Detailed description page of Selected OV_ID


OV_4202 details
Primary information
OV_IDOV_4202
Virus Name Adenovirus
StrainAd-CXCR4-DAL1
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeVirus expressing DAL-1 gene under promoter CXXR4
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineCell bank of chinese academy of science
Origin of cell lineHuman lung adenocarcinoma cell line
Cell lineA549
Concentration of cell line1
In-vitro toxicityNA
AssayCCK-8 assay
In-vitro virus concentration100 MOI
In-vitro result100% cell viability after day 4
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induce apoptosis process leads to cancer cell death
Immunogenic effectNA
Clinical trialNA
PMID26280082