Detailed description page of Selected OV_ID


OV_5114 details
Primary information
OV_IDOV_5114
Virus Name Vaccinia virus
Strainvvdd-tdTomato-mDAI
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeDeletion of tk gene and vaccinia growth gene and addition of murine DAI
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing murine DAI gene
Source of cell lineATCC
Origin of cell lineHuman lung cancer cell line
Cell lineA549
Concentration of cell line1
In-vitro toxicityNA
AssayMTS assay
In-vitro virus concentration0.1 MOI
In-vitro result60% cell viability
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectInduction of Immunogenic gene such as T cell activation
Clinical trialNA
PMID27626058