Detailed description page of Selected OV_ID


OV_57 details
Primary information
OV_IDOV_57
Virus Name Adenovirus
StrainAd5GS3
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeE1B55K-deleted mutant driven by the MDR1 promoter
Virus aloneNo
Virus in combination iwth drug/radiationViral strain in combination with vincristine (0.1 μg/ml)
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineHuman lung cancer cell line
Cell lineA549
Concentration of cell line1
In-vitro toxicity0.89 CDI
AssayMTT assay
In-vitro virus concentration0.1 MOI
In-vitro result12% cancer cell viability
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26515462