Detailed description page of Selected OV_ID


OV_2077 details
Primary information
OV_IDOV_2077
Virus Name Adenovirus
StrainMutant
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing IL-24 gene
Source of cell lineNA
Origin of cell lineHuman lung adenocarcinoma cell line
Cell lineA549
Concentration of cell line0
In-vitro toxicityNA
AssayCrystal violet staining
In-vitro virus concentration0.1 MOI
In-vitro resultSome cell death observed
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of senescence
Immunogenic effectNA
Clinical trialNA
PMID21794078