9	DNA	Poxviridae	None	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTT assay	10 MOI	30% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5019	Vaccinia virus	VG9-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	58% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5020	Vaccinia virus	VG9-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTT assay	1 MOI	44% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5021	Vaccinia virus	VG9-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTT assay	10 MOI	40% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5022	Vaccinia virus	WR-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	58% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5023	Vaccinia virus	WR-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTT assay	1 MOI	46% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5024	Vaccinia virus	WR-EGFP	DNA	Poxviridae	Addition of EGFP gene in tk locus	Yes	No	No	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTT assay	10 MOI	40% cell viability after 3 days	No	No	NA	No response	NA	NA	NA	NA	28465492
OV_5070	Avian orthoreovirus	ARV-PB1	RNA	Reoviridae	None	Yes	No	No	ATCC	Human lung carcinoma cell line	A549	1.0E+3 cells per well	NA	Crystal violet staining	10 MOI	80% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis	Induction of Interferon related gene expression	NA	28441762
OV_5108	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5109	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	80% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5110	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	50% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5111	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5112	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5113	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	100% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5114	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	60% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5115	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5339	Newcastle disease virus	LaSota	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human nonsmall cell lung carcinoma	A549	5.0E+4 cells per well	NA	MTT assay	0.001 MOI	16% cells remain viable after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	Induced production of IFN-alpha, IFN-beta, IL-6and IFN-gamma	NA	28293547
OV_5598	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human lung carcinoma cell line	A549	80% confluency	NA	MTT assay	13 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5891	Adenovirus	CGTG-602	DNA	Adenoviridae	Virus E1A promoter is replaced by human E2F1 promoter	Yes	No	No	ATCC	Human lung cancer cell line	A549	NA	NA	MTT assay	1 ×10⁴ pfu	80% of cancer cell death occurs after 100 days	No	No	NA	No response	NA	NA	NA	NA	US9410129