Detailed description page of Selected OV_ID


OV_5022 details
Primary information
OV_IDOV_5022
Virus Name Vaccinia virus
StrainWR-EGFP
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeAddition of EGFP gene in tk locus
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman lung cancer cell line
Cell lineA549
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration0.1 MOI
In-vitro result58% cell viability after 3 days
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID28465492