Browse result page of AntiTbPdb
The total number entries retrieved from this search are 619
| ID | Name | Sequence | N-Terminal Modification | C-Terminal Modification | Chemical Modification | Linear/Cyclic | Length | Chirality | Nature | Source | Origin | Species | Strain | Inhibition Concentration | In vitro/ In vivo | Cell Line | Intracellular Inhibition | Cytotoxicity | Animal Model | Effective Dose in model organism | Immune Responce | Mechanism of Action | Target | Combination Therapy | Other Activities | Year of Publication | Pubmed ID/ Patent No. |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| antitb_1706 | Synthetic rabbit neytrophil (SNP-1) | not available | NA | NA | NA | NA | 0 | NA | Cationic | Natural | Rabbit neutrophil | Mycobacterium tuberculosis | Mycobacterium tuberculosis Ra 9034G | Reduction in CFU at 50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | Microbial membrane disruption | NA | NA | NA | 1996 | 8641802 |
| antitb_1707 | Synthetic rabbit neytrophil (SNP-1) | not available | NA | NA | NA | NA | 0 | NA | Cationic | Natural | Rabbit neutrophil | Mycobacterium tuberculosis | Mycobacterium tuberculosis Ra 11170G | Reduction in CFU at 50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | Microbial membrane disruption | NA | NA | NA | 1996 | 8641802 |
| antitb_1708 | Porcine leucocyte peptide (PG-1) | RGGRLCYCRRRFCVCVGR | Free | Free | Disulphide linkage 6-15 and 8-13 | Cyclic | 18 | L | Cationic | Natural | porcine neutrophil leucocyte | Mycobacterium tuberculosis | Mycobacterium tuberculosis Ra 7632G | Reduction in CFU at 50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | Microbial membrane disruption | NA | NA | NA | 1996 | 8641802 |
| antitb_1709 | Porcine leucocyte peptide (PG-1) | RGGRLCYCRRRFCVCVGR | Free | Free | Disulphide linkage 6-15 and 8-14 | Cyclic | 18 | L | Cationic | Natural | porcine neutrophil leucocyte | Mycobacterium tuberculosis | Mycobacterium tuberculosis Ra 9034G | Reduction in CFU at 50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | Microbial membrane disruption | NA | NA | NA | 1996 | 8641802 |
| antitb_1710 | Porcine leucocyte peptide (PG-1) | RGGRLCYCRRRFCVCVGR | Free | Free | Disulphide linkage 6-15 and 8-15 | Cyclic | 18 | L | Cationic | Natural | porcine neutrophil leucocyte | Mycobacterium tuberculosis | Mycobacterium tuberculosis Ra 11170G | Reduction in CFU at 50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | Microbial membrane disruption | NA | NA | NA | 1996 | 8641802 |
| antitb_1711 | Porcine leucocyte peptide (PG-1) | RGGRLCYCRRRFCVCVGR | Free | Free | Disulphide linkage 6-15 and 8-16 | Cyclic | 18 | L | Cationic | Natural | porcine neutrophil leucocyte | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37 Ra | IC50= 5 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | Microbial membrane disruption | NA | NA | NA | 1996 | 8641802 |
| antitb_1712 | Porcine leucocyte peptide (PG-1) | RGGRLCYCRRRFCVCVGR | Free | Free | Disulphide linkage 6-15 and 8-17 | Cyclic | 18 | L | Cationic | Natural | porcine neutrophil leucocyte | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37 Ra | MIC = 50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | Microbial membrane disruption | NA | NA | NA | 1996 | 8641802 |
| antitb_1716 | Human neutrophil peptide (HNP-1) | ACYCRIPACIAGERRYGTCIYQGRLWAFCC | Free | Free | Disulphide linkage between cys2-cys30, cys4-cys19,cys9-cys29 | Cyclic | 30 | L | Cationic | Natural | Human neutrophil | Mycobacterium avium- mycobacterium intracellularae | Mycobacterium avium- mycobacterium intracellularae strain 25291 | Reduction in CFU at 5 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1992 | 1398982 |
| antitb_1717 | Human neutrophil peptide (HNP-1) | ACYCRIPACIAGERRYGTCIYQGRLWAFCC | Free | Free | Disulphide linkage between cys2-cys30, cys4-cys19,cys9-cys29 | Cyclic | 30 | L | Cationic | Natural | Human neutrophil | Mycobacterium avium- mycobacterium intracellularae | Mycobacterium avium- mycobacterium intracellularae strain 25291 | Reduction in CFU at 50 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1992 | 1398982 |
| antitb_1718 | Human neutrophil peptide (HNP-2) | ACYCRIPACIAGERRYGTCIYQGRLWAFCC | Free | Free | Disulphide linkage between cys1-cys29, cys3-cys18,cys8-cys28 | 29 | L | Cationic | Natural | Human neutrophil | Mycobacterium avium- mycobacterium intracellularae | Mycobacterium avium- mycobacterium intracellularae strain 25291 | Reduction in bacterial load to 64 % at 5 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1992 | 1398982 | |
| antitb_1719 | Human neutrophil peptide (HNP-3) | DCYCRIPACIAGERRYGTCIYQGRLWAFCC | Free | Free | Disulphide linkage between cys2-cys30, cys4-cys19,cys9-cys29 | 30 | L | Cationic | Natural | Human neutrophil | Mycobacterium avium- mycobacterium intracellularae | Mycobacterium avium- mycobacterium intracellularae strain 25291 | Reduction in bacterial load to 61 % 5 μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1992 | 1398982 | |
| antitb_1720 | Human neutrophil peptide (HNP-1) | ACYCRIPACIAGERRYGTCIYQGRLWAFCC | Free | Free | Disulphide linkage between cys2-cys30, cys4-cys19,cys9-cys29 | Cyclic | 30 | L | Cationic | Natural | Human neutrophil | Mycobacterium avium- mycobacterium intracellularae | Mycobacterium avium- mycobacterium intracellularae strain SJB | Reduction in CFU/well 91.8 ± 1.1 at peptide concentration 50μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1992 | 1398982 |
| antitb_1721 | Human neutrophil peptide (HNP-1) | ACYCRIPACIAGERRYGTCIYQGRLWAFCC | Free | Free | Disulphide linkage between cys2-cys30, cys4-cys19,cys9-cys29 | Cyclic | 30 | L | Cationic | Natural | Human neutrophil | Mycobacterium avium- mycobacterium intracellularae | Mycobacterium avium- mycobacterium intracellularae strain 292524 | Reduction in CFU/well70.6 ± 0.6 at peptide concentration 50μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1992 | 1398982 |
| antitb_1722 | Human neutrophil peptide (HNP-1) | ACYCRIPACIAGERRYGTCIYQGRLWAFCC | Free | Free | Disulphide linkage between cys2-cys30, cys4-cys19,cys9-cys29 | Cyclic | 30 | L | Cationic | Natural | Human neutrophil | Mycobacterium avium- mycobacterium intracellularae | Mycobacterium avium- mycobacterium intracellularae strain 475049 | Reduction in CFU/well 32.5 ± 10.7 at peptide concentration 50μg/ml | in vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1992 | 1398982 |
| antitb_1776 | Sesquin | KTCENLADTY | Free | Free | None | Linear | 10 | L | Cationic | Natural | Isolated from ground beans (Vigna sesquipedalis cv. ‘Ground Bean’) | Mycobacterium phlei | Mycobacterium phlei | IC50 = 87 ± 5 µM | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial, Antifungal | 2005 | 15949629 |
| antitb_1777 | Mitogenic defensin | MEKKSFAGLCFLFLVLFVAQECVLQTEAKTCENLADTFRGPCFATGNCDDHCKNKEHLLRGRCRDDFRCWCTRNC | Free | Free | Disulfide linkage | Cyclic | 75 | L | Cationic | Natural | From the seeds of white cloud beans (Phaseolus vulgaris cv. ‘white cloud bean’) | Mycobacterium phlei | Mycobacterium phlei | IC50 = 86 ± 6 µM | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial, Antifungal | 2006 | 16687191 |
| antitb_1806 | NK-2 | KILRGVCKKIMRTFLRRISKDILTGKK | Free | Amidation | None | Linear | 27 | L | Cationic | Protein Derived | Core region of the lymphocytic effector protein NK-lysin | Mycobacterium smegmatis | Mycobacterium smegmatis mc2155 | After 24 h more than 70% killing of M. smegmatis was found at 30 μM | In vitro | mouse macrophage RAW 264.7 | 10 μM NK-2 diminished the intracellular bacterial loadwhen compared to the untreated macrophages | Non-toxic | NA | NA | NA | NA | NA | NA | NA | 2011 | 21396418 |
| antitb_1807 | NK-3 | KILRGVCKKIMRTFLRRISKDILTGKK | Free | Amidation | None | Linear | 27 | L | Cationic | Protein Derived | Core region of the lymphocytic effector protein NK-lysin | Mycobacterium bovis | Mycobacterium bovis BCG Pasteur (ATCC35734) | After 24 h, more than 78% killing was observed at 30 μM | In vitro | mouse macrophage RAW 264.8 | 11 μM NK-2 diminished the intracellular bacterial loadwhen compared to the untreated macrophages | Non-toxic | NA | NA | NA | NA | NA | NA | NA | 2011 | 21396418 |
| antitb_1808 | Ci-MAM-A24 | WRSLGRTLLRLSHALKPLARRSGW | Free | Amidation | None | Linear | 24 | L | Cationic | Protein Derived | Derived from immune cells of Ciona intestinalis, | Mycobacterium smegmatis | Mycobacterium smegmatis mc2155 | 45% bacterial population was killed at 10 μM peptide incubated for 1 hr | In vitro | mouse macrophage RAW 264.9 | NA | Slight toxic (two-fold decrease in cell viability was observed at 50 μM | NA | NA | NA | NA | NA | NA | NA | 2011 | 21396418 |
| antitb_1809 | Ci-MAM-A25 | WRSLGRTLLRLSHALKPLARRSGW | Free | Amidation | None | Linear | 24 | L | Cationic | Protein Derived | Derived from immune cells of Ciona intestinalis, | Mycobacterium bovis | Mycobacterium bovis BCG Pasteur (ATCC35734) | After 24 h, more than 78% killing was observed at 30 μM | In vitro | mouse macrophage RAW 264.10 | NA | Slight toxic (two-fold decrease in cell viability was observed at 50 μM | NA | NA | NA | NA | NA | NA | NA | 2011 | 21396418 |
| antitb_1810 | Mcdef | GFGCPNDYSCSNHCRDSIGCRGGYCKYQLICTCYGCKKRRSIQE | Free | Free | 4 disulfide linkages between 4-25, 10-31, 14-33, 20-36 | Cyclic | 44 | L | Cationic | Protein Derived | detected in hemocytes of Manila clams (Ruditapes philippinarum). | Mycobacterium fortuitum | Mycobacterium fortuitum | MIC >20 μM | In vitro | NA | NA | NA | NA | NA | NA | NA | NA | NA | Antibacterial (Staphylococcus aureus KCTC 1916, Streptococcus iniae KCTC 3651, orynebacterium diphtheriae, Bacillus subtilis, ibrio logei KCCM 12281, Vibrio salmonicida KCCM 41663) | 2011 | 21945146 |
| antitb_1811 | LL- 37 | LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES | Free | Free | None | Linear | 37 | L | Cationic | Natural | Human cells | Mycobacterium tuberculosis | Mycobacterium tuberculosis strain H37Rv | MIC = 5 μM | Both | NA | NA | NA | Male BALB/c mice | a significant reduction in bacilli loads | NA | Disruption of cell wall and membrane | cell wall and membrane | NA | Antibacterial (P.aeruginosa) | 2012 | 23141114 |
| antitb_1812 | mouse CRAMP | GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ | Free | Free | None | Linear | 34 | L | Cationic | Natural | Mouse cells | Mycobacterium tuberculosis | Mycobacterium tuberculosis strain H37Rv | MIC = 4 μM | Both | NA | NA | NA | Male BALB/c mice | a significant reduction in bacilli loads | NA | Disruption of cell wall and membrane | cell wall and membrane | NA | Antibacterial (P.aeruginosa) | 2012 | 23141114 |
| antitb_1813 | E2 (also known as Bac8c) | RIWVIWRR | Free | Amidation | None | Linear | 8 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis strain H37Rv | MIC = 2.6 ± 0.34 g/mL | Both | NA | NA | NA | Male BALB/c mice | a significant reduction in bacilli loads | NA | Disruption of cell wall and membrane | cell wall and membrane | NA | Antibacterial (P.aeruginosa) | 2012 | 23141114 |
| antitb_1814 | E6 (also called Sub3) | RRWRIVVIRVRR | Free | Amidation | None | Linear | 12 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis strain H37Rv | MIC = 3.2 ± 0.10 g/mL | Both | NA | NA | NA | Male BALB/c mice | a significant reduction in bacilli loads | NA | Disruption of cell wall and membrane | cell wall and membrane | NA | Antibacterial (P.aeruginosa) | 2012 | 23141114 |
| antitb_1815 | CP26 | KWKSFIKKLTSAAKKVVTTAKPLISS | Free | Free | None | Linear | 26 | L | Cationic | Protein Derived | derived from a hybrid peptide comprising the amphipathic α -helical Nterminal region of cecropin A and the hydrophobic N-terminal α-helix of the bee venom peptide melittin | Mycobacterium tuberculosis | Mycobacterium tuberculosis strain H37Rv | MIC = 2.1 ± 0.33 g/mL | Both | NA | NA | NA | Male BALB/c mice | a significant reduction in bacilli loads | NA | Disruption of cell wall and membrane | cell wall and membrane | NA | Antibacterial (P.aeruginosa) | 2012 | 23141114 |
| antitb_1816 | ubiquitin-derived peptide Ub2 | STLHLVLRLRGG | Free | Free | None | Linear | 12 | L | Cationic | Protein Derived | Ubiquitin derived | Mycobacterium smegmatis | Mycobacterium smegmatis mc2155 | MIC = 50 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1817 | Ub2scr | RLGRLVSLHTLG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub2 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2156 | MIC > 400 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1818 | Ub2S1A | ATLHLVLRLRGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub3 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2157 | MIC = 25 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1819 | Ub2T2A | SALHLVLRLRGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub4 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2158 | MIC = 50 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1820 | Ub2L3A | STAHLVLRLRGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub5 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2159 | MIC = 100 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1821 | Ub2H4A | STLALVLRLRGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub6 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2160 | MIC > 400 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1822 | Ub2L5A | STLHAVLRLRGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub7 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2161 | MIC = 50 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1823 | Ub2V6A | STLHLALRLRGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub8 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2162 | MIC = 25 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1824 | Ub2L7A | STLHLVARLRGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub9 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2163 | MIC = 100 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1825 | Ub2R8A | STLHLVLALRGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub10 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2164 | MIC > 400 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1826 | Ub2L9A | STLHLVLRARGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub11 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2165 | MIC = 50 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1827 | Ub2R10A | STLHLVLRLAGG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub12 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2166 | MIC > 400μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1828 | Ub2G11A | STLHLVLRLRAG | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub13 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2167 | MIC > 400 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1829 | Ub2G12A | STLHLVLRLRGA | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | Analogue of Ub14 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2168 | MIC > 400 μM | In vitro | None | NA | NA | NA | NA | NA | Micellar aggregate channel model | Cytoplasmic membrane | NA | NA | 2012 | 23173767 |
| antitb_1830 | Peptide Ub 17.1 | KTLTGKTITLE | Free | Free | None | Linear | 11 | L | Cationic | Synthetic | Analogue of Ub15 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2169 | MIC = 50 μM | In vitro | None | NA | NA | NA | NA | NA | Targeting the membrane in a less disruptive manner | Cell Membrane | NA | NA | 2012 | 23173767 |
| antitb_1831 | Peptide Ub 21 | EVEPSDTIENVKAKIQ | Free | Free | None | Linear | 16 | L | Cationic | Synthetic | Analogue of Ub16 | Mycobacterium smegmatis | Mycobacterium smegmatis mc2170 | MIC = 50 μM | In vitro | None | NA | NA | NA | NA | NA | Targeting the membrane in a less disruptive manner | Cell Membrane | NA | NA | 2012 | 23173767 |
| antitb_1860 | Anoplin | GLLKRIKTLL | Free | Amidation | None | Linear | 10 | L | Cationic | Natural | Derived from the venom sac of the solitary wasp, Anoplius samariensis | Mycobacterium smegmatis | Mycobacterium smegmatis mc2 155 | MIC = 200 μg/mL | In vitro | RBC | NA | Non toxic to erythrocytes | NA | NA | NA | NA | NA | NA | Antifungal (C. parapsilosis) and Antibacterial (Escherichia coli DH5a, Pseudomonas aeruginosa PAO, and Zymomonas mobilis ATCC 10988; Gram-positive bacteria: Bacillus subtilis DELTA) | 2016 | 27862650 |
| antitb_1869 | Mastoparan Polybia-MPII | INWLKLGKMVIDAL | Free | Free | None | Linear | 14 | L | Cationic | Natural | Isolated from venom of the social wasp Pseudopolybia vespiceps testacea | Mycobacterium abscessus | Mycobacterium abscessus subsp. massiliense GO06 | 80% inhibition at 12.5 μM | In vitro | murine macrophages, human and mouse erythrocytes | 80% inhibition at 12.5 μM | 50% hemolysis at 24.18 μM and 48.47 μM against mouse and human erythrocytes respectively | NA | NA | NA | membrane pore formation | cell membrane | NA | Antifungal (Candida albicans and Cryptococcus neoformans) and Antibacterial (Staphylococcus aureus) | 2017 | 28108242 |
| antitb_1870 | Tat(47–57) | YGRKKRRQRRR | Free | Free | None | Linear | 11 | L | Cationic | Protein Derived | HIV transactivator protein | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv (ATCC 27294) | MIC >300 μM | In vitro | RBC | NA | 50% hemolysis at >300 μM | NA | NA | NA | NA | NA | NA | Antibacterial (Streptococcus pneumoniae) | 2017 | 28314993 |
| antitb_1871 | Penetratin | RQIKIWFQNRRMKWKK | Free | Free | None | Linear | 16 | L | Cationic | Protein Derived | Drosophila Antennapedia protein | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv (ATCC 27294) | MIC >300 μM | In vitro | RBC | NA | 50% hemolysis at >300 μM | NA | NA | NA | NA | NA | NA | Antibacterial (Streptococcus pneumoniae) | 2017 | 28314993 |
| antitb_1872 | Transportan | AGYLLGKINLKALAALAKKIL | Free | Free | None | Linear | 21 | L | Cationic | Synthetic | Constructed from Galanin and Mastoparan proteins | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv (ATCC 27294) | MIC = 80 μM | In vitro | RBC | NA | 50% hemolysis at 38.0 ± 3.79 μM | NA | NA | NA | NA | NA | NA | Antibacterial (Streptococcus pneumoniae) | 2017 | 28314993 |
| antitb_1873 | Magainin | GIGKFLHSAKKFGKAFVGEIMNS | Free | Free | None | Linear | 23 | L | Cationic | Natural | Peptide from Xenopus laevis skin | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv (ATCC 27294) | MIC >300 μM | In vitro | RBC | NA | 50% hemolysis at >300 μM | NA | NA | NA | NA | NA | NA | Antibacterial (Streptococcus pneumoniae) | 2017 | 28314993 |
| antitb_1874 | Buforin II (5–21) | RAGLQFPVGRVHRLLRK | Free | Free | None | Linear | 17 | L | Cationic | Natural | Peptide from the stomach tissue of Bufo bufo garagrizans | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv (ATCC 27294) | MIC >300 μM | In vitro | RBC | NA | 50% hemolysis at >300 μM | NA | NA | NA | NA | NA | NA | Antibacterial (Streptococcus pneumoniae) | 2017 | 28314993 |
| antitb_1875 | GranF2 | VCRTGRSRWRDVCRNFMRRYQSR | Free | Free | None | Linear | 23 | L | Cationic | Protein Derived | Peptide derived from Granulysin protein | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv (ATCC 27294) | MIC >300 μM | In vitro | RBC | NA | 50% hemolysis at >300 μM | NA | NA | NA | NA | NA | NA | Antibacterial (Streptococcus pneumoniae) | 2017 | 28314993 |