| Primary information |
|---|
| OV_ID | OV_5070 |
| Virus Name | Avian orthoreovirus |
| Strain | ARV-PB1 |
| Virus type | RNA |
| Virus family | Reoviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Human lung carcinoma cell line |
| Cell line | A549 |
| Concentration of cell line | 1 |
| In-vitro toxicity | NA |
| Assay | Crystal violet staining |
| In-vitro virus concentration | 10 MOI |
| In-vitro result | 80% cell viability after 96 hours |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Induction of apoptosis |
| Immunogenic effect | Induction of Interferon related gene expression |
| Clinical trial | NA |
| PMID | 28441762 |