Detailed description page of Selected OV_ID


OV_3500 details
Primary information
OV_IDOV_3500
Virus Name Adenovirus
StrainAdenovirus CRAds
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineCell collection centre china
Origin of cell lineHuman lung cancer cell line
Cell lineA549-DDPR cisplatin resistant
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBalb/c nude mice xenograft for SW-620 cell line (1 × 10⁶)
In-vivo virus concentration8 × 10⁶ pfu
In-vivo toxicityNA
In-vivo resultTumor size regressed to 800mm compared to control 900mm after 65 days
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID28638457