Detailed description page of Selected OV_ID


OV_4554 details
Primary information
OV_IDOV_4554
Virus Name Adenovirus
StrainCD55-TRAIL-IETD-MnSOD
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeVirus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineShanghai cell collection
Origin of cell lineHuman lung carcinoma cell line
Cell lineA549
Concentration of cell line5
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result35% cell survival after 96 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induced apoptosis
Immunogenic effectNA
Clinical trialNA
PMID27080225