Primary information |
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OV_ID | OV_4430 |
Virus Name | Vesicular stomatitis virus |
Strain | RdB-1L-VSVG |
Virus type | RNA |
Virus family | Rhabdoviridae |
Modification in virus genome | Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | ATCC |
Origin of cell line | Human lung cancer cell line |
Cell line | A549 |
Concentration of cell line | 1 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 24:1 particle to pfu |
In-vitro result | 20% cell survival after 4 days |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 26430798 |