Browse By Cell Line Result Page of OvirusTdb
The total number of records retrieved from this search are 266. Click on ID to see further detail.
IDOV_19 | Virus nameAdenovirus | Virus strainoAd/DCN/LRP | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertional mutant for DCN and LRP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineGrown to 70% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result70% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInhibits Wnt/β-catenin and TGF-β1 signaling pathways | Immunogenic effectIL-6 production increased by 3 folds as compared to normal | Clinical trialNA | PMID26471393 |
IDOV_20 | Virus nameAdenovirus | Virus strainoAd/DCN/LRP | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertional mutant for DCN and LRP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineGrown to 70% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result58% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInhibits Wnt/β-catenin and TGF-β1 signaling pathways | Immunogenic effectIL-6 production increased by 3 folds as compared to normal | Clinical trialNA | PMID26471393 |
IDOV_21 | Virus nameAdenovirus | Virus strainoAd/DCN/LRP | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertional mutant for DCN and LRP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineGrown to 70% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result38% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInhibits Wnt/β-catenin and TGF-β1 signaling pathways | Immunogenic effectIL-6 production increased by 3 folds as compared to normal | Clinical trialNA | PMID26471393 |
IDOV_22 | Virus nameAdenovirus | Virus strainoAd/DCN/LRP-PEG | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertional mutant for DCN and LRP gene with polyethylene glycol | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineGrown to 70% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result100% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInhibits Wnt/β-catenin and TGF-β1 signaling pathways | Immunogenic effectNA | Clinical trialNA | PMID26471393 |
IDOV_23 | Virus nameAdenovirus | Virus strainoAd/DCN/LRP-PEG | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertional mutant for DCN and LRP gene with polyethylene glycol | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineGrown to 70% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result95% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInhibits Wnt/β-catenin and TGF-β1 signaling pathways | Immunogenic effectNA | Clinical trialNA | PMID26471393 |
IDOV_24 | Virus nameAdenovirus | Virus strainoAd/DCN/LRP-PEG | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertional mutant for DCN and LRP gene with polyethylene glycol | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineGrown to 70% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result94% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInhibits Wnt/β-catenin and TGF-β1 signaling pathways | Immunogenic effectNA | Clinical trialNA | PMID26471393 |
IDOV_25 | Virus nameAdenovirus | Virus strainoAd/DCN/LRP-PEG-NT | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineGrown to 70% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result77% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInhibits Wnt/β-catenin and TGF-β1 signaling pathways | Immunogenic effectNA | Clinical trialNA | PMID26471393 |
IDOV_26 | Virus nameAdenovirus | Virus strainoAd/DCN/LRP-PEG-NT | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineGrown to 70% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result72% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInhibits Wnt/β-catenin and TGF-β1 signaling pathways | Immunogenic effectNA | Clinical trialNA | PMID26471393 |
IDOV_27 | Virus nameAdenovirus | Virus strainoAd/DCN/LRP-PEG-NT | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycol | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineGrown to 70% confluence | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result58% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInhibits Wnt/β-catenin and TGF-β1 signaling pathways | Immunogenic effectNA | Clinical trialNA | PMID26471393 |
IDOV_40 | Virus nameAdenovirus | Virus strainAdCMV/GFP | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutant with E1 deletion carrying a green fluorescent protein (GFP) | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineDesnity of 1000000 in 60mm dish | In-vitro toxicityHighly toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI | AssayMTT assay | In-vitro virus concentration3.5 MOI | In-vitro result13% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26475304 |
IDOV_41 | Virus nameAdenovirus | Virus strainAd dl1520 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b mutant with 827-bp deletion and a point mutation with premature stop codon in the E1B55K coding region | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineDesnity of 1000000 in 60mm dish | In-vitro toxicityMinimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI | AssayMTT assay | In-vitro virus concentration3.5 MOI | In-vitro result54% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26475304 |
IDOV_42 | Virus nameAdenovirus | Virus strainAd-cycE | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassette | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineDesnity of 1000000 in 60mm dish | In-vitro toxicityMinimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI | AssayMTT assay | In-vitro virus concentration3.5 MOI | In-vitro result18% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectActivates CDK2 and targets the transcriptional repressor pRb | Clinical trialNA | PMID26475304 |
IDOV_47 | Virus nameAdenovirus | Virus strainAd5WS1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the E1 promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result57% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_48 | Virus nameAdenovirus | Virus strainAd5WS1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the E1 promoter | Virus aloneNo | Virus in combination with drug/radiationViral strain in combination with etoposide (0.5 μg/ml) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicity0.67 CDI | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result24% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_49 | Virus nameAdenovirus | Virus strainAd5WS1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the E1 promoter | Virus aloneNo | Virus in combination with drug/radiationViral strain in combination with epirubicin (0.5 μg/ml) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicity0.46 CDI | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result16% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_50 | Virus nameAdenovirus | Virus strainAd5WS1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the E1 promoter | Virus aloneNo | Virus in combination with drug/radiationViral strain in combination with doxorubicin (0.1 μg/ml) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicity0.88 CDI | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result26% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_51 | Virus nameAdenovirus | Virus strainAd5WS1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the E1 promoter | Virus aloneNo | Virus in combination with drug/radiationViral strain in combination with vincristine (0.1 μg/ml) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicity0.79 CDI | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result25% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_52 | Virus nameAdenovirus | Virus strainAd5WS1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the E1 promoter | Virus aloneNo | Virus in combination with drug/radiationViral strain in combination with colchcine (0.02 μg/ml) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicity0.81 CDI | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result28% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_53 | Virus nameAdenovirus | Virus strainAd5GS3 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the MDR1 promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result18% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_54 | Virus nameAdenovirus | Virus strainAd5GS3 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the MDR1 promoter | Virus aloneNo | Virus in combination with drug/radiationViral strain in combination with etoposide (0.5 μg/ml) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicity0.27 CDI | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result4% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_55 | Virus nameAdenovirus | Virus strainAd5GS3 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the MDR1 promoter | Virus aloneNo | Virus in combination with drug/radiationViral strain in combination with epirubicin (0.5 μg/ml) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicity0.31 CDI | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result4% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_56 | Virus nameAdenovirus | Virus strainAd5GS3 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the MDR1 promoter | Virus aloneNo | Virus in combination with drug/radiationViral strain in combination with doxorubicin (0.1 μg/ml) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicity0.33 CDI | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result6% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_57 | Virus nameAdenovirus | Virus strainAd5GS3 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the MDR1 promoter | Virus aloneNo | Virus in combination with drug/radiationViral strain in combination with vincristine (0.1 μg/ml) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicity0.89 CDI | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result12% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_58 | Virus nameAdenovirus | Virus strainAd5GS3 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1B55K-deleted mutant driven by the MDR1 promoter | Virus aloneNo | Virus in combination with drug/radiationViral strain in combination with colchcine (0.02 μg/ml) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicity0.78 CDI | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result10% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26515462 |
IDOV_314 | Virus nameAdenovirus | Virus strainAd.sp-E1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationViral E1A promoter was replaced by human survivin promoter (hsurP) | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result28% cancer cell viability at 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26554307 |
IDOV_315 | Virus nameAdenovirus | Virus strainAd.4N1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationViral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result78% cancer cell viability at 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduces apoptosis by upregulating Bax and activated caspase 3 levels | Immunogenic effectInduces expression of IL-24 | Clinical trialNA | PMID26554307 |
IDOV_316 | Virus nameAdenovirus | Virus strainAd.4N1-IL24 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationViral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result24% cancer cell viability at 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduces apoptosis by upregulating Bax and activated caspase 3 levels | Immunogenic effectInduces expression of IL-24 | Clinical trialNA | PMID26554307 |
IDOV_317 | Virus nameAdenovirus | Virus strainAd.sp-E1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationViral E1A promoter was replaced by human survivin promoter (hsurP) | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result24% cancer cell viability at 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26554307 |
IDOV_318 | Virus nameAdenovirus | Virus strainAd.4N1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationViral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result57% cancer cell viability at 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduces apoptosis by upregulating Bax and activated caspase 3 levels | Immunogenic effectInduces expression of IL-24 | Clinical trialNA | PMID26554307 |
IDOV_319 | Virus nameAdenovirus | Virus strainAd.4N1-IL24 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationViral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result18% cancer cell viability at 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduces apoptosis by upregulating Bax and activated caspase 3 levels | Immunogenic effectInduces expression of IL-24 | Clinical trialNA | PMID26554307 |
IDOV_320 | Virus nameAdenovirus | Virus strainAd.sp-E1A | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationViral E1A promoter was replaced by human survivin promoter (hsurP) | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result22% cancer cell viability at 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26554307 |
IDOV_321 | Virus nameAdenovirus | Virus strainAd.4N1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationViral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result45% cancer cell viability at 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduces apoptosis by upregulating Bax and activated caspase 3 levels | Immunogenic effectInduces expression of IL-24 | Clinical trialNA | PMID26554307 |
IDOV_322 | Virus nameAdenovirus | Virus strainAd.4N1-IL24 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationViral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result11% cancer cell viability at 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduces apoptosis by upregulating Bax and activated caspase 3 levels | Immunogenic effectInduces expression of IL-24 | Clinical trialNA | PMID26554307 |
IDOV_326 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration1 MOI | In-vitro result1% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_330 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration2.5 MOI | In-vitro result10% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_334 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration5 MOI | In-vitro result92% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_338 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro result92% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_342 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration20 MOI | In-vitro result100% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_345 | Virus nameAdenovirus | Virus strainAdLacZ | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1/E3-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result58% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_348 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with temozolomide (TMZ) - 0.6 mM | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2.5 MOI | In-vitro result18% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedJNK activation induces autophagy | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_351 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result49% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_352 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result26% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_353 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with temozolomide (TMZ) and 3-MA at -0.75 mM and 10 mM concentration, respectively | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result62% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedJNK activation induces autophagy (Autophagy effect slightly inhibited by 3-MA) | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_354 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with temozolomide (TMZ) and 3-MA at -0.75 mM and 10 mM concentration, respectively | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result44% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedJNK activation induces autophagy (Autophagy effect slightly inhibited by 3-MA) | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_355 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with temozolomide (TMZ) and BAF-A1 at -0.75 mM and 10 nM concentration, respectively | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result65% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedJNK activation induces autophagy (Autophagy effect slightly inhibited by Baf-A1) | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_356 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with temozolomide (TMZ) and BAF-A1 at -0.75 mM and 10 nM concentration, respectively | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result47% cancer cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedJNK activation induces autophagy (Autophagy effect slightly inhibited by Baf-A1) | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_1444 | Virus nameReovirus | Virus strainReoT3D | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNCI | Origin of cell lineHuman NSCLC cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayXTT assay | In-vitro virus concentrationLog10 pfu/cell | In-vitro resultLess than 10% cell survived 48 hours after post infection | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis, activation of caspase 3 | Immunogenic effectNA | Clinical trialNA | PMID19594950 |
IDOV_2077 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineNA | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.1 MOI | In-vitro resultSome cell death observed | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of senescence | Immunogenic effectNA | Clinical trialNA | PMID21794078 |
IDOV_2078 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineNA | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration1 MOI | In-vitro resultAll cells was dead | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of senescence | Immunogenic effectNA | Clinical trialNA | PMID21794078 |
IDOV_2079 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineNA | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro resultAll cells was dead | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of senescence | Immunogenic effectNA | Clinical trialNA | PMID21794078 |
IDOV_2080 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineNA | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration100 MOI | In-vitro resultAll cells was dead | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21794078 |
IDOV_2106 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of AFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineATCC | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.1 MOI | In-vitro resultSome cell death observed | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID21979578 |
IDOV_2107 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of AFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineATCC | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration1 MOI | In-vitro resultSome cell death observed | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID21979578 |
IDOV_2108 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of AFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineATCC | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro resultSome cell death observed | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID21979578 |
IDOV_2109 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of AFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineATCC | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration100 MOI | In-vitro resultMost of the cells are died | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID21979578 |
IDOV_2126 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineATCC | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.1 MOI | In-vitro resultSome cell death observed | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID21979578 |
IDOV_2127 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineATCC | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration1 MOI | In-vitro resultSome cell death observed | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID21979578 |
IDOV_2128 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineATCC | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro resultSome cell death observed | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID21979578 |
IDOV_2129 | Virus nameAdenovirus | Virus strainMutant | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of E1BK55KD gene and addition of TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing TRAIL gene | Source of cell lineATCC | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration100 MOI | In-vitro resultSome cell death observed | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID21979578 |
IDOV_2211 | Virus nameNewcastle disease virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin | Immune gene insertion in viral genomeNo | Source of cell lineChinese academy of sciece | Origin of cell lineHuman small cell lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/c nude mice xenograft for A549 cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreased to 500mm after 57 days | Mode of deliveryIntratumoral | Pathway inducedInduction of caspase and apoptotic pathway as detected by Hoechst staining and TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID22095029 |
IDOV_2780 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.1 MOI | In-vitro resultNo cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2781 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.5 MOI | In-vitro resultNo cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2782 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration1 MOI | In-vitro resultNo cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2783 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration5 MOI | In-vitro resultModerate cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2784 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro resultAll cell was dead | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2795 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result90% cells are viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2796 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result90% cells are viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2797 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result80% cells are viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2798 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result70% cells are viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2799 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result50% cells are viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2805 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/c nude mice xenograft for A549 | In-vivo virus concentration5.0E+8 pfu | In-vivo toxicityNA | In-vivo resultSignificant reduction in tumor volume and increased in survival rate fro 15% to 87% at day 60 | Mode of deliveryIntratumoral | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2844 | Virus nameMeasles virus | Virus strainAttenuated strain | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayCell death detection kit | In-vitro virus concentration1 MOI | In-vitro result28% cells survived | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedActivation of caspase-3 | Immunogenic effectNA | Clinical trialNA | PMID23586034 |
IDOV_2852 | Virus nameMeasles virus | Virus strainAttenuated strain | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismRJ:NMRI nude mice xenograft for A549 cell line (1.5E+7) | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultSignificant reduction in tumor volume after 42 days | Mode of deliveryIntratumoral | Pathway inducedActivation of caspase-3 | Immunogenic effectNA | Clinical trialNA | PMID23586034 |
IDOV_2934 | Virus nameNewcastle disease virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationExpressing rl gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell linePeking university china | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/c nude mice xenograft for A549 cell line (6.3E+8) | In-vivo virus concentration6.3E+8 pfu | In-vivo toxicityNA | In-vivo resultTumor volume regressed to 274 +/- 114.20 compared to control 271.78 +/- 110.79 after day 1 | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis by virus | Immunogenic effectNA | Clinical trialNA | PMID25364430 |
IDOV_2935 | Virus nameNewcastle disease virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationExpressing rl gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell linePeking university china | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/c nude mice xenograft for A549 cell line (6.3E+8) | In-vivo virus concentration6.3E+8 pfu | In-vivo toxicityNA | In-vivo resultTumor volume regressed to 444.18 +/- 111.22 compared to control 591.45 +/- 244.50 after day 7 | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis by virus | Immunogenic effectNA | Clinical trialNA | PMID25364430 |
IDOV_2936 | Virus nameNewcastle disease virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationExpressing rl gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell linePeking university china | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/c nude mice xenograft for A549 cell line (6.3E+8) | In-vivo virus concentration6.3E+8 pfu | In-vivo toxicityNA | In-vivo resultTumor volume regressed to 657.56 +/- 176.74 compared to control 1483.21 +/- 446.75 after 14 day | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis by virus | Immunogenic effectNA | Clinical trialNA | PMID25364430 |
IDOV_2937 | Virus nameNewcastle disease virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationExpressing rl gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell linePeking university china | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBALB/c nude mice xenograft for A549 cell line (6.3E+8) | In-vivo virus concentration6.3E+8 pfu | In-vivo toxicityNA | In-vivo resultTumor volume regressed to 804.96 +/- 176.74 compared to control 1127.88 +/- 274.09 after 21 days | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis by virus | Immunogenic effectNA | Clinical trialNA | PMID25364430 |
IDOV_3051 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result18% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3052 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3053 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result1% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3081 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3082 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result15% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3083 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result5% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3464 | Virus nameAdenovirus | Virus strainAdenovirus CRAds | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell collection centre china | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration100 MOI | In-vitro result22% inhibition in tumor inhibition | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28638457 |
IDOV_3465 | Virus nameAdenovirus | Virus strainAdenovirus CRAds | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell collection centre china | Origin of cell lineHuman lung cancer cell line | Cell lineA549-DDPR cisplatin resistant | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration100 MOI | In-vitro result55% inhibition in tumor inhibition | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28638457 |
IDOV_3498 | Virus nameAdenovirus | Virus strainAdenovirus CRAds | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell collection centre china | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c nude mice xenograft for SW-620 cell line (1.0E+6) | In-vivo virus concentration8.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor size regressed to 700mm compared to control 900mm after 65 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28638457 |
IDOV_3499 | Virus nameAdenovirus | Virus strainAdenovirus CRAds | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin | Immune gene insertion in viral genomeNo | Source of cell lineCell collection centre china | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c nude mice xenograft for SW-620 cell line (1.0E+6) | In-vivo virus concentration8.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor size regressed to 100mm compared to control 900mm after 65 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28638457 |
IDOV_3500 | Virus nameAdenovirus | Virus strainAdenovirus CRAds | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell collection centre china | Origin of cell lineHuman lung cancer cell line | Cell lineA549-DDPR cisplatin resistant | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c nude mice xenograft for SW-620 cell line (1.0E+6) | In-vivo virus concentration8.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor size regressed to 800mm compared to control 900mm after 65 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28638457 |
IDOV_3501 | Virus nameAdenovirus | Virus strainAdenovirus CRAds | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin | Immune gene insertion in viral genomeNo | Source of cell lineCell collection centre china | Origin of cell lineHuman lung cancer cell line | Cell lineA549-DDPR cisplatin resistant | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c nude mice xenograft for SW-620 cell line (1.0E+6) | In-vivo virus concentration8.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor size regressed to 300mm compared to control 900mm after 65 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28638457 |
IDOV_3711 | Virus nameEnterovirus | Virus strainECHO-7 virus stain Rigvir | Virus genome typeRNA | Virus familyPicornaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell linePublic health england | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayLive cell imaging system | In-vitro virus concentration1% virus concentration | In-vitro result92% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29581783 |
IDOV_3718 | Virus nameEnterovirus | Virus strainECHO-7 virus stain Rigvir | Virus genome typeRNA | Virus familyPicornaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell linePublic health england | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayLive cell imaging system | In-vitro virus concentration10% virus concentration | In-vitro result91% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID29581783 |
IDOV_3831 | Virus nameNewcastle disease virus | Virus strainNDVstrain 852 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result23% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3832 | Virus nameNewcastle disease virus | Virus strainNDVstrain 320 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result34% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3833 | Virus nameNewcastle disease virus | Virus strainNDVstrain 264 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result35% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3834 | Virus nameNewcastle disease virus | Virus strainNDVstrain 776 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result38% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3835 | Virus nameNewcastle disease virus | Virus strainNDVstrain 770 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result39% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3836 | Virus nameNewcastle disease virus | Virus strainNDVstrain 14 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result40% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3837 | Virus nameNewcastle disease virus | Virus strainNDVstrain 860 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result40% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3838 | Virus nameNewcastle disease virus | Virus strainNDVstrain 753 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result40% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3839 | Virus nameNewcastle disease virus | Virus strainNDVstrain AD | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result42% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3840 | Virus nameNewcastle disease virus | Virus strainNDVstrain 321 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result42% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3841 | Virus nameNewcastle disease virus | Virus strainNDVstrain 718 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result50% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3842 | Virus nameNewcastle disease virus | Virus strainNDVstrain 922 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result50% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3843 | Virus nameNewcastle disease virus | Virus strainNDVstrain 373 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result58% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3844 | Virus nameNewcastle disease virus | Virus strainNDVstrain 53 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result60% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3845 | Virus nameNewcastle disease virus | Virus strainNDVstrain 777 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result60% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3846 | Virus nameNewcastle disease virus | Virus strainNDVstrain 27 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result61% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3847 | Virus nameNewcastle disease virus | Virus strainNDVstrain 769 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result61% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3848 | Virus nameNewcastle disease virus | Virus strainNDVstrain 12 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result70% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3849 | Virus nameNewcastle disease virus | Virus strainNDVstrain 945 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result78% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3850 | Virus nameNewcastle disease virus | Virus strainNDVstrain 49 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result80% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3851 | Virus nameNewcastle disease virus | Virus strainNDVstrain 52 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result81% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3852 | Virus nameNewcastle disease virus | Virus strainNDVstrain 746 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result90% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3853 | Virus nameNewcastle disease virus | Virus strainNDVstrain 465 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result90% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3854 | Virus nameNewcastle disease virus | Virus strainNDVstrain 429 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result90% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3855 | Virus nameNewcastle disease virus | Virus strainNDVstrain 329 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result97% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3856 | Virus nameNewcastle disease virus | Virus strainNDVstrain 339 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result98% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3857 | Virus nameNewcastle disease virus | Virus strainNDVstrain 389 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result98% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3858 | Virus nameNewcastle disease virus | Virus strainNDVstrain 48 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result100% cell viability after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3941 | Virus nameNewcastle disease virus | Virus strainNDVstrain 264 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result49% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3942 | Virus nameNewcastle disease virus | Virus strainNDVstrain 264 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result36% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3943 | Virus nameNewcastle disease virus | Virus strainNDVstrain 264 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result34% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3944 | Virus nameNewcastle disease virus | Virus strainNDVstrain 320 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result30% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3945 | Virus nameNewcastle disease virus | Virus strainNDVstrain 320 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result33% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3946 | Virus nameNewcastle disease virus | Virus strainNDVstrain 320 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result34% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3947 | Virus nameNewcastle disease virus | Virus strainNDVstrain 321 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result51% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3948 | Virus nameNewcastle disease virus | Virus strainNDVstrain 321 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result47% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3949 | Virus nameNewcastle disease virus | Virus strainNDVstrain 321 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result46% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3950 | Virus nameNewcastle disease virus | Virus strainNDVstrain 373 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result58% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3951 | Virus nameNewcastle disease virus | Virus strainNDVstrain 373 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result59% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3952 | Virus nameNewcastle disease virus | Virus strainNDVstrain 373 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result57% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3953 | Virus nameNewcastle disease virus | Virus strainNDVstrain 770 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result34% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3954 | Virus nameNewcastle disease virus | Virus strainNDVstrain 770 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result45% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3955 | Virus nameNewcastle disease virus | Virus strainNDVstrain 770 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result40% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3956 | Virus nameNewcastle disease virus | Virus strainNDVstrain 852 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result44% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3957 | Virus nameNewcastle disease virus | Virus strainNDVstrain 852 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result22% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3958 | Virus nameNewcastle disease virus | Virus strainNDVstrain 852 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result22% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3959 | Virus nameNewcastle disease virus | Virus strainNDVstrain 776 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result40% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3960 | Virus nameNewcastle disease virus | Virus strainNDVstrain 776 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result38% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3961 | Virus nameNewcastle disease virus | Virus strainNDVstrain 776 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result38% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3962 | Virus nameNewcastle disease virus | Virus strainNDVstrain 769 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result53% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3963 | Virus nameNewcastle disease virus | Virus strainNDVstrain 769 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result60% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3964 | Virus nameNewcastle disease virus | Virus strainNDVstrain 769 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result62% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3965 | Virus nameNewcastle disease virus | Virus strainNDVstrain 860 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result59% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3966 | Virus nameNewcastle disease virus | Virus strainNDVstrain 860 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result49% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3967 | Virus nameNewcastle disease virus | Virus strainNDVstrain 860 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result40% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3968 | Virus nameNewcastle disease virus | Virus strainNDVstrain 777 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result72 cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3969 | Virus nameNewcastle disease virus | Virus strainNDVstrain 777 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result70% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3970 | Virus nameNewcastle disease virus | Virus strainNDVstrain 777 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result60% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3971 | Virus nameNewcastle disease virus | Virus strainNDVstrain 14 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result44% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3972 | Virus nameNewcastle disease virus | Virus strainNDVstrain 14 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result39% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3973 | Virus nameNewcastle disease virus | Virus strainNDVstrain 14 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result39% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3974 | Virus nameNewcastle disease virus | Virus strainNDVstrain 718 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result59% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3975 | Virus nameNewcastle disease virus | Virus strainNDVstrain 718 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result55% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3976 | Virus nameNewcastle disease virus | Virus strainNDVstrain 718 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result49% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3977 | Virus nameNewcastle disease virus | Virus strainNDVstrain 465 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result69% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3978 | Virus nameNewcastle disease virus | Virus strainNDVstrain 465 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result61% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3979 | Virus nameNewcastle disease virus | Virus strainNDVstrain 465 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result59% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3980 | Virus nameNewcastle disease virus | Virus strainNDVstrain 922 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result79% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3981 | Virus nameNewcastle disease virus | Virus strainNDVstrain 922 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result65% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3982 | Virus nameNewcastle disease virus | Virus strainNDVstrain 922 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result52% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3983 | Virus nameNewcastle disease virus | Virus strainNDVstrain 27 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result75% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3984 | Virus nameNewcastle disease virus | Virus strainNDVstrain 27 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result65% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3985 | Virus nameNewcastle disease virus | Virus strainNDVstrain 27 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result61% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3986 | Virus nameNewcastle disease virus | Virus strainNDVstrain AD | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result63% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3987 | Virus nameNewcastle disease virus | Virus strainNDVstrain AD | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result49% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3988 | Virus nameNewcastle disease virus | Virus strainNDVstrain AD | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result46% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3989 | Virus nameNewcastle disease virus | Virus strainNDVstrain 753 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result50% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3990 | Virus nameNewcastle disease virus | Virus strainNDVstrain 753 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result50% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3991 | Virus nameNewcastle disease virus | Virus strainNDVstrain 753 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result45% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3998 | Virus nameNewcastle disease virus | Virus strainNDVwild 264 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result50% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_3999 | Virus nameNewcastle disease virus | Virus strainNDVwild 264 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result45% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4000 | Virus nameNewcastle disease virus | Virus strainNDVwild 264 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result45% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4010 | Virus nameNewcastle disease virus | Virus strainNDVwild 320 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result35% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4011 | Virus nameNewcastle disease virus | Virus strainNDVwild 320 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result37% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4012 | Virus nameNewcastle disease virus | Virus strainNDVwild 320 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result38% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4022 | Virus nameNewcastle disease virus | Virus strainNDVwild 321 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result50% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4023 | Virus nameNewcastle disease virus | Virus strainNDVwild 321 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result45% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4024 | Virus nameNewcastle disease virus | Virus strainNDVwild 321 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result44% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4034 | Virus nameNewcastle disease virus | Virus strainNDVwild 373 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result59% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4035 | Virus nameNewcastle disease virus | Virus strainNDVwild 373 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result59% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4036 | Virus nameNewcastle disease virus | Virus strainNDVwild 373 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result59% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4046 | Virus nameNewcastle disease virus | Virus strainNDVwild 770 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result30% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4047 | Virus nameNewcastle disease virus | Virus strainNDVwild 770 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result42% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4048 | Virus nameNewcastle disease virus | Virus strainNDVwild 770 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result39% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4058 | Virus nameNewcastle disease virus | Virus strainNDVwild 852 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result45% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4059 | Virus nameNewcastle disease virus | Virus strainNDVwild 852 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result20% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4060 | Virus nameNewcastle disease virus | Virus strainNDVwild 852 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result20% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4070 | Virus nameNewcastle disease virus | Virus strainNDVwild 776 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 HAU | In-vitro result40% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4071 | Virus nameNewcastle disease virus | Virus strainNDVwild 776 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration8 HAU | In-vitro result38% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4072 | Virus nameNewcastle disease virus | Virus strainNDVwild 776 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell line10000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration16 HAU | In-vitro result38% cell survival after 4th day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4076 | Virus nameNewcastle disease virus | Virus strainNDVwild 770 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineResearch institute of fundamental and clinical immunology, Russia | Origin of cell lineHuman non-small lung carcinoma cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismSCID mice xenograft for A459 cell (3.5E+6) | In-vivo virus concentration16 HAU | In-vivo toxicityNA | In-vivo result4.2 fold decrease in tumor size compared to control after 15th day | Mode of deliveryNA | Pathway inducedVirus induces apoptosis, necrosis and autophagy in cancer cells | Immunogenic effectInduction of MARK signalling pathway | Clinical trialNA | PMID29621357 |
IDOV_4111 | Virus nameAdenovirus | Virus strainAd-CCL20-CD40L | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAddition of CCL20 and CD40L gene near by TERT promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomevirus expressing CCL20 chemokine gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result90% cell survival after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26208317 |
IDOV_4194 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell bank of chinese academy of science | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayCCK-8 assay | In-vitro virus concentration100 MOI | In-vitro result100% cell viability after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26280082 |
IDOV_4195 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell bank of chinese academy of science | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayCCK-8 assay | In-vitro virus concentration100 MOI | In-vitro result100% cell viability after day 2 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26280082 |
IDOV_4196 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell bank of chinese academy of science | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayCCK-8 assay | In-vitro virus concentration100 MOI | In-vitro result100% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26280082 |
IDOV_4197 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell bank of chinese academy of science | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayCCK-8 assay | In-vitro virus concentration100 MOI | In-vitro result100% cell viability after day 4 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26280082 |
IDOV_4198 | Virus nameAdenovirus | Virus strainwild type | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell bank of chinese academy of science | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayCCK-8 assay | In-vitro virus concentration100 MOI | In-vitro result100% cell viability after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26280082 |
IDOV_4199 | Virus nameAdenovirus | Virus strainAd-CXCR4-DAL1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressing DAL-1 gene under promoter CXXR4 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell bank of chinese academy of science | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayCCK-8 assay | In-vitro virus concentration100 MOI | In-vitro result100% cell viability after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26280082 |
IDOV_4200 | Virus nameAdenovirus | Virus strainAd-CXCR4-DAL1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressing DAL-1 gene under promoter CXXR4 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell bank of chinese academy of science | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayCCK-8 assay | In-vitro virus concentration100 MOI | In-vitro result100% cell viability after day 2 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26280082 |
IDOV_4201 | Virus nameAdenovirus | Virus strainAd-CXCR4-DAL1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressing DAL-1 gene under promoter CXXR4 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell bank of chinese academy of science | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayCCK-8 assay | In-vitro virus concentration100 MOI | In-vitro result100% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26280082 |
IDOV_4202 | Virus nameAdenovirus | Virus strainAd-CXCR4-DAL1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressing DAL-1 gene under promoter CXXR4 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell bank of chinese academy of science | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayCCK-8 assay | In-vitro virus concentration100 MOI | In-vitro result100% cell viability after day 4 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26280082 |
IDOV_4203 | Virus nameAdenovirus | Virus strainAd-CXCR4-DAL1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressing DAL-1 gene under promoter CXXR4 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCell bank of chinese academy of science | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayCCK-8 assay | In-vitro virus concentration100 MOI | In-vitro result10% cell viability after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis process leads to cancer cell death | Immunogenic effectNA | Clinical trialNA | PMID26280082 |
IDOV_4305 | Virus nameAlphavirus | Virus strainM1 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung carcinoma | Cell lineA549 | Concentration of cell line4000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 pfu | In-vitro result68.2 % cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis | Immunogenic effectNA | Clinical trialNA | PMID26373347 |
IDOV_4422 | Virus nameVesicular stomatitis virus | Virus strainRdB | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationVirus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.2E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration21:1 particle to pfu | In-vitro result48% cell survival after 4 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26430798 |
IDOV_4430 | Virus nameVesicular stomatitis virus | Virus strainRdB-1L-VSVG | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationVirus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.2E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration24:1 particle to pfu | In-vitro result20% cell survival after 4 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26430798 |
IDOV_4474 | Virus nameAdenovirus | Virus strainoAD/DCN-shMet | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAdenovirus conjugated with DCN and shMet | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line70% confluence in 24 well plate | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result65% cancer cell survivalability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectIncreased in IL-6 level to 140pg/ml compared to control 20 pg/ml | Clinical trialNA | PMID26951927 |
IDOV_4475 | Virus nameAdenovirus | Virus strainoAD/DCN-shMet/PP | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAdenovirus conjugated with DCN, shMet and PEGylated at PAMAM | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line70% confluence in 24 well plate | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result58% cancer cell survivalability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectIncreased in IL-6 level to 40pg/ml compared to control 20 pg/ml | Clinical trialNA | PMID26951927 |
IDOV_4476 | Virus nameAdenovirus | Virus strainoAD/DCN-shMet/PPE | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationAdenovirus conjugated with DCN, shMet and Erbitux-conjugated PEGylated at PAMAM | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line70% confluence in 24 well plate | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result18% cancer cell survivalability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectIncreased in IL-6 level to 40pg/ml compared to control 20 pg/ml | Clinical trialNA | PMID26951927 |
IDOV_4539 | Virus nameAdenovirus | Virus strainCD55-TRAIL+ CD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIl and MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4540 | Virus nameAdenovirus | Virus strainCD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result97% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4541 | Virus nameAdenovirus | Virus strainCD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result97% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4542 | Virus nameAdenovirus | Virus strainCD55-TRAIL-IETD-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result90% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4543 | Virus nameAdenovirus | Virus strainCD55-TRAIL+ CD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIl and MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result90% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4544 | Virus nameAdenovirus | Virus strainCD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result82% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4545 | Virus nameAdenovirus | Virus strainCD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result82% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4546 | Virus nameAdenovirus | Virus strainCD55-TRAIL-IETD-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result72% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4547 | Virus nameAdenovirus | Virus strainCD55-TRAIL+ CD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIl and MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result72% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4548 | Virus nameAdenovirus | Virus strainCD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result60% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4549 | Virus nameAdenovirus | Virus strainCD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result60% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4550 | Virus nameAdenovirus | Virus strainCD55-TRAIL-IETD-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result50% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4551 | Virus nameAdenovirus | Virus strainCD55-TRAIL+ CD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIl and MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4552 | Virus nameAdenovirus | Virus strainCD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result42% cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4553 | Virus nameAdenovirus | Virus strainCD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result42% cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4554 | Virus nameAdenovirus | Virus strainCD55-TRAIL-IETD-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result35% cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4951 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4952 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result25% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4953 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4954 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result60% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4955 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4956 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4957 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4958 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result80% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4959 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4960 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result80% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4961 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result90% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4962 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result90% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4963 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4964 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result50% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4965 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4966 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result80% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4967 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4968 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result70% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4969 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4970 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_5016 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result55% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5017 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result42% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5018 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result30% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5019 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result58% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5020 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result44% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5021 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5022 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result58% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5023 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result46% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5024 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5070 | Virus nameAvian orthoreovirus | Virus strainARV-PB1 | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line1.0E+3 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro result80% cell viability after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectInduction of Interferon related gene expression | Clinical trialNA | PMID28441762 |
IDOV_5108 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5109 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.01 MOI | In-vitro result80% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5110 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5111 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5112 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5113 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5114 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5115 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5339 | Virus nameNewcastle disease virus | Virus strainLaSota | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman nonsmall cell lung carcinoma | Cell lineA549 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.001 MOI | In-vitro result16% cells remain viable after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis | Immunogenic effectInduced production of IFN-alpha, IFN-beta, IL-6and IFN-gamma | Clinical trialNA | PMID28293547 |
IDOV_5598 | Virus nameNewcastle disease virus | Virus strainNDV-MK107 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung carcinoma cell line | Cell lineA549 | Concentration of cell line80% confluency | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration13 pfu | In-vitro result50% of cancer cell death occurs | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectInduction of IFN-Gamma production | Clinical trialNA | PMIDUS7470426 |
IDOV_5891 | Virus nameAdenovirus | Virus strainCGTG-602 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus E1A promoter is replaced by human E2F1 promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 ×10ⴠpfu | In-vitro result80% of cancer cell death occurs after 100 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS9410129 |