Detailed description page of Selected OV_ID


OV_4966 details
Primary information
OV_IDOV_4966
Virus Name Vaccinia virus
Strainvv-IL-24
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeInsertion of IL-24 gene in tk locus
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing IL-24 gene
Source of cell lineShanghai cell collection
Origin of cell lineHuman lung cancer cell line
Cell lineA549
Concentration of cell line0
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration0.01 MOI
In-vitro result80% cell viability after 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis
Immunogenic effectNA
Clinical trialNA
PMID27208781