Detailed description page of Selected OV_ID


OV_41 details
Primary information
OV_IDOV_41
Virus Name Adenovirus
StrainAd dl1520
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeE1b mutant with 827-bp deletion and a point mutation with premature stop codon in the E1B55K coding region
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman lung cancer cell line
Cell lineA549
Concentration of cell line0
In-vitro toxicityMinimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI
AssayMTT assay
In-vitro virus concentration3.5 MOI
In-vitro result54% cancer cell viability
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26475304