Detailed description page of Selected OV_ID


OV_54 details
Primary information
OV_IDOV_54
Virus Name Adenovirus
StrainAd5GS3
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeE1B55K-deleted mutant driven by the MDR1 promoter
Virus aloneNo
Virus in combination iwth drug/radiationViral strain in combination with etoposide (0.5 μg/ml)
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineHuman lung cancer cell line
Cell lineA549
Concentration of cell line1
In-vitro toxicity0.27 CDI
AssayMTT assay
In-vitro virus concentration0.1 MOI
In-vitro result4% cancer cell viability
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26515462